• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/10

Click to flip

10 Cards in this Set

  • Front
  • Back
Enteroviruses (coxsackie/echovirus)

Viral
Picorniviridae family
Icosahedral +ssRNA

most common cause of viral meningitis
‐fever, headache, stiff neck, petechial rash (hand & mouth) good recovery
‐newborns more susceptible
Arbovirus
(West Nile)

Viral
Flaviviridae family
Icosahedral, enveloped, +ssRNA

arthropod vector
HSV1, HSV2,
CMV, EBV,
VZV

Viral
Herpesviridae family
Icosadeltahedral, enveloped, dsDNA

‐can cause lytic, persistent, and latent infections
‐has 10 different glycoproteins on envelope for
attachment
‐sensitive to acid, solvents, drying
Mumps

Viral
Paramyxoviridae family
Helical, Enveloped, Segmented
‐ssRNA

parotid swelling
Streptococcus
pneumonia

(most Bacterial common
cause)
gram+ Diplococci

catalase (‐), alpha hemolysis in aerobic (characteristic green color on green agar), beta hemolytic in anaerobic
‐Cell wall contains C‐polysaccharide, F‐antigen, phosphocholine (important in adhesion to epithelial cells)
‐Pneumolysin (creates pores in cells), IgA protease (kills IgA)
‐can also cause pneumonia, sinusitis
‐vaccine is polysaccharide conjugate. For young children because young children have weak T‐independent reponses
Neisseria
meningitides

2nd most common Bacterial cause
gram‐ diploocci

catalase+, oxidase+, ferments glucose and maltose (whereas N. gonorrhea can only
ferment glucose)
‐porins porA and porB, pili and flagella
‐outer membrane contains lipooligosaccharide (lipid A, core oligosaccharide, but no O antigen) instead of LPS
‐can cause pneumonia (cough, chest pain, fever, chills)
‐deadly if untreated
Streptococcus
agalactiae
(group B strep)
gram+ Cocci
chains

catalase‐, beta hemolytic, Group B Lancefield antigen
‐common in neonates (50%). Second most common neonate meningitis bacteria is E.
coli (25%)
Haemophilus
influenzae

Bacterial
gram‐ Rod

generally aerobic, catalase+, oxidase+
‐colonizes URT, conjunctiva, genital tract
‐grows as tiny colonies next to S. aureus (satellite phenomenon) because S. aureus
produces Factor V and Factor X required for its growth
Listeria
monocytogenes
(common in
cold areas ie
Canada)

Bacterial
gram+ Short Rods (coccobacilli)

catalase+, beta hemolytic, cAMP test+, motile
‐intracellular
‐transmitted through food (unpasteurized milk)
‐mechanism of entry into cells: endocytosed by gut epithelium, avoids killing by Listeriolysin A and Phospholipase C, replicates inside cell, uses actin assembly (ActA) to extend membrane to neighbor cell, PrfA regulates cell lysis and replication and bacterium gets endocytosed again
‐can go from gut epithelium to macrophages (avoiding immune system) which can then cross to meningeal cells
Staphylococcus
epidermidis

bacterial
gram+ Cocci
clusters

catalase+, coagulase‐, gamma hemolytic