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24 Cards in this Set
- Front
- Back
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Ziagen (abacavir)
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Hypersensitivity reaction
NRTI |
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Videx EC (didanosine)
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Pancreatitis
Periph. Neuropathy GI intolerance NRTI |
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Zerit (stavudine)
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Periph. Neuropathy
Pancreatitis, Body fat change (lipoatrophy) NRTI |
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Viread (tenofovir)
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GI Intolerance – flatulence, diarrhea
Renal impairment Decrease BMD NRTI |
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Retrovir (zidovudine)
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N, V
Bone marrow suppression –anemia, neutropenia Hyperpigmentation of nails or skin NRTI |
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Emtriva (emtricitabine)
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H, GI intolerance
Rash Hyperpigmentation of palms and feet NRTI |
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Epivir (lamivudine)
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H, GI intolerance
Rash NRTI |
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NRTI class effects
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lactic acidosis
-hepatic steatosis lipodystrophy/lipoatrophy |
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Rescriptor (Delavirdine)
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Headache
Rash GI intolerance- N/V Depressive moods ↑LFTs NNRTI |
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Sustiva (efavirenz)
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CNS effects- drowsy, dizzy, sleepy, insomnia, vivid dreas, hallucination
Teratogenic Skin rash NNRTI |
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Viramune (nevirapine)
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Skin rash-- ↑in women with cd4 count >250 and men >400
Liver toxicity NNRTI |
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Intelence (etravirine)
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Skin rash
GI effects –N Liver toxicity NNRTI |
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NNRTI class effects
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1st gen- cross-resistance
-Rash (7-14days)—treated with antihistamine or corticosteroids, SJS is rare -Liver Toxicity-- ↑LFTs Viramine>Sustiva>Intelence |
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Isentress (raltegravir)
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↑Serum bilirubin –yellow skin/eyes
↑LFTs ↑ Serum creatine kinase –watch for muscle aches, burning, pain Integrase inhibitor |
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PI class effects
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GI, hyperlipidemia, ↑ blood glucose, lipodystrophy, Liver tox, ↑ bleeding
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Prezista (darunavir)
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Caution: sulfonamide allergy
PI |
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Lexiva (fosamprenavir)
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Caution: sulfonamide allergy
PI |
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Aptivus (tipranavir)
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Caution: sulfonamide allergy
Intracranial hemorrhage PI |
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Reyataz (atazanavir)
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Nephrolithiasis
Hyperbilrubinemia PI |
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Crixivan (indinavir)
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Nephrolithiasis
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Viracept (nelfinavir)
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Diarrhea
PI |
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Norvir (ritonavir)
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Diarrhea
Perioral paresthesias PI |
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Invirase (saquinavir)
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nada?
PI |
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Maraviroc (Selzentry)
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cough, fever, liver toxicity
CCR5 entry inhibitor |
