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50 Cards in this Set
- Front
- Back
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What are four dsDNA virus families?
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1) Herpes 2) Adeno 3) Pox 4)Hepadna
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What is an example of a ssDNA virus?
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Parvo
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What are three examples of +ssDNA virus familes?
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1) Retro 2)Picorno 3) Toga
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What is an example of a dsRNA virus family?
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Reo
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What are two examples of -ssRNA virus familes?
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1) Paramyxo 2)orthomyxo
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What is the difference between a structural and non-structural proteins found in virions?
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Structural protines are found in the virion and include capsid and envelope glycoproteins,; non-structural proteins are produced in virus-infected cells but are not packaged into the new virions, examples include DNA and RNA polymerases
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To what family does the influena virus belong?
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Orthomyxo
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To what family do the HIV and HTVL virions belong?
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Retro
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To what family does the hepatitis B family belong?
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hepadna
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Describe the structure of the Herpes virus including the nature of it's polymerase
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Herpes is an enveloped icosohdral virus with non-structural DNA dependant DNA polmyerase
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What is the structure of the Adeno virus?
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naked icosohedral
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Describe the replication machinery of the Pox virus
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Pox has a structural DNA dependandt RNA polymerase and also has a non-structural DNA dependant DNA polymerase
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Describe the structure of the hepatits B virus and include the nature of it's replication machinery
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Hepatitis B is a lipid-envelope icosohedral with a structural RNA dependant DNA polymerase (i.e. reverse transcriptase)
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Describe the structure of the Parvo virus
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naked icosohedral
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What are four dsDNA virus families?
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1) Herpes 2) Adeno 3) Pox 4)Hepadna
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What is an example of a ssDNA virus?
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Parvo
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What are three examples of +ssDNA virus familes?
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1) Retro 2)Picorno 3) Toga
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What is an example of a dsRNA virus family?
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Reo
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What are two examples of -ssRNA virus familes?
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1) Paramyxo 2)orthomyxo
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What is the difference between a structural and non-structural proteins found in virions?
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Structural protines are found in the virion and include capsid and envelope glycoproteins,; non-structural proteins are produced in virus-infected cells but are not packaged into the new virions, examples include DNA and RNA polymerases
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To what family does the influena virus belong?
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Orthomyxo
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To what family do the HIV and HTVL virions belong?
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Retro
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To what family does the hepatitis B family belong?
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hepadna
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Describe the structure of the Herpes virus including the nature of it's polymerase
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Herpes is an enveloped icosohdral virus with non-structural DNA dependant DNA polmyerase
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What is the structure of the Adeno virus?
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naked icosohedral
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Describe the replication machinery of the Pox virus
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Pox has a structural DNA dependandt RNA polymerase and also has a non-structural DNA dependant DNA polymerase
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Describe the structure of the hepatits B virus and include the nature of it's replication machinery
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Hepatitis B is a lipid-envelope icosohedral with a structural RNA dependant DNA polymerase (i.e. reverse transcriptase)
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Describe the structure of the Parvo virus
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naked icosohedral
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What is the structutre of the Picorno virus?
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naked icosohedral
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What is the structure of the Toga virus?
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enveloped icosoheral
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What is the structure of the HTVL retro virus?
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enveloped icosahedral
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What is the structure of the retro virus HIV?
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icosohedral like
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What is a +ssRNA virus?
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A virus that uses single stranded RNA to manufacture RNA or DNA with the help of either a RNA dependant RNA polymerase or a RNA dependant DNA polyermase
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What is a -ssRNA virus?
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A virus that cannot use it's RNA genome as a template for making new genetic material
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Describe the genome of the Reo virus family as well as the replication machinery
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Reo family has a segmented genome with a structural RNA dependant RNA polymerase
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Describe the genome of the orthomyxo family
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segmented genome
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What is a virion?
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The complete infectious particle of the virus
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What is a nucleocapsid?
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The nucleic acid genome and the capsid
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What is a structural protein?
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Viral genome-encoded protein species is present in the virion
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What is a non-structural protein?
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The viral genome-encoded protein species is only present in the infected cells and NOT present in the virion
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What is a segmented genome?
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A genome that is in dictinct pieces
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What is a capsomer and why is it important?
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A capsomer is the morphologicalprotein subunit that is visible by EM that helps define what family the virus is in
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What is a helical nucleocapsid?
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Structure formed by protein-RNA interactions that fold into a circular stairway giving a helical structure; they must be surrounded by a viral envelope to make tehe infectious particle complete
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From what is the lipid envelope a virion derived?
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The host cell membrane; it contains viral glycoproteins
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Why are some virus envelopes fragile?
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So they can fuse easily with the cell membrane of the host
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What sort of virions can survive the passage through the acid stomach?
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Naked icosohedral; stomach acid removes the lipid enveloped of enveloped virions, rendering them non-infecetious
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How are lipid enveloped virions transmitted?
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Respiratory droplets
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What are the important antigens for lipid-envelope virions?
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The immune system recognizes the viral envelope glycoproteins
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What are the important antigens for the naked icosahedral virions?
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Viral capsid proteins
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Are antibodies to internal viral proteins protective?
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No, but they can be used for immulogical assays
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