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35 Cards in this Set
- Front
- Back
bicarbonate is secreted by __ cells?
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epithelial cells
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what stimulates release of bicarbonate?
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acetylcholine
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what make the mucus layer alkaline?
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bicarbonate
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what is the thickness of the mucus and bicarbonate layer?
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0.2 MM thick
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__ is a glycoprotein that is secreted by the parietal cells of the stomach
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intrinsic factor
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what is required for absorption and binding of B12
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intrinsic factors
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the exocrine pancrease:
the pancreas is also an endocrine organ secreting hormones it plays a role in __ and ___ metabolism |
lipid and carbohydrate
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what kind of hormones does the endocrine pancreas secrete?
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insulin and glucagon
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what does the endocrine pancreas maintain?
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normal blood glucose concentration
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cells in the exocrine and endocrine pancreas are arranged in grape-like clusters called ___
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acini
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what do acini secrete?
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the enzyme component of pancreatic juice
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____ are endocrine cells that secrete insulin, glucagon, somatostatin and pancreatic polypeptide
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islets of langerhans
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the substances produced by the acini (the enzyme component of pancreatic juice) are drain into the ___
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duodenum
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what kind of cells line the ducts and produce the fluid component of the pancreatic fluid?
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columnar epithelial cells
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what do the endocrine cells, the islet of langerhans secrete?
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insulin, glucagon, somatostatin, and pancreatic polypeptide
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how much pancreatic juice is secreted per day?
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1 kg
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pancreatic exocrine juice is composed of what two types of components
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aqueous components (secreted by columnar epithelial cells that line the ducts) and enzyme component(helps to digest carbs, proteins, and fats secreted by acinar cells)
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what are the three neural and hormonal signals that control pancreatic secretion?
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cholinergic stimulation, secretin, CCK-cholecystokinin
these signals are triggered by the presence of acid and digestion products in the duodenum |
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enzyme components of pancreatic juice:
secretions of __ cells and cells of the ___ make up the enzyme component of the exocrine juice composed |
acinar cells and cells of the intercalated ducts make up the enzyme components
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what component of the exocrine juice excreted by the pancrease is secreted by columnar epithelial cells that line the ducts?
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aqueous component
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proteases in pancreatic juice:
Proteases are secreted in zymogen form in the pancreas: what are the three? |
trypsinogen, chrmotrypsinogen, procarboxypeptidase
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what component of the exocrine juice excreted by the pancrease is secreted by acinar cells and is used to help digest carbohydrates, proteins, and fats?
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enzyme components
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proteases in pancreatic juice:
Proteases are secreted in zymogen form in the pancreas: what converts trypsinogen to trypsin? |
enterokinase in the intestine
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proteases in pancreatic juice:
Proteases are secreted in zymogen form in the pancreas: what converts chymotrypsinogen to chymotrypsin? |
trypsin in the intestine
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proteases in pancreatic juice:
Proteases are secreted in zymogen form in the pancreas: what converts procarboxypeptidase to carboxypeptidase? |
trypsin in the intestine
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what are the three proteases in pancreatic juice that is secreted in zymogen form?
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trypsinogen, chymotrypsinogen, procarboxypeptidase
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the major proteases in the intestine are ___,__, and ___
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trypsin, chymotrypsin, carboxypeptidase
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what major proteases are secreted by the intestine catalyzes the breakdown of dietary proteins to peptones, peptides and amino acids
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trypsin, chymotrypsin
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what major proteases are secreted by the intestine that cleaves peptides from the N and C terminal
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carboxypeptidase
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the major lipases that are in pancreatic juices are __,__,___
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triacylglycerol hydrolase, cholesterol ester hydrolase, phospholipase A2
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what is produced primarily by the columnar epithelial cells that line the pancreatic ducts and is enriched with bicarbonate
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aqueous component of pancreatic juice
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as rate of secretion of pancreatic juice increases, what happens to HCO3 and Cl, and K, and Na
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HCO3 increases,
Cl decreases Na remains high through out secreation rates and K remains low through out secreation rates |
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___ is where food is chewed and not swallowed
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sham feeding
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__nerve impulses stimulate pancreatic secretion
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vagal
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___ induces secretion of a low volume of pancreatic juice with a high protein content
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sham feeding
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