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25 Cards in this Set
- Front
- Back
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List the 6 stages of viral illness:
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1. Incubation
2. Prodrome 3. Onset 4. Acute 5. Recovery 6. Convalescance |
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When is viral material detectable by tests in these stages?
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Prodrome = occasionally
Onset = Frequently Acute = Frequently |
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So the virus is directly detectable when the symptmos are:
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worst - onset and acute phase.
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When is specific antibody demonstrable in the illness?
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Acute phase - frequently
Recovery/convalescent - usually. |
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When is antibody NOT detectable?
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during Incubation and Prodrome.
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If a person tested positive for antibody during the incubation phase, what would this tell you?
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The person was previously vaccinated or naturally infected.
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List the 4 types of viral infections:
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1. Acute
2. Latent 3. Chronic 4. Prion |
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What is the fate of viruses in each infection type?
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Acute: eliminatd, doesnt persist
Latent: not eliminated; persists for months, years, or even life. Chronic: Virus persists Prion: Virsus persists. |
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What are the characteristics of an acute viral infection?
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1. Short incubation
2. Can recover virus but only during acute and onset. |
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What are the recovery qualities of Acute viral infections?
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1. Recovery COMMON
2. Confers resistance to future reinfections and w/ similar viruses. |
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What type of course does a latent virus generally follow?
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Primary infection = acute
During latency, illnes ranges from relapse to remission. |
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Compared to the acute virus only detectable in O and A phases, when is a Latent virus detectable?
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During Primary and Relapsing phases; not during remission.
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Immunologically, what causes a latent virus to exist?
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The host's immune system is ineffective in preventing relapse.
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Name 2 examples of an Acute virus:
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1. Variola
2. Poliomyelitis |
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Name 3 examples of a Latent virus:
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1. HSV
2. Varizella-Zoster 3. CMV |
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What is the general description of the disease course of chronic viruses?
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Incubation periods vary in length, so does the rest.
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When, during chronic infections, is virus recoverable?
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Regularly - it persists all through the infection.
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What differentiates a chronic from latent infection?
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The host's immunity is demonstrable in both, but does not even influence a chronic.
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Give 3 examples of a chronic virus:
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1. Rubella
2. CMV 3. Hep B/C |
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What are the characteristics of a prion infection?
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1. Incubation for months-years
2. Disease is relentless, progressive, and lethal. |
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When is prion detectable in such an infection?
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Both before onset and throughout the disease course.
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what were prions called previously?
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slow viruses
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what is the typical host immune response to a prion?
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Unpredictable! sometimes absent, weak, exaggerated, constant, or unconstant.
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Name 4 examples of Prions:
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1. Kuru
2. Progressive multifocal leukoencephalpathy 3. Subacute sclerosing panencephalitis 4. Creutzfeldt Mad cow disease |
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How is a prion different from a virus, structurally?
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Just protein; not genome.
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