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84 Cards in this Set
- Front
- Back
Define Infection
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Type of disease that is caused by a microbe
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Define Transient
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Normal flora that is here today but gone tomorrow
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Define Symbiosis
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A relationship between 2 organisms living together
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Define Commensalism
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One organism is benefited and the other is unaffected.
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Define Mutualism
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Both organisms benefit from relationship
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Define Parasitism
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Damaging relationsip for Host only
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Define Opportunistic Flora
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Flora that's part of normal flora that if it overpopulates or moves can becomean opportunistic pathogen
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Define Communicable
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Transmitted from one person to another
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Define Contagious Infection
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Communicable; Very easily and rapidly transmitted
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Define Non-communicable
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Not spread from one to another; typically caused by normal flora or soil organisms
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What type of communicability do gas gane green, histoplasmosis, and tetanus have?
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Non-communicable
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Define Sporadic Infections
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Infections that happen just once in a while
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Define Endemic
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Disease is constantly present in a given population
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Define Epidemic
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Many people in a given area acquire a specific pathogen in a short preiod of time.
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Define Pandemic
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World-wide epidemic; Infection whose numbers are increasing
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Define Pandemic AFTER H1N1
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Every country reported a case of the infection
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Define Acute Infection
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an infection that develops rapidly but lasts for only 7-10 days
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Define Chronic Infection
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an infection that develops more slowly and lasts longer than an acute infection.
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Define Sub-acute
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Latent infections
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Define Local Infection
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Restricted to a relatively small area on the body
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Define Systemic infection
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Involves 2 or more systems
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Define Focal Infection
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Starts as local infection then spreads.
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Define Bacteremia
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Bacteria in blood
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Define Sepsis
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Bacteria multiplying in blood
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Define Viremia
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Virus in blood
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Define primary infection
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Perfectly healthy then acquire infection
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Define Secondary Infection
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Typically by opportunistic organism. It is a result of a primary infection
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Define Subclinical Infection
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You don't feel good but you have no specific symptoms
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What are 2 common subclinical infections?
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1-Polio
2-Hep. A |
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Define Incubation Period
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Period of time from when you first caught microbe to when you acquire symptoms
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Define Prodromal Period
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End of incubation period. You have no specific symptoms but you feel sick.
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Define Period of Illness
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Specific symptoms; white blood cell count is at its highest
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Define Period of Decline
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Symptoms lessen
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Define Convalescence
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Return to original state of health
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What are the 5 stages of the Development of an Infection?
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1) Incubation period
2) Prodromal Period 3) Period of Illness 4) Period of Decline 5) Convalescence |
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Define Resevoir
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Place in nature where microbes live
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Define Human Resevoir
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If you have infection you are natural resevoir for that microbe
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Define Carrier
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Individual who harbors pathogen but no symptoms
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Define Healthy Carriers (asymptomatic carriers)
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Individual who has pathogen but has no symptoms
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Define Incubation Carrier
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Individual who is in incubation stage of the infection
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Define Convalescent Carrier
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Had infection, is recovering, but can still transmit it to other individuals
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Define Chronic Carrier
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Individual who harbors pathogen for a long time after recovery
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Define Passive Carrier
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Medical and dental personel pick up pathogen while handeling contaminated materials and transmit it to other people
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Define Zoonosis
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Infection indigenous to animals but transmissible to humans
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Define Direct Contact transmission
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Transmitted person to person
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Define Indirect Contact
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Inanimate object between 2 hosts
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Define Fomite
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Contaminated object involved in the spread of infection
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Define Droplet Transmission
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Droplets out of nose or mought while coughing, laughing, sneezing, etc.
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Give examples of diseases usually spread through droplet transmission
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1-Pertussis
2-RSV 3-Pneumonia |
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Define Vehicle Transmission
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Something transports pathogen from one individual to another
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Define Airborne Transmission
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Pathogen is in small droplet and remains airborne for long distances
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Give examples of airborn transmissible pathogens
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fungi spores, staph, strep
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Define Vector Transmission
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Organism that transmits pathogen from one host to another
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What vector is used in transmitting Salmonella usually?
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Turtles
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What are 2 categories of vectors?
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1- Biological Vector
2- Mechanical Vector |
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Define biological vector
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A vector that is necessary for the vector's lifecycle
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Name and example of a biological vector
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Plasmodium
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Define Mechanical Vector
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Vector that is not necessary for vector's lifecycle
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Define Parenteral entry
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Direct deposit in skin
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What are the diseases that can cross the placenta?
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1-Syphilis
2-Toxoplasmosis 3-Other diseases (HBV, HIV, Chlamydia) 4-Rubella 5-CMV 6-Herpes simplex |
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Define Siz of inoculum
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The number of cells acquired
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Define Infectious Dose
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The number of cells that you must acquire in order for a disease to occur
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Name 3 structures that allow microbes to attach to host cells
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1-Pilus
2-Flagella 3-Capsules |
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Name to structures that protect against phagocytosis
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1-Biofilms
2-Capsules |
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Define Hemolysin
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an exoenzyme that destroys RBCs
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Define Leukocidins
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Exoenzymes that destroy WBCs
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Define Keratinase
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Exoenzyme that destroys protective skin layer
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Define Kinase
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Exoenzyme that dissolves blood clots
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Give to examples of organisms with keratinase
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1-Staph
2-Strep |
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Define coagulase
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Exoenzyme that creates blood clots
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WHat does IgA protease do?
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Degrades IgA to stop first entry defense
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WHat is the cell wall component in Strep pyogenes?
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M protein
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What is the cell wall component in Staph aureus?
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A Protein
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What are the 2 pathogens that have learned to survive inside paghocytic cells?
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Legionella and mycobacterium
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What is the difference between an exotoxin and endotoxin?
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An exotoxin is made by the microbe and then spat out while an endotoxin is a physical part of the cell
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Define exotoxin
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Chemical produced by some bacteria to help in metabolism
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What are the 3 groups of exotoxins?
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1-AB-toxin
2-Membrane disrupting 3-Superantigen |
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What are the two parts to the AB toxin?
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1-allows it to bind to host cell
2-allows damage to cell |
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Name 2 enzymes that fall under the category of membrane disrupting
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1-Hemolysin
2-Leukocidins |
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Define Super Antigen
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Bacterial proteins capable of triggering an incredibly strong inflammation response in the body
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What does a Diptheria exotoxin do?
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Damages heart and liver
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What does an Erythrogenic toxin do?
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It damages capillaries in skin
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Give an example of a disease caused by an erythrogenic toxin
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Scarlet Fever
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Define Vasomotor Shock
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Blood vessals dilate
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