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24 Cards in this Set

  • Front
  • Back
Why are Arenaviruses important?
zoonotic (hemorrhagic fever)
from pet rodents
Who is the only Veterinarian to win a Nobel Prize? What for? Which Virus?
Peter Doherty studied killer t-cells recognition of self MHC in virus-infected cells
Arenavirus in mice
Why is Hantavirus important?
global dz
Hantavirus Pulmonary Syndrome in people
Deer Mice are reservoir in Canada
What are the 2 glycoproteins of orthomyxoviruses?
Haemagglutinin
Neuraminidase
T or F:
Haemagglutinin must be cleaved to cause serious dz
True
Where do orthomyxoviruses replicate?
Nucleus and cytoplasm
Orthomyxoviruses:
Point mutations = antigenic ___
reassortment = antigenic_____
drift
shift
How is Equine Influenza Dx?
serology
Radial haemolysis
How does Haemagglutinin cleavage effect virulence?
high cleavage = high virulence =systemic infection
low cleavage = low virulence =local infection
What is the unique feature of Reovirus genome?
double stranded, segmented RNA
What are the Rotaviruses know for?
Diarrhea!
1-8 weeks of age
Villi tip damage
T of F:
Rotavirus vaccines do not need to be serotype-specific.
False
How is Rotavirus Diarrhea Dx?
EM
FAT on fecal smear
What are the DDx for diarrhea in calves?
Rotavirus
Coronavirus
BVD
How can Rotavirus be controlled?
Hardy in enviro, therefore disinfection isn't enough
Vaccinate preg. animals
Colostrum important
What should be given as Tx for Rotavirus diarrhea?
colostrum decreases severity or abolishes dz
What are the clinical features of Blue Tongue Virus
fever
salivation
hemorrhage
cyanotic tongue
Coronary band hyperemia
Dx of Bluetongue
serology
done for regulatory testing
What dz does African Horse Sickness look like?
It is the Bluetongue of horses
What is Epizootic Hemorrhagic Dz?
Bluetongue of Cervids
How are the Orbiviruses spread?
BTV, AHS, EHD
culicoides/midges

(Bluetonge, African Horse Sickness, Epizootic Hemorrhagic Dz)
How does Infectious Bursa Dz virus cause Dz?
Tropism for pre-B celss
aquired B-cell immunodeficincy
suseptible to secondary infections
How can Infectious Bursa Dz be controlled?
hardy environmental contaminant
vaccines suck
Infectious Pancreatic Necrosis is a disease of which species?
Salmonid baby fishes
Highly contageous and lethal