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7 Cards in this Set
- Front
- Back
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How is Mo transported in plasma?
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Bound to macroglobulin
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Excretion of Mo?
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Urine
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Homestatise?
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Urine: by excretion
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Name two Mo-dependent enzymes
& what are their rxns? |
Xanthine Oxidase:
hypoxanthine-->xanthine-->uric acid ** for purine synthesis Sulfite Oxidase: Sulfite-->sulfate Sulfite is toxic; sulfate needed in some rxns. |
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What genetic impairment can lead to a deficiency in Mo?
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The inability to synthesize the cofactor which Mo is in. This is the form that is used in enzymes.
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So what happens?
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Well, there is no measured activity of the ezymes; as a result, high levels of hypoxnathine, xanthine, and sulfite and in urine.
Condition is deadly. Shrinkage of brain, dislocation of eye lens, neurological issues. |
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What is the Mo-cofactor?
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It's the form of Mo which is used in enzymes. If you cannot produce the cofactor, you cannot use any of the enzymes. Not good!!
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