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19 Cards in this Set
- Front
- Back
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Herpes (HSV)
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Icosahedral, Enveloped, dsDNA - nucleus replication (3 rounds of transcription), portal of entry = epithelium, target = nerves, latency in neurons as an episome
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Adenovirus
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Icosahedral, Naked, dsDNA - nucleus replication (2 rounds of transcription), Antereceptors
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Papilloma (HPV) (& Polymomavirus)
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Icosahedral, Naked, dsDNA - nucleus replication (3 rounds of transcription), infect basal cells, replicate in spinosum, capsid/shed in corneum
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Poxvirus
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Complex, Enveloped (from Golgi), dsDNA - cytoplasm replication, makes mRNA in capsid upon entry
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Parvovirus
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Slapped Cheek (5th Disease), Icosahedral, Naked, ssDNA, receptor-mediated endocytosis, can cause hydrops fetalis (causing a spontaneous miscarriage), only DNA virus not capable of transformation
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Picornavirus
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Polio & Hep A (HAV), Icosahedral, Naked, (+) RNA - full genome, IRES for ribosome binding, forms a polyprotein
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Flavivirus
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Hep C (HCV), Icosahedral, Enveloped, (+) RNA - full genome, forms a polyprotein
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Coronavirus
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SARS & MERS, Helical, enveloped, (+) RNA - subgenomic
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Togavirus
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Icosahedral, Enveloped, (+) RNA - subgenomic
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Calcivirus
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Hep E (HEV), Icosahedral, Naked, (+) RNA - subgenomic
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HIV
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Icosahedral, Enveloped, retrovirus, diploid, able to cause transformation, high frequency of homologous recombination with other viruses
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Paramyxovirus
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RSV/Measles/Mumps, Helical, Enveloped, (-) RNA - nonsegmented, CPE = syncytium (caused by "fusion protein on envelope), portal of entry = upper resp, target = epithelium / lymphatics
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Rhabdovirus
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Rabies, Helical, Enveloped, (-) RNA - nonsegmented
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Filovirus
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Ebola, Helical, Enveloped, (-) RNA - nonsegmented
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Orthomyxovirus
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Influenza A, Helical, Enveloped, (-) RNA - segmented (7-8 segments), receptor-mediated endocytosis, M2 H+ channel dissociates RNA from envelope (target of antivirals), reassortment causes antigenic shift
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Bunyavirus
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Arthropod (mosquito/ticks/fleas/rodents)-borne diseases, Helical, Enveloped (but not matrix proteins), (-) RNA - segmented (3 segments), Symptoms = encephalitis, Hemorrhagic fever, Hantavirus Pulmonary Syndrome
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Rotovirus (aka Reovirus)
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Gastroenteritis in kids, icosahedral, Naked, dsRNA
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Hepadenavirus
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Hep B (HBV), Icosahedral, Enveloped, Relaxed Circular Partially Duplexed DNA
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Arenavirus
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Lymphocytic Choriomeningitis (LCM) & Hemorrhagic Fever (Lassa), Icosahedral, Enveloped, Ambisense RNA, Receptor-mediated endocytosis, rodent vectors in tropics, persistent infections
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