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124 Cards in this Set

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What are the 5 characteristics of vitamins

Organic compound different from fat, protein and carbohydrates


Component of the diet


Essential in minute amounts for normal physiologic function


It's absence must cause a deficiency syndrome


Synthesized in quantities sufficient to support normal physiologic function

What are the functions of vitamins

Potentiator or cofactors in enzymtic reactions


DNA synthesis


Energy release from nutrients substrates


Bone development


Calcium homeostasis


Normal eye function


Cell membrane integrity


Blood clotting, free radical scavenging


Amino acid and protein metabolism


Nerve impulse transduction

What is a potentiator

Subs that starts a reaction

What are the two main groups of vitamins

Fat soluble


Water soluble

What are the fat soluble vitamins

A


D


E
K

What are the water soluble vitamins

B1


B2


Niacin


B6


Pantothenic acid


Folic acid


B12


Choline


Biotin


Vitamin C

What is B1 also called

Thiamin

What is B2 also called

Riboflavin

What is B6 also called

Pyridoxine

What is B12 also called

Cobalamin

What are the characteristics of fat soluble vitamins

Found in fats and oils and are insoluble in water




Require bile for emulsification and micelles and lipoproteins for absorption and transport




Enter the blood via the lacteals with dietary lipids




Excess can be stored in the liver and adipose tissue



What class of compounds is vitamin A apart of

Retinoids

What are the different types of retinoids

Retinol


Retinal


Retinoic acid

What can be transformed into vitamin A

Carotene


What are the functions of vitamin A

Reproduction


Vision


Cell differentiation and epithelial cell integrity


Immunity


Growth


Antioxidant

What type of vitamin A is needed for reproduction

Retinol

What type of vitamin A is needed for vision

Retinal

What type of vitamin A is needed for cell differentiation and epithelial cell integrity

Retinoic acid

What type of vitamin A is needed for immunity

Retinoic acid

What type of vitamin A is needed for growth

Retinoic acid

What type of vitamin A is needed for antioxidant

Carotene

Vitamin A deficiencies can cause what in Ruminants

Reduced feed intake and growth


Rough hair coat


Lacrimation


Night blindness


Reproductive problems

Vitamin A deficiencies can cause what in dogs and cats

Impaired growth


Reproductive failure


Loss of epithelial integrity



What animal is capable of converting carotenoid to active vitamin A

Dogs

What are sources of vitamin A

Fish liver oils


Milk


Liver


Egg yolk

What is the most toxic vitamin

Vitamin A

What are the cs of vitamin A toxicity

Skeletal malformation


Internal hemorrhaging


Slow growth


Reduced function of liver and kidney


Birth defects

What form of vitamin A can NOT cause toxicity

Beta carotene

How is vitamin D different than all other vitamins

It can be synthesized, with the help of sunlight


Has hormone-like properties

What does vitamin D regulate

Calcium and phosphorus metabolism

What are the two types of vitamin D

Vitamin D2


Vitamin D3

Where is vitamin D2 found

Plants that have been harvested and exposed to UV light

Where is vitamin D3 found

Synthesized by the body when skin is exposed to UV light

What is the function of vitamin D

Normal bone tissue development


Bone tissue maintenance


Homeostasis of the body's calcium and phosphorus pools

Vitamin D deficiencies can cause what in ruminants

Rickets


Tetany and convulsions


Bones fractures easily


Digestive disturbances

Vitamin D deficiencies can cause what in Cats and Dogs

Rickets


Osteomalacia


Nutritional secondary hyperparathyroidism

What are sources of vitamin D

Liver


Some fish


Egg yolk


Sun light

What is osteomalacia

Softening of the bone

What is the second most toxic vitamin to the body

Vitamin D

Vitamin D toxicity can cause what

Excessive levels of calcium in the blood


Calcification of soft tissues


Bone resorption

What are the two groups that compose vitamin E

Tocopherols

Tocotrienols


What are the functions of vitamin E

Antioxidant

Vitamin E works with what mineral to minimize free radical damage to tissues

Se

What vitamin is necessary to regenerate vitamin E

Vitamin C

Vitamin E deficiencies can cause exacerbated whatn disease in ruminants

White muscle disease

What are the cs of white muscle disease

Weakness


Siffness


Deterioration of muscles

Vitamin E deficiencies cause what in cats

Yellow fat

Yellow fat is also called

Pansteatitis

What are the cs of Pansteatitis

Anorexia


Pyrexia


Tenderness


Lumpy fat in abdomen

Is vitamin E toxic

No

What are sources of vitamin E

Wheat germ


Corn and soybean oils

What are the two naturally occurring forms of vitamin K

Phylloquinone (plant origin)


Menaquinone (bacterial origin)

What are the two major forms of vitamin K

Natural


Synthetic

What is the synthetic form of vitamin K

Menadione

What are the functions of vitamin K

Blood clotting mechanisms


Formation of anticoagulant proteins


Formation of bone proteins and ribosomal proteins


Peptides involved in cell growth

What factors in the coagulation process activated by vitamin K

II


VII
IX
X

Vitamin K deficiencies will cause what in dogs and cats

Increased clotting time

Hemorrhage


Ruminants eating what can cause a vitamin K deficiency

Moldy sweet clover

What form of vitamin K is toxic at high levels

Synthetic (menadione)

Vitamin K toxicity can cause what

Anemia


Acute renal failure


Stiffness, colic and laminitis (horses)

What are sources of vitamin K

Leafy green vegetables


Liver


Some fresh meats

B-complex vitamins are _________ soluble vitamins

Water

What is vitamin B1

Thiamine

What is the main role thiamine play

In carbohydrate synthesis

What are thiamine functions

Cofactor for some TCA cycle reactions


Essential role in nerve transmission


Insulin synthesis

What is the TCA cycle

Energy formation cycle

What are glial cells

Nerve assistant cell

Thiamine deficiencies will cause what in ruminants

Polioencephalomalacia


Opisthotonus

What is polioencephalomalacia

Softening of brain tissue

What is opisthotonus

Stargazing

Thiamine deficiencies can cause what in dogs and cats

CNS dysfunction


Anorexia


Weight loss

What are the sources of thiamine

Meat


Wheat germ

What is riboflavin

Vitamin B2

Where does riboflavin get its name

Yellow color


Contains the simple sugar D-ribose

Microbial synthesis of riboflavin occurs where

Large intestines of most species

What are the functions of riboflavin

Cofactor that accepts and transfers H+ from substrates


Important for the generation of ATP


Important in amino acid oxidases

Riboflavin deficiency can cause

CNS dysfunction


Dermatitis

Riboflavin is ________, most is excreted via the feces

Nontoxic

What are the sources of riboflavin

Milk




Organ meats


Whole grains


Vegetables

Niacin is also called

Nicotinic acid

Niacin is closely associated with _______ in cellular oxidation reduction enzyme systems

Riboflavin

Niacin deficiencies can cause what in dogs

Black tongue disease

What are the cs of black tongue disease

Ropy saliva


Foul breath


Discoloration of the tongue

What animal cannot synthesize niacin form tryptophan

Cats

What are the cs of niacin deficiency in cats

Weight loss


Anorexia


Weakness


Apathy


Thick saliva with foul odor

Can niacin be toxic

No

What are the sources of niacin

Meats


Legumes


Grains

What is pyridoxine also called

Vitamin B6

What are the compounds that comprises pyridoxine

Pyridoxine


Pyridoxal


Pyridoxamine

What is the only water soluble vitamin stored in tissues in appreciable quantities

Pyridoxine

What are the functions of B6

Transfer of methyl groups form serine to the methylation cycle


Cofactor for a large number of enzymes used in the metabolism of amino acids

B6 deficiency can cause what in cats and dogs

Microcytic hypochromic anemia

Is B6 toxic

No

What are the sources of B6

Organ meats


Fish


Wheat germ

Pantothenic acid occurs in all ______ __________

body tissues

What are the functions of pantothenic acid

Part of coenzyme A


Fatty acid synthesis


Carbohydrate, fat, and protein metabolism within the citric acid cycle

What is coenzyme A responsible for

ATP formation

Pantothenic acid deficiency can cause what in dogs and cats

Anorexia


Weight loss

Is pantothenic acid toxic

No

What are the sources of pantothenic acid

Organ meats


Egg yolks


Diary products


Legumes

Biotin can be produced by ________ and absorbed form the cecum and colon

Microflora

What are the functions of biotin

Fatty acid, nonessential amino acid, and purine synthesis

Biotin deficiency can cause what in small animals

Dermatitis

Is biotin toxic

No

What are sources of biotin

Eggs


Liver


Milk


Legumes

Folic acid is active int he body as

Tetrahydrofolic acid

Folic acid is synthesized by

Bacteria in the large intestines

What is the function of folic acid

Important role in synthesis of thymidine

Folic acid deficiency can cause what

Not able to produce adequate DNA


Decreased cellular growth and maturation

What are sources of folic acid

Liver


Kidney


Green leafy vegetables

What is cobalamin also known as

vitamin B12

What mineral does cobalamin contain

Cobalt

What vitamin is only synthesized by microorganisms

Cobalamin

What are the functions of cobalamin

Fat and carbohydrate metabolism


Synthesis of myelin

Cobalamin deficiency can cause what

Anemia
Impairment of neurological functioning

What are sources of cabalamin

meat


Fish


Poultry

Choline is synthesized by the body form

The amino acid serine

What are the functions of choline

Donor of methyl units for various metabolic reactions in the body


Precursor for the neurotransmitter substance acetylcholine


Necessary for normal fatty acid transport within cells

Choline deficiencies can cause what

Neurologic dysfuntion


Fatty liver

Cholin toxicity can cause what

Diarrhea

What are sources of choline

Egg yolk


Organ meats


Legumes


Dairy products

What are vitamin C functions

Hydroxylation of the amino acids proline and lysine in the formation of collagen and elastin


Synthesis of acetylcholinesterase


Normal bone formation

Vitamin C deficiencies can cause

Body is unable to synthesize several types of connective tissue



What are sources of vitamin C

Citrus fruits


dark leafy vegetables