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28 Cards in this Set
- Front
- Back
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What disease does reovirus cause?
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Colorado tick fever
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What is the most important member of the hepeviridae?
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HEV
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What is the most important member of the calciviridae?
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Norwalk virus
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What are the important members of the flaviviridae?
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HCV
Arboviruses: Yellow fever, Dengue, West Nile, St. Louis encephalitis |
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What are the important members of the togaviridae?
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Rubella
Some arboviruses |
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What are the important members of the retroviridae?
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HIV
HTLV |
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What are the important members of the coronaviridae?
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Coronavirus
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What are the important members of the orthomyxoviridae?
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Influenza
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What are the important members of the paramyxoviridae?
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Parainfluenza
RSV Measles Mumps |
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What are the important members of the rhabdoviridae?
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Rabies
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What are the important members of the filoviridae?
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Hemorrhagic fever viruses:
Ebola Marburg |
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What are the important members of the bunyaviridae?
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California encephalitis
Hantavirus |
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What are the important members of the deltaviridae?
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HDV
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What unique feature of viral translation is shared by all enteroviruses?
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They are translated as one long polypeptide, then cleaved into smaller viral proteins
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What is the method of transmission of yellow fever?
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Aedes mosquito
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What are the classic S/Sx of yellow fever?
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High fever with black vomitus and jaundive
Councilman bodies in the liver |
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What is the classic manifestation of rotavirus infection?
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Voluminous, watery diarrhea with villous destruction
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What are the classic S/Sx of rubella?
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"3-day measles"
Fever, postauricular lymphadenopathy, and a very fine rash that begins at the head and moves downward |
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What protein is expressed by all paramyxoviridae?
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"Surface F protein" ---> causes fusion of adjacent respiratory epithelial cells ---> syncytia formation
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Which Mab is used in RSV
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Palivizumab ---> neutralization of RSV "surface F protein"
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What are the possible sequelae of measles?
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Subacute sclerosing panencephalitis
Giant cell pneumonia |
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What are the classic S/Sx of measles?
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Coryza/conjunctivitis/cough/Koplik spots
Erythematous, maculopapular rash that starts on the face and spreads downward |
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What are the classic S/Sx of mumps?
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Fever with parotitis, orchitis, and aseptic meningitis
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What is the feared complication of mumps infection?
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Sterility in postpubertal teens
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How long is the incubation period for rabies?
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Very long (weeks to months) ---> allows for effective vaccination after virus exposure
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What are the classic S/Sx of rabies?
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Fever, malaise ---> agitation, photophobia, hydrophobia ---> paralysis, coma ---> death
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What is the classic histology associated with rabies?
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"Negri body" inclusions and bullet-shaped nucleocapsids
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What are the classic S/Sx of dengue fever?
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Fever/HA/myalgias ---> rash ---> severe hemorrhage ---> shock ---> death
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