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20 Cards in this Set

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  • Back
What are the three types of equine encephalitis virus?
western - dead end in horses
eastern - dead end in horses
venezuelan - horses transmit back to mosquito
What is the natural transmission of equine encephalitis virus?
viruses circulate in nature between mosquitoes and wild animals

reservoir hosts
-become infected and develop high enough viral titers in blood to infect mosquitoes
-WEE and EEE are the natural reservoir in birds
-VEE rodents are the enzootic reservoir and horses are the epizootic reservoir
What are Epizootic Cycles (Spillover)
Epizootics begin in nature (increased transmission of virus between mosquitoes and bird and spills over to incidental hosts

incidental host (outside t (cannot infect the natural cycle) are usually dead end = can not infect mosquitos
-except VEE
What is EEE?
Enzootic reservoir cycle between wild birds and mosquitos

many incidental hosts

equine causes appear about 2 weeks before humans

causes GI dz and hepatitis in swine

causes fever, anorexia, lethargy

riskfactor for humans: outdoor activities in an area with EEE infected mosquitoes
What is the incubation period of EEE in humans?
3-10 days
90% people asymptomatic
milkd flu like symptimes
50-90% of survivors will have mild to severe permanent neurological damage

the vector Culex tarsalis are a bridge vector to infect other species

no treatment
What are the Clinical signs of WEE
Equine cases are rarely reported
-begin with fever, lack of appetite and lethargy
-progresses with excitability and then drowsiness

Human cases

estimated that 1:1000 infectious in adults are symptomatic (more serious in children)
-symptoms range from mild flue like illness to encephalitis, coma death
-milk to severe neurologic deficits are seen in survivors
How do you prevent EEE and WEE?
mosquito control
preventing bites
vaccinate horses
What is the veterinary risk for EEE and WEE?
in symptomatic horses with low titers risk is low except during necropsy
How is VEE transmitted?
***FOREIGN TO THE US***
enzootic transmission is between rodents and mosquitoes

epizootic transmission is associated with equines highly pathogenic strains and different mosquitoes
What are the clinical signs of VEE?
Equids
febrile or encephalitis disease

humans 100% symptomatic with neurological symptom in 1%
How do you prevent EEE?
report if in USA

in endemic areas use control methods

sentinel surveillance
Which virus has an equine reservoir?
VEE
What is the immunity from vaccines?
longlasting with natural infection

immunity from vaccines recommend annual booster
What is West Nile Virus?
Flavivirus

maintained in a mosquito-bird-mosquito cycle

birds have 1-4 day viremia post exposure
How is West Nile Virus transmitted?
primarily spread through the bite of in infected mosquito

secondary transmission through bloodborne infectious, lab exposure and life immunity
What are the signs of west nile virus?
in horses:

neurologic: ataxia, hypermetria, weakness, tetraparesis, recumbency, death

Humans:
80% asymptomatic
20 mild febrile illness
What are Hantaviruses?
Bunyavirus that rodents are the reservoir

rodents are asymptomatic and shed for weeks to months (saliva, urine, feces)
How is Hantavirus transmitted?
primarily aerosol

secondary by bite
What are the clinical signs in humans for huntavirus?
severity always depends upon species of virus

-hantavirus pulmonary syndrome
see fever, chills, maylgia,headage increased vascular permeability in the lungs
Fatal in up to 40$ of human cases
-Hemorrhagic Fever with Renal Syndrome
the old world disease
petechial hemorrage, renal damage and cardiovascular shock
What are the risk factors for hantavirus?
human: rodent contact

people who work with rodents or rodent habitats

prevent by reducing human exposure