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22 Cards in this Set

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Herpesviruses
Enveloped, DS Linear DNA

HSV-1 = Oral lesions, keratoconjuctivitis, most common cause of sporadic encephalitis in the US
HSV-2 = genital lesions
VZV(HSV-3)= chickenpox, zoster(shingles)
EBV(HSV-4)= mononucleosis, Burkitt's Lymphoma
CMV(HSV-5)= infection in immunosuppressed patients(AIDS retinitis), especially transplant recipients; congenital defects
HHV-6 = roseola(exanthem subitum)
HHV-7 = clinically insignificant
HHV-8 = Kaposi's Sarcoma-associated herpes virus(KSHV)
Hepadnavirus
enveloped, DS partial circular

HBV - acute or chronic hepatitis, vaccine available(contains HBV surface antigen).

Notably, NOT a retrovirus but has a REVERSE TRANSCRIPTASE and is necessary for its viral life cycle.
Adenovirus
NOT enveloped, DS linear

Febrile pharyngitis - sore throat; acute hemorrhagic cystitis
pneumonia,
conjunctivitis - "pink eye"(watery)
Parvovirus
NOT enveloped, SS NEGATIVE sense linear DNA(smallest DNA virus)

B19 virus - aplastic crises in sickle cell disease, "slapped cheeks" rash in children(Erythema Infectiosum or Fifth disease), RBC destruction in fetus leads to hydrops fetalis and death, pure RBC aplasia and rheumatoid arthritis-like symptoms in adults.
Papillomavirus
NOT enveloped, DS circular

HPV - warts(1,2,6,11), CIN, cervical cancer(16,18,31,33) vaccine available but does NOT guard against all serotypes.
Polyomavirus
NOT enveloped, DS circular DNA

JC Virus - Progressive Multifocal Leukoencephalopathy(PML) in HIV
Poxvirus
Enveloped, DS linear(largest DNA virus)

Smallpox, Vaccinia(cowpox strain which vaccine for smallpox derived from),
EASILY OVERLOOKED DISEASE BELOW
***Molluscum contagiosum - flesh colored dome lesions with central dimple
Reoviruses
NOT enveloped, DS(DOUBLE STRANDED) RNA, Linear segmented(10-12 segments), capsid is icosahedral(double)

Coltivirus, Rotavirus
Picornavirus
NOT enveloped, SS + linear RNA, icosahedral capsid.

Poliovirus, Echovirus, Rhinovirus, Coxsackievirus, Hepatitis A Virus
PERCH
Poliovirus - polio-sarlk/savin vaccines -- IPV/OPV
Echovirus - aseptic meningitis
Rhinovirus - common cold
Coxsackievirus - aseptic meningitis, herpangina/hand,foot,mouth disease and myocarditis
HAV - acute viral hepatitis
Hepevirus
NOT enveloped, SS + linear RNA, Icosahedral capsule

Hepatitis E Virus
Calicivirus
NOT enveloped, SS + linear RNA, icosahedral

Norwalk virus - viral gastroenteritis
Flavivirus
Enveloped, SS + linear RNA, icosahedral capsule

Hepatitis C Virus, Yellow fever*, Dengue*, St Louis Encephalitis*, West Nile Virus*

* = arbovirus, transmitted by arthropods(mosquitos/ticks)
Togavirus
Enveloped, SS + linear RNA, icosahedral capsule

Rubella(German measles), Eastern equine encephalitis*, Western Equine Encephalitis*

* = arbovirus, transmitted by arthropods(mosquitos/ticks)
Retrovirus
Enveloped, SS + linear RNA, icosahedral
NOTABLY HIV is DIPLOID genome. Meaning it has 2 single strands in the capsid.
Has reverse transcriptase to incorporate into genome.

HIV, HTLV(T-cell leukemia)
Coronavirus
Enveloped, SS + Linear RNA, Helical capsid

Coronavirus
Orthomyxovirus
Enveloped, SS - linear RNA, segmented(8), Helical capsid

Influenza virus
Paramyxovirus
Enveloped, SS - linear RNA, non-segmented, helical capsid

PaRaMyxovirus: Parainfluenze(croup), RSV(bronchiolitis in babies;Rx - ribavirin), Rubeola(Measle), Mumps
Rhabdovirus
Enveloped, SS - linear RNA, helical capsid

Rabies
Filovirus
Enveloped, SS - linear RNA, helical capsid

Ebola/Marburg hemorrhagic fever - often FATAL
Arenavirus
Enveloped SS - circular RNA, segmented(2), helical capsid

LCMV - lymphocytic choriomeningitis virus
Lassa fever encephalitis - spread by mice
Bunyavirus
Enveloped, SS - circular RNA, segmented(3), helical capsid

California encephalitis*, Sandfly/Rift Valley fevers*, Crimean-Congo hemorrhagic fever*, Hantavirus(hemorrhagic fever, pneumonia)

* = arbovirus, transmitted by arthropods(mosquitos/ticks)
Deltavirus
Enveloped, SS - circular RNA, Helical capsid

Hepatitis D virus
Requires Hep B coinfection or must be a superinfection on pre-existing Hep B.