Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
|
Acyclovir mech
|
Chain term; inhib DNA pol; Block DNA synth – prodrug is P by thymidine kinase
|
|
|
Acyclovir tox
|
renal
|
|
|
Herpes drugs
|
Acyclovir & foscarnet
|
|
|
Alternate viral drug
|
Foscarnet, (zoster infections(
|
|
|
foscarnet mech
|
Inhib Viral DNA pol & HIV rev txnase; no activatn reqrd
|
|
|
Foscarnet uses
|
Herpetic & HIV infec
|
|
|
Foscarnet tox
|
Kidney & hypocalcemia
|
|
|
Anti HIV drug mech & drugs
|
Target reverse txn-ase OR protease inhib
|
|
|
NRTI
|
AZT/Zidovudine
|
|
|
NRTI mech
|
Chain term; pyrimidine nucleoside sim to T; inhib viral pol
|
|
|
Nucleoside=
|
Prodrug
|
|
|
AZT/Zidovudine side effect
|
Bone marrow suppresn
|
|
|
NNRTI
|
Nevirapine
|
|
|
drugs that incr liver nzm
|
Rifampin & nevirapine
|
|
|
Nevirapine mech
|
Synergistic w. NRTI; binds reverse txn-ase too!
|
|
|
Protease inhib mech
|
Ritonavir; inhib HIV aspartate protease
|
|
|
Ritonavir adverse eff
|
Hyperglycem; diabetes; hyperlipid; INHIB other drug metab
|
