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84 Cards in this Set

  • Front
  • Back
Define Infection
Type of disease that is caused by a microbe
Define Transient
Normal flora that is here today but gone tomorrow
Define Symbiosis
A relationship between 2 organisms living together
Define Commensalism
One organism is benefited and the other is unaffected.
Define Mutualism
Both organisms benefit from relationship
Define Parasitism
Damaging relationsip for Host only
Define Opportunistic Flora
Flora that's part of normal flora that if it overpopulates or moves can becomean opportunistic pathogen
Define Communicable
Transmitted from one person to another
Define Contagious Infection
Communicable; Very easily and rapidly transmitted
Define Non-communicable
Not spread from one to another; typically caused by normal flora or soil organisms
What type of communicability do gas gane green, histoplasmosis, and tetanus have?
Non-communicable
Define Sporadic Infections
Infections that happen just once in a while
Define Endemic
Disease is constantly present in a given population
Define Epidemic
Many people in a given area acquire a specific pathogen in a short preiod of time.
Define Pandemic
World-wide epidemic; Infection whose numbers are increasing
Define Pandemic AFTER H1N1
Every country reported a case of the infection
Define Acute Infection
an infection that develops rapidly but lasts for only 7-10 days
Define Chronic Infection
an infection that develops more slowly and lasts longer than an acute infection.
Define Sub-acute
Latent infections
Define Local Infection
Restricted to a relatively small area on the body
Define Systemic infection
Involves 2 or more systems
Define Focal Infection
Starts as local infection then spreads.
Define Bacteremia
Bacteria in blood
Define Sepsis
Bacteria multiplying in blood
Define Viremia
Virus in blood
Define primary infection
Perfectly healthy then acquire infection
Define Secondary Infection
Typically by opportunistic organism. It is a result of a primary infection
Define Subclinical Infection
You don't feel good but you have no specific symptoms
What are 2 common subclinical infections?
1-Polio
2-Hep. A
Define Incubation Period
Period of time from when you first caught microbe to when you acquire symptoms
Define Prodromal Period
End of incubation period. You have no specific symptoms but you feel sick.
Define Period of Illness
Specific symptoms; white blood cell count is at its highest
Define Period of Decline
Symptoms lessen
Define Convalescence
Return to original state of health
What are the 5 stages of the Development of an Infection?
1) Incubation period
2) Prodromal Period
3) Period of Illness
4) Period of Decline
5) Convalescence
Define Resevoir
Place in nature where microbes live
Define Human Resevoir
If you have infection you are natural resevoir for that microbe
Define Carrier
Individual who harbors pathogen but no symptoms
Define Healthy Carriers (asymptomatic carriers)
Individual who has pathogen but has no symptoms
Define Incubation Carrier
Individual who is in incubation stage of the infection
Define Convalescent Carrier
Had infection, is recovering, but can still transmit it to other individuals
Define Chronic Carrier
Individual who harbors pathogen for a long time after recovery
Define Passive Carrier
Medical and dental personel pick up pathogen while handeling contaminated materials and transmit it to other people
Define Zoonosis
Infection indigenous to animals but transmissible to humans
Define Direct Contact transmission
Transmitted person to person
Define Indirect Contact
Inanimate object between 2 hosts
Define Fomite
Contaminated object involved in the spread of infection
Define Droplet Transmission
Droplets out of nose or mought while coughing, laughing, sneezing, etc.
Give examples of diseases usually spread through droplet transmission
1-Pertussis
2-RSV
3-Pneumonia
Define Vehicle Transmission
Something transports pathogen from one individual to another
Define Airborne Transmission
Pathogen is in small droplet and remains airborne for long distances
Give examples of airborn transmissible pathogens
fungi spores, staph, strep
Define Vector Transmission
Organism that transmits pathogen from one host to another
What vector is used in transmitting Salmonella usually?
Turtles
What are 2 categories of vectors?
1- Biological Vector
2- Mechanical Vector
Define biological vector
A vector that is necessary for the vector's lifecycle
Name and example of a biological vector
Plasmodium
Define Mechanical Vector
Vector that is not necessary for vector's lifecycle
Define Parenteral entry
Direct deposit in skin
What are the diseases that can cross the placenta?
1-Syphilis
2-Toxoplasmosis
3-Other diseases (HBV, HIV, Chlamydia)
4-Rubella
5-CMV
6-Herpes simplex
Define Siz of inoculum
The number of cells acquired
Define Infectious Dose
The number of cells that you must acquire in order for a disease to occur
Name 3 structures that allow microbes to attach to host cells
1-Pilus
2-Flagella
3-Capsules
Name to structures that protect against phagocytosis
1-Biofilms
2-Capsules
Define Hemolysin
an exoenzyme that destroys RBCs
Define Leukocidins
Exoenzymes that destroy WBCs
Define Keratinase
Exoenzyme that destroys protective skin layer
Define Kinase
Exoenzyme that dissolves blood clots
Give to examples of organisms with keratinase
1-Staph
2-Strep
Define coagulase
Exoenzyme that creates blood clots
WHat does IgA protease do?
Degrades IgA to stop first entry defense
WHat is the cell wall component in Strep pyogenes?
M protein
What is the cell wall component in Staph aureus?
A Protein
What are the 2 pathogens that have learned to survive inside paghocytic cells?
Legionella and mycobacterium
What is the difference between an exotoxin and endotoxin?
An exotoxin is made by the microbe and then spat out while an endotoxin is a physical part of the cell
Define exotoxin
Chemical produced by some bacteria to help in metabolism
What are the 3 groups of exotoxins?
1-AB-toxin
2-Membrane disrupting
3-Superantigen
What are the two parts to the AB toxin?
1-allows it to bind to host cell
2-allows damage to cell
Name 2 enzymes that fall under the category of membrane disrupting
1-Hemolysin
2-Leukocidins
Define Super Antigen
Bacterial proteins capable of triggering an incredibly strong inflammation response in the body
What does a Diptheria exotoxin do?
Damages heart and liver
What does an Erythrogenic toxin do?
It damages capillaries in skin
Give an example of a disease caused by an erythrogenic toxin
Scarlet Fever
Define Vasomotor Shock
Blood vessals dilate