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12 Cards in this Set

  • Front
  • Back
how is vitamin A absorbed?
retinyl esters broken down to free retinol in small intestine
-requires bile,degestive enzymes, micelles
-once absorbed retinyl esters reformed in intestinal cells
-carotenoids absorbed intact and converted to retinols in intestine cells
Excess vitamin A affects what other vitamin absorption?
Vitamin K
Toxicity of vitamin A
if pregnant abort or birth defects
-kidney disease
Vitamin D deficiency and toxicity?
deficiency: rickets/osteolamacia
-toxicity: hypercalcemia - ca. dep. in kidneys, heart , vessels, retardation, facial changes, aorta narrowing

- derived from cholesterol
-D3 formation in skin from sun
-D2 from food
absorption of vitamin D
-D3 converted in skin
-D2 metabolized in liver with 25-OH and then 1,25 OH in kidney which is active form
Vitamin E (aka____)
functions?
what foods?
Too much inhibits what?
-Tocopherols
-FUnctions: Antioxidant, protects cell membrane
-Foods: plant oils, wheat germ, peanuts, nuts, seeds (plant stuff)(no meat)
-too much inhibits vK absorption
Vitamin K (2 types?)
one type synthesized somewhere by what and where?
delivery?
FUnctions:
deficiency:
-K1 - phyloquinones (plants)
-K2 - menaquinones (meat, int bact)
-menaquinones synthesized by intestinal bacteria and absorbed in colon
-Delivered via lymphatic system
- functions: coagulation (prothrombin synthesis)
-resistant to cooking losses
-deficiency: excess bleeding, antiobiotics detroy int bact that make menaquniones cause deficiency
B1 (______)
Functions(coenzyme)
Defiency
FOods:
-thiamin
-functions: thiamin pyrophosphate (TPP)
-coenzyme in metabolism of carbs, branch AA, and pentoses
-carrier of active aldehyde
-role in synthesis of neurotransmitters
-deficiency: where polished rice only food. peripheral neuropathy
-dry beriberi- weakness, nerve degeneration
-wet beriberi - edema and heart problems
-white bread, pork, hot dogs,enriched grains,whole wheat
B2 (____)
Coenzymes?
Functions?
Deficiency?
Foods:
-Riboflavin
-FMN,FAD
-Functions: in oxidation reduction rxns(CAC, beta oxidation of fatty acids
-deficiency: ariboflavinosis; long term users of phenobarbitol.
-also causes glossitic, cheilosis, stomatitis, dermatitis (orally)
-milk products, enriched grains, liver
Niacin (___)
Coenzymes
FUnctions:
Defiency
foods?
B3 (nicotinic acid)
-NAD, NADP
-NADH and NADPH in ox redox rxns
-catabolic rxns: glycolysis and CAC
-anabolic rxns: fatty acid synthesis (NADPH)
-pellagra: diarrhea, dementia, dermatitis
-alcoholics and untreated corn susceptible
-shrooms, enriched grains, beef, chicken, turkey, fish
tryptophan can be synthesized to what vitamin?
Niacin (B3)
Pantothenic acid
functions?
Absorption
Foods?
B5
-part of coenzyme A for energy metabolism
-metabolism of carbs, fat, protein, and alcohol
-consumed as coenzyme A in diet and released in digestion
-absorbed as pantothenic acid in small int.
-everywhere, meat, milk, grains, liver, peanuts, shrooms