Virus Details

Front 1

Which virus has hemagglutinin/neuraminidase, the attachment protein, as the major antigenic determinant, which is responsible for the adsorption of the virus to sialic acid-containing cellular receptor molecules?

Back 1

Paramyxovirus

Front 2

Which virus of the Paramyxovirus family has agglutination properties but no Neuraminidase activity?

Back 2

Measles

Front 3

Which virus of theParamyxovirus family has no detectable hemagglutination or neuraminidase (has G protein)?

Back 3

RSV

Front 4

Which members of the Paramyxovirus family have both hemagglutination and neuraminidase activity?

Back 4

Parainfluenza and Mumps

Front 5

Which family of viruses causes syncytium formation (cell-to-cell fusion)?

Back 5

Paramyxovirus

Front 6

Which virus not only forms syncytia, but also forms eosinophilic inclusions in the cytoplasm and nucleus?

Back 6

Measles

Front 7

Which viral proteins are thought to play a major role in Paramyxoviruses in bringing the assembled ribonucleoprotein core to the appropriate site on the plasma membrane to form the budding virion?

Back 7

M protein

Front 8

What is the tropism of the Measles virus?

Back 8

tracheal and bronchial epithelial cells, lymphoid organs and tissues

Front 9

What cellular receptor/s is/are used by Measles?

Back 9

CD46 and CD150SLAM

Front 10

SSPE is caused by a mutant measles virus that has abnormal expression of which protein?

Back 10

M protein

Front 11

What time of year are Parainfluenza type 1 & 2 infections most common?

Back 11

autumn

Front 12

What time of year are Parainfluenza type 3 infections most common?

Back 12

all year round

Front 13

What type of viruses are Nipah and Hendra (human is accidental host; outcome is severe)?

Back 13

Paramyxovirus

Front 14

What is the major capsid protein of Rotaviruses and determines the group designation?

Back 14

VP6 inner capsid protein

Front 15

Which protein in Rotaviruses induces formation of neutralizing antibodies, does attachment and entry, is usually the most abundant outer capsid protein, and determines the serotype?

Back 15

VP7

Front 16

Which protein in Rotaviruses is protease sensitive, forms spikes, cell attachment, is the determinant of virulance and serotype, induces formation of neutralizing antibodies, and does hemagglutination?

Back 16

VP4

Front 17

Where does the uncoating of Rotavirus take place?

Back 17

lysosomes

Front 18

Which virus is acid, ether, and heat stable?

Back 18

Norovirus

Front 19

Which virus is small, ssRNA, positive sense, polyadenylated, and encodes three open reading frames?

Back 19

Norovirus

Front 20

Which virus is nonenveloped, has icosahedral symmetry, starlike surface structure, and plus-sense ssRNA?

Back 20

Astrovirus

Front 21

Which virus has plus-stranded RNA which codes for subgenomic RNA, is enveloped, and whose infection may induce cell fusion?

Back 21

Coronavirus

Front 22

Which virus has E2-glycoprotein-mediated fusion?

Back 22

Coronavirus

Front 23

What type of virus are SARS and MERS?

Back 23

Coronavirus

Front 24

Which virus is non-enveloped, icosahedral, linear dsDNA, w/ a terminal protein attached at the 5' end?

Back 24

Adenovirus

Front 25

Which virus's attachment is mediated by fiber proteins w/ "knobs", enter the cell via receptor-mediated endocytosis in a clathrin-coated vesicle, and inhibits cellular macromolecular synthesis and mRNA transport through toxic pentons and fibers?

Back 25

Adenovirus

Front 26

Which virus must induce the cell to enter S-phase of the cell cycle (E1A and E1B)?

Back 26

Adenovirus

Front 27

Which virus is nonenveloped, has icosahedral symmetry, an RNA genome, has capsid proteins (including VP4), protomers and pentamers, w/ each virion consisting of 12 pentamers?

Back 27

Picornavirus

Front 28

Which virus is single stranded, positive sense RNA?

Back 28

Picornavirus

Front 29

Which virus uses the cell receptor erythrocyte P antigen?

Back 29

Parvovirus

Front 30

Which virus is highly fetal tropic, and has the highest levels of replication occur in erythroid progenitor cells?

Back 30

Parvovirus

Front 31

Which virus is the only DNA virus that is nontransforming and actually is somewhat protective against transformation?

Back 31

Parvovirus

Front 32

In which virus is the early ORF of the genome sufficient for inducing cellular transformation?

Back 32

Papillomavirus

Front 33

Which virus has E5, E6, E7 oncogenes?

Back 33

Papillomavirus

Front 34

Which virus has Dane particles, the largest particles produced and the infectious particle?

Back 34

Hepatitis B (Hepadnavirus)

Front 35

Which virus has a protein kinase and a viral polymerase associated w/ the virion?

Back 35

Hepatitis B (Hepadnavirus)

Front 36

Which viruses encode a large array of enzymes for nucleic acid metabolism, synthesize viral DNA and assemble capsids in the nucleus, cause irreversible destruction of the infected cell through production of infectious progeny, and can remain latent in their natural hosts?

Back 36

Herpesvirus

Front 37

Which virus subfamily is classified on a basis of a variable host range, short reproductive cycyle, rapid spread in culture, efficient destruction of infected cells, and establishment of latency in primarily sensory ganglia?

Back 37

alphaherpesvirinae

Front 38

Which virus subfamily is classified on the basis of restricted host range, long reproductive cycle, slow progression of infection in culture, infected cells become enlarged and carrier cultures readily established, establishment of latency in secretory glands, lymphoreticular cells, kidneys and other tissues?

Back 38

betaherpesviridae