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4 Cards in this Set
- Front
- Back
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What is viral neutralization? |
When a virus undergoes a loss of infectivity due to antibodies |
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What are some of the mechanisms by which a virus can be neutralised? |
1. Aggregating viral particles together 2. Inhibiting the attachment of viruses to cell receptors 3. Inhibiting viral uncoating and fusion |
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What is the mechanism of action of non-neutralizing antibodies? |
They will bind to a virus but not kill the virus. If the virus has no cell receptor for a neutralising antibody to bind to, the non-neutralising antibody acts as a surrogate receptor. |
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What can be a major problem with non-neutralising antibodies? |
If there are too many non-neutralizing antibodies attached to a virus, the neutralising antibody can't bind. |
