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25 Cards in this Set
- Front
- Back
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4 respiratory virus families
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influenza
parainfluenza RSV metapneumovirus |
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flu internal Ags (2)
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nucleocapsid protein (NP)
matrix (M) |
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flu external Ags (2)
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HA
NA |
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flu types are named ___ after their ___
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A/B/C
NP Ag |
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flu A hosts
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humans
horses pigs birds |
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flu B hosts
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humans
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flu C hosts
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humans
pigs |
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flu ___ but not flu ___ can cause pandemics, because the latter has ___
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A
B only humans as a host, so no Ag shift |
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Abs are developed against ___ and ___ Ags, but anti-___ are more important
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HA
NA HA |
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systemic symptoms of respiratory viruses are due to
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necrosis of pulmonary cells
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flu vaccine is ___. efficacy is ___%
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inactivated virus
70 |
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___ can be given prophylactically for flu ___. they work by inhibiting ___
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amantidine
rimantidine A ion channel |
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flu drugs (2). they work by inhibiting ___
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oseltamivir
zanamivir NA |
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paramyxovirus Ags
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HN
F |
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HN protein actions (2)
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HA
NA |
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F protein does
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cell fusion -> giant cells
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because ___, parainfluenza can't cause pandemics
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its genome is unsegmented
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major complaint due to parainfluenza is ___
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croup in children
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parainfluenza drug
it is a ___. |
ribavirin
synthetic nucleoside |
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RSV infection is common in ___
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children
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RSV drug
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ribavirin
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measles is in the ___ family
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paramyxoviridae
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early measles infection is characterized by ___
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koplik spots
respiratory symptoms |
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SSPE is ___ and occurs ___ after measles infection
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subacute sclerosing panencephalitis
5-15 years |
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___ is a rare complication of measles
it is caused by ___ |
encephalitis
autoimmune reaction |
