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39 Cards in this Set

  • Front
  • Back

Aerobic non spore forming gram +ve bacilli

Corynebacterium


Gram +ve bacilli characterized by cub shape

Corynebacterium

Why bacilli of diphtheria appear beaded when stained with methylene blue stain

Due to presence of metachromatic granules

Culture of c. Dephtheria

Enriched media eg. Blood agar and loffelers serum



Slective differential media (blood tellutite agar)

Corynebacterium colony on selective deferential media appears

Gray/black

Why not all dephtheria is toxigenic?

1- as not all dephtheria are lysogenic


2- as it is characteristic of prophage not bacterial dna

Transmitted by case or carrier 🧠 T

Staph. Aureus


Staph. Epidermidis


Strept. Agalactia


Strept. Pneumonae


C.dephtheria

Componentes of local pseudomembrane

Cell debris


Infection products


Fibrinous exudates

Complication of dephtheria (اسباب الوفاه)

1-extension of pseudomembrane into larenx ▶️ airway obstraction


2-myocarditis ▶️heart failure


3-nerve paralysis (especially cranial n)


Must be done immediately to dephtherial patient

Resp support


Antitoxins

Differential morphological characteristic of lesteria from other corynebacterium

Being motile

Can grow in cold temperature 4C

Lesteria

The only listeria species that infect human

Listeria monocytogenes

Listeria escape phogcytosis by


.....


And escape immune defensive mechanism by....

Lesteriolysin O



Actin rockets

Mode of transmission of listeria

1- feces of animal


2-contaminated vegetables and milk


3-vertical transmission

Listeria has longer incubation periode than staph aureus

As it invade the intestinal epithelium by itself not by its toxins

What type of food favorable by listeria

Dairy products


Under cooked meat

Can be gram +ve or - ve

Gardnerella vaginalis

Associated with bacterial vaginosis

Gardernella vaginalis

Laboratory diagnosis of gardnerella vaginalis

Clue cells with almost abcense of lactobacilli

Anaerobic non spore forming gram +ve bacilli

Propionibacterium


Lactobacilli

Has a typecal morphology of diphtheroids

Propionibacterium

Has probiotic effect

Lactobacilli

Characteristic of genus of mycobacterium

1-acid fasness


2- slow rate of growth


3-obligate aerobe

AFB florecence compared to zein neelsen method

More sensitive


Faster


Less specific

Steps of Sputum processing in TB contaminated sputum

1-liquifaction of Sputum


2-centrifugation of mycobacterium


3-decontamination of normal flora

What type of broth used in fluid media system in AFB culture

Middlebrook broth

QuantaFERON test compared to Tuberculin test

More spesific as it wont give false +ve resultes

Ist line drugs agains TB

Isoniazid


Rifambin


Pyrenzemide


Ethambutol.


Streptomycin

Ttt of latent tb infection

6 to 9 month izoniazid


To patient who are recently turned +ve


And to +ve patient who susbected to be imunocompramized

Why skin and superfacial nerves is the most affected by M. Leprae

Is it grow best in low temp (30C)

How to replase heat in kinyoun method

By phenol

1st line drugs against tb

Refambin


Isoniazid


Pyrazinamide


Ethambutol


Ttt of latent tb infection

Izoniazid for 6 to 9 months to


Resent +ve


Or patient subjected to be imunocompramized

Resistance of NTM

Much more than TB

Ttt of LL

Refampicin clofazimine dapsone


For 2 years

TL ttt

Refampicin for 6 months

Most common site of reactivation of TB

Apex of the lung

Route of administration of BCG

Intradermally