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12 Cards in this Set
- Front
- Back
how is vitamin A absorbed?
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retinyl esters broken down to free retinol in small intestine
-requires bile,degestive enzymes, micelles -once absorbed retinyl esters reformed in intestinal cells -carotenoids absorbed intact and converted to retinols in intestine cells |
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Excess vitamin A affects what other vitamin absorption?
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Vitamin K
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Toxicity of vitamin A
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if pregnant abort or birth defects
-kidney disease |
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Vitamin D deficiency and toxicity?
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deficiency: rickets/osteolamacia
-toxicity: hypercalcemia - ca. dep. in kidneys, heart , vessels, retardation, facial changes, aorta narrowing - derived from cholesterol -D3 formation in skin from sun -D2 from food |
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absorption of vitamin D
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-D3 converted in skin
-D2 metabolized in liver with 25-OH and then 1,25 OH in kidney which is active form |
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Vitamin E (aka____)
functions? what foods? Too much inhibits what? |
-Tocopherols
-FUnctions: Antioxidant, protects cell membrane -Foods: plant oils, wheat germ, peanuts, nuts, seeds (plant stuff)(no meat) -too much inhibits vK absorption |
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Vitamin K (2 types?)
one type synthesized somewhere by what and where? delivery? FUnctions: deficiency: |
-K1 - phyloquinones (plants)
-K2 - menaquinones (meat, int bact) -menaquinones synthesized by intestinal bacteria and absorbed in colon -Delivered via lymphatic system - functions: coagulation (prothrombin synthesis) -resistant to cooking losses -deficiency: excess bleeding, antiobiotics detroy int bact that make menaquniones cause deficiency |
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B1 (______)
Functions(coenzyme) Defiency FOods: |
-thiamin
-functions: thiamin pyrophosphate (TPP) -coenzyme in metabolism of carbs, branch AA, and pentoses -carrier of active aldehyde -role in synthesis of neurotransmitters -deficiency: where polished rice only food. peripheral neuropathy -dry beriberi- weakness, nerve degeneration -wet beriberi - edema and heart problems -white bread, pork, hot dogs,enriched grains,whole wheat |
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B2 (____)
Coenzymes? Functions? Deficiency? Foods: |
-Riboflavin
-FMN,FAD -Functions: in oxidation reduction rxns(CAC, beta oxidation of fatty acids -deficiency: ariboflavinosis; long term users of phenobarbitol. -also causes glossitic, cheilosis, stomatitis, dermatitis (orally) -milk products, enriched grains, liver |
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Niacin (___)
Coenzymes FUnctions: Defiency foods? |
B3 (nicotinic acid)
-NAD, NADP -NADH and NADPH in ox redox rxns -catabolic rxns: glycolysis and CAC -anabolic rxns: fatty acid synthesis (NADPH) -pellagra: diarrhea, dementia, dermatitis -alcoholics and untreated corn susceptible -shrooms, enriched grains, beef, chicken, turkey, fish |
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tryptophan can be synthesized to what vitamin?
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Niacin (B3)
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Pantothenic acid
functions? Absorption Foods? |
B5
-part of coenzyme A for energy metabolism -metabolism of carbs, fat, protein, and alcohol -consumed as coenzyme A in diet and released in digestion -absorbed as pantothenic acid in small int. -everywhere, meat, milk, grains, liver, peanuts, shrooms |