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16 Cards in this Set
- Front
- Back
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2 primary causes of Hyperthyroidism
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Hyperplasia/adenoma (ectopic thyroid)
malignant carcinoma |
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Risk Factors for Feline Hyperthyroidism
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BPA
Carpet exposure Single cats Cats that use litter PBDEs |
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Two breeds at a decreased risk for Feline Hyperthyroidism
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Siamese
Himalayans |
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Clinical signs of Feline hyperthyroidism in order of prevalence
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Weight loss (.92)
Polyphagia (.61) Hypertension (.53) Tachycardia (.48) PU/PD (.47) Systolic Murmur (.40) Diarrhea (.39) vomiting (.38) Dyspnea (.23) Arrhythmia (.12) Inappetance and lethargy (.09) Behavioral (.08) |
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Common bloodwork changes in feline hyperthyroidism
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Increased ALT (.85)
Increased ALP (.62) Polycythemia (.39) Increased BUN/Creatinine (.26) Macrocytosis (.20) Increased Phosphate (normal Ca+) (.18) UTI (.12) Increased BG (.05) Stress Leukogram Decreased USG |
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Things you would expect to see on Thoracic radiographs of a Feline Hyperthyroid patient
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Cardiomegaly
Pulmonary edema/effusion due to congestive heart failure Lung Nodules due to metastatic disease |
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Best tests for determining whether or not a cat is Hyperthyroid:
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1. tT4
2. fT4 3. T3 suppression test 4. TRH stim test 5. Thyroid scintigraphy ($) |
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What in the name of god could cause fT4 to increase while the tT4 decreased?
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Non-thyroidal illness.
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Treatments for Feline Hyperthyroidism
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Methimazole
I-131 Thyroidectomy Ablative injection |
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Adverse effects of Methimazole
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Bone marrow dyscrasias
GI issues Facial/neck pruritis Hepatotoxicity |
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Methimazole post-treatment
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Follow-up at 2 & 4 weeks
Check: - skin for pruritis - GI signs - CBC for dyscrasias - Chem panel for hepatotoxicity and renal disease - T4 for regulation |
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Second Drug of choice for Feline hyperthyroidism
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Iopanoic Acid/Ipodate
Shuts down T4 productiion conversion May develop tolerance |
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Best option for a unilateral hyperthyroid
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Thyroidectomy
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Disadvantages of thyroidectomy
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Increased rate of recurrence
Misses metastatic & ectopic disease Hypoparathyroidism (if bilateral) |
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Risks of Percutaneous Therapy
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Laryngeal Paralysis
Horner's Syndrome Dysphonia |
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Adjunctive therapy for HerT
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Beta Blockers to stabilize for thyroidectomy (atenolol, Propanolol)
Antihypertensives (Ca Channel Blockers, ACE inhibitors) |
