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31 Cards in this Set
- Front
- Back
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What types of viruses are able to cause viral meningoencephalitis?
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Enteroviruses
Coxcackie (A, B) ECHO Polio |
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Who is the most common host for viral meningoencephalitis ?
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Healthy kids
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Where do enteroviruses normally multiply?
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Peyers patches inside the gut
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How do viruses from the gut normally spread to the brain?
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Hematogenously
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What are the specific symptoms/signs of viral meningoencephalitis?
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Symptoms:
Headache Neck pain (+/-) Photophobia (+/-) Signs: Nuchal rigidity Lethargy Photophobia |
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What should always be performed on someone who is suspected of having viral meningoencephalitis?
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Lumbar puncture
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What are the findings on lumbar puncuture that will differentiate viral meningoencephalitis from bacterial?
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Normal CSF Opening pressure
Slightly elevated WBC (as opposed to very high) Normal glucose (as opposed to low) |
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What test is most useful for the diagnosis of viral meningoencephalitis?
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PCR
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What is the treatment for viral meningoencephalitis?
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Supportive
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What is the best way to prevent viral meningoencephalitis?
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Washing hands
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What are some systemic illnesses caused by arboviruses?
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Yellow Fever
Dengue fever |
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What are some viruses that cause viral meningoencephalitis?
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Eastern Equine
Western equine St. Louis LaCrosse West Nile Japanese B |
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What are some arboviruses common to MichigaN?
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EEE
WNV |
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What is a reservoir for arboviruses?
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Corvids (crows, jays)
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What is the vector for arboviruses?
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Mosquitos
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What is an uncommon mechanism of transfer for an arbovirus?
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Placenta (blood..)
Milk |
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What are specific sins for viral meningoencephalitis originating from an arbovirus?
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Headache
Confusion Personality changes Seizures Stuporous Comatoase |
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What is a specific symptom to West Nile Virus?
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Paralysis via destruction of the anterior motor horn
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What is the most important diagnostic test for arbovirus viral meningoencephalitis?
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Serology; Abs against the virus in the serum
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What are the properties of the herpes virus?
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dsDNA
enveloped |
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Where is a place that the herpes virus is localized to?
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The temporal lobe! (smell)
Very diagnostic!!!! |
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What is the treatment for viral meningoencephalitis caused by herpes?
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Acyclovir IV?
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What are findings in the CSF diagnostic of herpes viral meningoencephalitis?
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Red blood cells
High lymphocytes |
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What are the properties of the rabies virus?
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Single-stranded
Bullet shapted Multiplies in the cytoplasm |
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What is the time course of rabies?
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Months for the most severe symptoms
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What is the course inside the body of rabie?
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Travels along the axon to the CNS.
From CNS goes to the autonomics. |
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What animals is rabies most associated with in the US?
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Bats
Skunks Coons Foxes |
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What animals is rabies most associated with worldwide?
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Feral dogs
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What are specific signs of rabies?
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Frank seizures
Obtunded Foaming/drooling at the mouth Refusal to drink a glass of water |
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What is diagnostic of herpes?
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PCR from the neck
Negri bodies on a brain biopsy |
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What is the mechanism of prevention of rabies?
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Vaccine
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