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49 Cards in this Set
- Front
- Back
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what family is the rhiniovirus
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picorna
small naked ichosohedral |
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what are the characteristics of the rhinovirus
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115 serotypes, acid labile, cytopathic, optimum replciation at 33 vs37 C
limited to upper respiratory infections. |
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What does the high number of serotypes of rhinovirus mean
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that even if u gain immunity to one ur still vulnerable to others this is why people get colds so often
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what is the characteristics of the cornavirus
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+ssRNA lipid enveloped
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what are the two major causes of the common cold
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rhino virus
corona virus |
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should you prescribe antibiotics for the common cold
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no, the vast majority are caused by viruses
group B strep is the only one that causes cold like symptoms and only account for 10% of infection |
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how is the virus transmitted
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human to human vir respiratory secretions
2-3 day incubation |
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when is the rhiniovirus most common
what about corona |
rhino year round
corona winter |
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what is the treatment for common cold
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antihistimes over the counter not very good mainly just have to live with it
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is there any immunity to virus
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not really secretory IgA protects but is not life long
this is why there are no vaccines for virus |
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what are the properties of the adenoviruses
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naked icosahedral capsid
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how are adenoviruses transmited
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rispiratory and fecal oral
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what are the symptoms of the infection in adenovirues
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GI tract infection is asymptomatic but infection of respriatory tract is symptomatics
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what does adenovirus cause
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acute respirtitory disease
mild upper respiratory tract syndromes(tonsils and adenoids of children) |
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what are some characteristics of the acute respirtatory disease cause by adenovirus
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two types 4, and 7
most common in winter, and military type 14 common in young adults causes penmonia severe and sometimes fatal in childrean |
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what adeno virus types cause what
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acute respiratory disease-type 4,7,14
pnemonia- type 3, 7(kids) 4,7 (adults) mild upper respiratry tract syndomes-1,2,5,6 pharyngoconjuctiveal fever-summer infection kids, types 3,7 |
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what are the nonrespiratory adenoviral syndrome
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epedimec keratoconjuctivitis: types 8, 37 and 19
acute hemorrhagic cystitis: young boys types 11, 21 cervicitis and urethritis: type 37 gastroenteritis: infants types 40, 41, and 31 pediatric transplant recipients: adenovirus infection associated with higher rate of complicasion and organ rejection |
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what does paramyxoviridae cause
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measles
mumple respiratory syncytial virus parainfluencza |
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what is a unique formation in the paramyxociridae
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syncytia formation
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how are measle mumps rubella spread
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respiratory route droplet spread and contaminated surface
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when is the peak time for measles mumps rubella
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winter/spring
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can measles mumps rubella be prevented
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yes there are vaccines(live attenuated) and one time getting the disease provide life long immunity
6months immunity in newborns |
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what are the 4 Cs of measles
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cough
coryza,-rash on face that coelese conjunctivitis Kopliks spots -grains of sand in mouth diagnostic |
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what are some complications of measles
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fatal pneumonia
otitis media post infectino encephalomyelitis subacute scelersing panencephalitis(rare) |
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what are the symptoms of mumps
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swollen salivary glands
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what are the complication of mumps
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orchitis
oophoritis meningitis hearing loss arthritis acute pancreatitis |
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what does RSV cause
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bronchiolitis pneumonia
winter spring |
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parainfluenza types 1 and 2 cause flue when
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around fall
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how is RSV, parainfluenza and adenoviruses diagnosed
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antigen detection kit assay
RT-PCR and PCR based test of respiratory specimen to detect |
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how is measles treated
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vit A
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what are the properties of rubella
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lipid enveloped icosahedral capsid with + ssRNA
humna to human transmission |
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what are the symptoms of rubella
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mild measle like symptoms rash on face spotty
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what is the major risk of rubella
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congenital rubella syndrome
deafness visual defects congental heart defects |
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how is congenital rubella syndrome diagnosed
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anti rubbella IgM antibody capture ELISA from newborn serum
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what are hemaglutinin and neuraminidase
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membrane glycoprotiens that are used for vaccines and constantly undergo antigenic drift
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what are the 3 types of influenza
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type A-(many subtypes)in human, mammals and birds causes seasonl epidemcis almost every year
Type B- only in human, causes epidemics type C - infects human but not clinically important |
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what are the only types of influenzae A that are transmited human to human
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H1-H3
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what is the major cause of serious lower respiratory dieases
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influenza A and B
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what are the symptoms of influenza brought on by
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TNF - alpha inflammatory
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what are the major symptoms of influenza
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fever, chills, aches, pnemonia
NO NAUSA |
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how is influenza diagnosed
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nucleic acid specific assays
rapid antigen capture ELISA useful for defining antiviral treatment. |
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what is the peak month for influenza
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february
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what are the major antivirals used for influenza
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amantadine and rimantadine block uncoatin and nuclear transport
neuramindidase inhibitors(prophalaxis) block the final stages of virion budding |
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who should not get flu vaccine
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6mo younger
egg allergy really bad |
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what are upper resp. symptoms
lower? |
upper-sneezing, coughing,
lower- wheezing |
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when is the most common time for respriratory disease
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dec, jan, feb
mainly RSV |
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6 mo URI with FEVER and wheezing ?
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bronchiolitis probably RSV
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two yo with barking cough URI spasmodic cough
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laryngotracheobronchitis
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12 yo with sudden fever headache, myalgias cough
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acute influencza virus
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