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18 Cards in this Set

  • Front
  • Back
Thiamine - B1
Beri-Beri: high output heart failure (wet), peripheral neuropathy (dry); Wernicke-Korsakoff syndrome: chronic alcoholics, ataxia, ophthalmogplegia, confusion, and confabulation (loss of mamillary bodies)
Riboflavin - B2
Rare because grains are fortified; atrophy of tongue (glossitis), fissures of corner of mouth (cheilosis), dermatitis, corneal ulceration
Niacin - B3
pellagra: dementia, diarrhea, dermatitis; can result from isoniazid, Hartnup disease (AR disorder in tryptophan absorption - Try --> niacin), carcinoid syndrome
Pantothenate - B5
fatigue, allergies, nausea, abdominal pain; more serious reversible cases: adrenal insufficiency hepatic encephalopathy
Pyridoxine - B6
seizures (necessary for Glutamate --> GABA), can result from isoniazid or penicillamine (copper, mercury, cystine toxicity) use
Cobalamine - B12
associate with lack of intrinsic factor; block in purine and thymidine biosynthesis (need FH4) --> megaloblastic anemia and subacute combined degeneration of the spinal cord, causes folate deficiency (need methionine for FH4 production)
impaired dTMP sythesis and DNA sythesis arrest --> megaloblastic anemia; neurotube defects like spina bifida
rare because biotin is synthesized by GI bacteria, may be associated with lonterm antibiotic use and consumption of raw eggs (have avidin that binds and inhibits biotin absorption)
Vitamin C
scurvy: easy bruising, muscular gatigue, soft swollen gums, hemorrhage, anemia
Vitamin A
night blindness, dry eyes --> corneal damage, urinary stones
Vitamin D
rickets (kids): defective mineralization of bone, squared head, chest deformities, spine abnormalities, bowing of legs; osteomalacia (adults): weakening of bone and increased incidence of gross fracture
Vitamin E
rare, may contribute to atherosclerosis and cardiovascular disease
Vitamin K
seen in newborns becaues of lack of GI flora (produce vitamin K), hemorrhage, bleeding diathesis; warfarin antagonizes vitamin K activity
muscle weakness, neurologic defects, abnormal collagen cross linking
goiter and hypothyroidism, uncommon with iodized salt
hypochromic, microcytic anemia
cardiomyopathy (Keshan disease)
growth retardation and impaired wound healing