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30 Cards in this Set

  • Front
  • Back
What are the pressures measured relative to?
Atmospheric pressure
What is the ideal gas law and what does it apply to?
Dry gas
PV=nRT
Pa
m(^3)
J.K(^-1).mol(^-1)
K
At a constant temperature and volume, pressure is proportional to
number of moles
What is a partial pressure?
What does it depend on?
The pressure exerted by each individual gas

number of moles in the given volume + temp
Which gradients do convection and diffusion travel down?
bulk + partial pressure gradient
What is Dalton's law?
Each gas in adry mixture exerts a partial pressure proportional to its fractional share of the share of the total volume

Pgas = Fgas x total pressure
What is the effect of altitude on barometric pressure?
halves every 5450m
What is the effect of altitude on Pgas?
lowers it
What are STPD and BTPS?
standard temp (O celcius) pressue (101kPa) dry
body temp (37 celcius) pressure (101kPa) saturated
To calculate the dry mixture, what must be done to the pressure of the saturated gas?
PH2O must be subtracted from the total volume

so at BPS = Pgas = Fgas x (barometric pressure - PH2O)
What is the value of intrapleural fluid?
only a few ml
What state is the pleura in?
Virtual contact - virtually no space between the space
How many pleural sacs are there?
2, one for R and one for L lung
Where can we measure pressures?
outside the chest wall (Patm/PB)
between the pleural membrans (Ppl)
inside the alveoli (PA)
inside the airways (Paw)
When there is no airway, what is the value of PA?
0
What is the value of intrapleural pressure when there is no airway?
negative
How do you work out transmural/distending pressures?
Pin - Pout
What does a positive distending pressure mean?
It's filling/getting larger
At FRC, the lungs are
partially inflated
Why are the lungs partially inflated at FRC?
equilibrium between alveoli (want to collapse/is partially inflated) and chest wall (wants to expand/is partially compressed)

lung distending pressure: PA - Ppl = o - -1 = +1
chest wall distending pressure : Ppl - PB = -1- 0 = -1
What happens in a pneumothorax?
pressures equilibrate
chest wall expands
Ppl = PB = 0

lung collapses
PA = Ppl = 0
What is responsible for inspiration?
Respiratory muscles
What is responsible for passive expiration?
elastic recoil
What is Boyle's law?
At constant temperature and number of moles, pressure is inversely proportional to volume
Where is the diaphragm located?
C3-C5
What does the diaphragm do?
Lengthens (front to back and side to side) the thoracic cavity by contracting
Where are the external intercostal muscles?
T1-T11
What do the external intercostals do?
Expand the ribcage: +
What is the sequence of events for quiet inspiration?
thorax expands
Ppl falls
Lung distending pressure increases
Lungs expand
PA falls below PB
Air flows into lungs

exact opposite for expiration
What 2 factors must be overcome to allow inspiration to happen?
stretching of the elastic components of the respiratory system (15%)
overcoming the resistance to airflow (85%)