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31 Cards in this Set

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  • Back
What types of viruses are able to cause viral meningoencephalitis?
Enteroviruses
Coxcackie (A, B)
ECHO
Polio
Who is the most common host for viral meningoencephalitis ?
Healthy kids
Where do enteroviruses normally multiply?
Peyers patches inside the gut
How do viruses from the gut normally spread to the brain?
Hematogenously
What are the specific symptoms/signs of viral meningoencephalitis?
Symptoms:
Headache
Neck pain (+/-)
Photophobia (+/-)

Signs:
Nuchal rigidity
Lethargy
Photophobia
What should always be performed on someone who is suspected of having viral meningoencephalitis?
Lumbar puncture
What are the findings on lumbar puncuture that will differentiate viral meningoencephalitis from bacterial?
Normal CSF Opening pressure
Slightly elevated WBC (as opposed to very high)
Normal glucose (as opposed to low)
What test is most useful for the diagnosis of viral meningoencephalitis?
PCR
What is the treatment for viral meningoencephalitis?
Supportive
What is the best way to prevent viral meningoencephalitis?
Washing hands
What are some systemic illnesses caused by arboviruses?
Yellow Fever
Dengue fever
What are some viruses that cause viral meningoencephalitis?
Eastern Equine
Western equine
St. Louis
LaCrosse
West Nile
Japanese B
What are some arboviruses common to MichigaN?
EEE
WNV
What is a reservoir for arboviruses?
Corvids (crows, jays)
What is the vector for arboviruses?
Mosquitos
What is an uncommon mechanism of transfer for an arbovirus?
Placenta (blood..)
Milk
What are specific sins for viral meningoencephalitis originating from an arbovirus?
Headache
Confusion
Personality changes
Seizures
Stuporous
Comatoase
What is a specific symptom to West Nile Virus?
Paralysis via destruction of the anterior motor horn
What is the most important diagnostic test for arbovirus viral meningoencephalitis?
Serology; Abs against the virus in the serum
What are the properties of the herpes virus?
dsDNA
enveloped
Where is a place that the herpes virus is localized to?
The temporal lobe! (smell)

Very diagnostic!!!!
What is the treatment for viral meningoencephalitis caused by herpes?
Acyclovir IV?
What are findings in the CSF diagnostic of herpes viral meningoencephalitis?
Red blood cells
High lymphocytes
What are the properties of the rabies virus?
Single-stranded
Bullet shapted
Multiplies in the cytoplasm
What is the time course of rabies?
Months for the most severe symptoms
What is the course inside the body of rabie?
Travels along the axon to the CNS.

From CNS goes to the autonomics.
What animals is rabies most associated with in the US?
Bats
Skunks
Coons
Foxes
What animals is rabies most associated with worldwide?
Feral dogs
What are specific signs of rabies?
Frank seizures
Obtunded
Foaming/drooling at the mouth
Refusal to drink a glass of water
What is diagnostic of herpes?
PCR from the neck
Negri bodies on a brain biopsy
What is the mechanism of prevention of rabies?
Vaccine