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32 Cards in this Set
- Front
- Back
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what's v-onc role in replication?
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none!
not connected!! |
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T/F retroviruses are usually replication defective
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true.
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which of the 3 types of retroviruses you know (alpha, gamma, lenti) is v-onc negative?
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lentivirus!
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what are FIV, SIV, BIV, VISNA, EIAV and CAEV?
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lentiviruses!
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what are the physical characteristics of the retroviral genome?
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diploid.
inverted dimer linked at 5' ends by a host derived tRNA |
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tell me what the following retroviral genes do:
gag pro pol env LTR |
gag = capsid (not really part of genome..)
pro = replication pol = RNP part for copying env = envelope LTR = promoter, enhancer |
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which type of retrovirus is only transmitted vertically and not both ways?
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endogenous!
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where are the retroviral progeny assembled?
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plasma membrane
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T/F v-onc(-) cannot transform
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false. it just takes way longer.
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which subfamily of pox is of vertebrates?
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chordopoxvirinae
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which virus has a complex virion that doesn't really conform to either icosahedral or rotational?
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Pox
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T/F you need a functional nucleus for pox to replicate
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false!
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what's the PRIMARY mode of transmission for asfar?
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respiratory
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what's the biological vector for asfar (type of tick)?
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SOFT ornithodoros
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where is the primary replication for asfarvirus?
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local lymphoid tissue like tonsils
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what can happen as far as the immune response goes with chronic asfarvirus?
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hypergammaglobulinemia
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how is ASF like hog cholera?
differences? |
both are severe hemorrhage and infection within the vascular system.
hog cholera has focal ulcers whereas ASF has severe pulmonary and pericardial edema. |
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where do the progeny accumulate in herpes?
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the ER space
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how do herpes leave the cell (enveloped mind you)
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exocytosis OR LYSIS!!!!
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T/F syncytia is considered non-productive in herpes
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false. productive
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so once and for all, give the disease type for alpha, beta, and gamma herpes.
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alpha = pneumo/neuro (epithelium)
beta = respiratory (adults), systemic (neonate) gamma = lymphoproliferative |
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where does betaherpes like to go latent?
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in secretory epithelium like mammary glands and salivary glands
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what's the shedding pattern for all 3 herpes?
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alpha = intermittent!!!
beta/gamma - continuous |
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which virus uses temporal AND regional transcription ie those 4 different time periods? this is also the viruria virus.
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adenovirus.
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where is the primary replication for adenovirus?
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site of entry ie pharynx, conjunctiva, or SI
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what 2 systems does adenovirus like?
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RESPIRATORY and ENTERIC
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how does parvo elicit transcriptional control ie 2 genes to 3 mRNAs
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reading frame shift
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what's different about kittens and parvo?
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they get cerebellar infection too
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what virus first replicates in pharyngeal lymphoid tissue?
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parvo.
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T/F parvo can come from semen and milk
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FALSE semen only NOT milk.
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T/F pox can be either enveloped or not
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true.
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T/F getting pox from a skin abrasion will usually go systemic
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false. localized.
remember respiratory goes systemic |
