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5 Cards in this Set
- Front
- Back
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Acute Lymphoblastic Leukemia/Lymphoma
(Precursor B and T cell Neoplasm) |
Mostly of B cell origin
PAS positive TdT - a specialized DNA polymerase used for detection as it is only on pre-B abd T lymphoblasts Pre-B have CD19 Pre-T have CD1A Philadelphia Chromosome t(9,22) common cause |
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Acute Lymphoblastic Leukemia/Lymphoma Symptoms
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Abrupt onset
Fatigue due to anemia Bleeding due to dec. plateletes Bone Pain and tenderness due to marrow expansion |
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Chronic Lyphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)
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Dividing cells aggregate in proliferation centers
Smudge Cells are seen in CLL which are small lymphocytes that are disrupted CD19 and CD20 Late onset 50 years and more common in men |
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Follicular Lymphoma
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Most common of NHL
t(14;18) and is due to BCL@ increase |
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Diffuse Large B-Cell Lymphoma
(DLBCL) |
Show a relatively large
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