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18 Cards in this Set
- Front
- Back
B1
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Thiamine
Wernike-korsakoff syndrome (apathy, memory loss) Wet beriberi (symetrical muscle wasting) Dry beriberi - cardiac failure |
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B2
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Riboflavin
constituent of FMN and FAD |
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B5
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Pantothenic Acid
part of FA synthase complex |
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which vitamin is in the FA synthase complex?
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B5 - Pantothenic acid
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Thiamine
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B1 - beriberis, wernike-korsakoff
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B7
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Biotin
cofactor in carboxylase reactions - pyruvate carboxylase, acetyl CoA carboxylase, propinoyl CoA carboxylase. deficiency caused by eating too many raw eggs. - dermatitis, alopecia, enteritis. |
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Oops I ate too many raw eggs
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B7 deficiency
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B9
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Folate
common deficinecy-- caused by alcoholism. macrocytic megalobalstic anemia. no neurological symptoms, neural tube defects in pregnancy |
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which vitamin is folate?
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B9
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B12
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cobalamin - deficincy = magaloblastic anemia via deficiency of folate. abnormal myelin.
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cobalmin
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B12
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B6
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Pyridoxine, pyridoxal, pyridoxamine: coenzyme = pyridoxal phosphate.
needed for synthesis fo niacin from tryptophan. |
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what does pyridoxal phosphate do?
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turns B6 precursors into B6.
B6 required for transamination and synthesis of niacin from tryptophan. |
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Vit E
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lipid soluable. antioxidant. carried by LDL. decreases oxidation of LDL.
not enough leads to hemolytic anemia, muscle weakness, neurodisfunction |
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I have megaloblastic anemia. What am I missing?
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B12 (cobalamin)... causes secondary deficincy of folate (B9)
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vit D
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osteomalacia in adults, rickets in children.
regulates plasma levels of calcium and phosphorus. |
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vit K
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prolonged use of antibiotics in adults can cause deficiency.
deficiency in newborns causes hemorrhagic disease of the newborn |
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vit A
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preformed: retinoids - too much is toxic to your liver -- skin changes, hair loss, messes with fetus. Think Acutane.
provitamin: beta carotene - can't overdose too little: eye problems. |