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35 Cards in this Set

  • Front
  • Back
bicarbonate is secreted by __ cells?
epithelial cells
what stimulates release of bicarbonate?
acetylcholine
what make the mucus layer alkaline?
bicarbonate
what is the thickness of the mucus and bicarbonate layer?
0.2 MM thick
__ is a glycoprotein that is secreted by the parietal cells of the stomach
intrinsic factor
what is required for absorption and binding of B12
intrinsic factors
the exocrine pancrease:

the pancreas is also an endocrine organ secreting hormones

it plays a role in __ and ___ metabolism
lipid and carbohydrate
what kind of hormones does the endocrine pancreas secrete?
insulin and glucagon
what does the endocrine pancreas maintain?
normal blood glucose concentration
cells in the exocrine and endocrine pancreas are arranged in grape-like clusters called ___
acini
what do acini secrete?
the enzyme component of pancreatic juice
____ are endocrine cells that secrete insulin, glucagon, somatostatin and pancreatic polypeptide
islets of langerhans
the substances produced by the acini (the enzyme component of pancreatic juice) are drain into the ___
duodenum
what kind of cells line the ducts and produce the fluid component of the pancreatic fluid?
columnar epithelial cells
what do the endocrine cells, the islet of langerhans secrete?
insulin, glucagon, somatostatin, and pancreatic polypeptide
how much pancreatic juice is secreted per day?
1 kg
pancreatic exocrine juice is composed of what two types of components
aqueous components (secreted by columnar epithelial cells that line the ducts) and enzyme component(helps to digest carbs, proteins, and fats secreted by acinar cells)
what are the three neural and hormonal signals that control pancreatic secretion?
cholinergic stimulation, secretin, CCK-cholecystokinin

these signals are triggered by the presence of acid and digestion products in the duodenum
enzyme components of pancreatic juice:

secretions of __ cells and cells of the ___ make up the enzyme component of the exocrine juice composed
acinar cells and cells of the intercalated ducts make up the enzyme components
what component of the exocrine juice excreted by the pancrease is secreted by columnar epithelial cells that line the ducts?
aqueous component
proteases in pancreatic juice:

Proteases are secreted in zymogen form in the pancreas:

what are the three?
trypsinogen, chrmotrypsinogen, procarboxypeptidase
what component of the exocrine juice excreted by the pancrease is secreted by acinar cells and is used to help digest carbohydrates, proteins, and fats?
enzyme components
proteases in pancreatic juice:

Proteases are secreted in zymogen form in the pancreas:

what converts trypsinogen to trypsin?
enterokinase in the intestine
proteases in pancreatic juice:

Proteases are secreted in zymogen form in the pancreas:

what converts chymotrypsinogen to chymotrypsin?
trypsin in the intestine
proteases in pancreatic juice:

Proteases are secreted in zymogen form in the pancreas:

what converts procarboxypeptidase to carboxypeptidase?
trypsin in the intestine
what are the three proteases in pancreatic juice that is secreted in zymogen form?
trypsinogen, chymotrypsinogen, procarboxypeptidase
the major proteases in the intestine are ___,__, and ___
trypsin, chymotrypsin, carboxypeptidase
what major proteases are secreted by the intestine catalyzes the breakdown of dietary proteins to peptones, peptides and amino acids
trypsin, chymotrypsin
what major proteases are secreted by the intestine that cleaves peptides from the N and C terminal
carboxypeptidase
the major lipases that are in pancreatic juices are __,__,___
triacylglycerol hydrolase, cholesterol ester hydrolase, phospholipase A2
what is produced primarily by the columnar epithelial cells that line the pancreatic ducts and is enriched with bicarbonate
aqueous component of pancreatic juice
as rate of secretion of pancreatic juice increases, what happens to HCO3 and Cl, and K, and Na
HCO3 increases,
Cl decreases
Na remains high through out secreation rates and K remains low through out secreation rates
___ is where food is chewed and not swallowed
sham feeding
__nerve impulses stimulate pancreatic secretion
vagal
___ induces secretion of a low volume of pancreatic juice with a high protein content
sham feeding