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24 Cards in this Set
- Front
- Back
Why are Arenaviruses important?
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zoonotic (hemorrhagic fever)
from pet rodents |
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Who is the only Veterinarian to win a Nobel Prize? What for? Which Virus?
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Peter Doherty studied killer t-cells recognition of self MHC in virus-infected cells
Arenavirus in mice |
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Why is Hantavirus important?
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global dz
Hantavirus Pulmonary Syndrome in people Deer Mice are reservoir in Canada |
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What are the 2 glycoproteins of orthomyxoviruses?
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Haemagglutinin
Neuraminidase |
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T or F:
Haemagglutinin must be cleaved to cause serious dz |
True
|
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Where do orthomyxoviruses replicate?
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Nucleus and cytoplasm
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Orthomyxoviruses:
Point mutations = antigenic ___ reassortment = antigenic_____ |
drift
shift |
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How is Equine Influenza Dx?
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serology
Radial haemolysis |
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How does Haemagglutinin cleavage effect virulence?
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high cleavage = high virulence =systemic infection
low cleavage = low virulence =local infection |
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What is the unique feature of Reovirus genome?
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double stranded, segmented RNA
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What are the Rotaviruses know for?
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Diarrhea!
1-8 weeks of age Villi tip damage |
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T of F:
Rotavirus vaccines do not need to be serotype-specific. |
False
|
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How is Rotavirus Diarrhea Dx?
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EM
FAT on fecal smear |
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What are the DDx for diarrhea in calves?
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Rotavirus
Coronavirus BVD |
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How can Rotavirus be controlled?
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Hardy in enviro, therefore disinfection isn't enough
Vaccinate preg. animals Colostrum important |
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What should be given as Tx for Rotavirus diarrhea?
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colostrum decreases severity or abolishes dz
|
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What are the clinical features of Blue Tongue Virus
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fever
salivation hemorrhage cyanotic tongue Coronary band hyperemia |
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Dx of Bluetongue
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serology
done for regulatory testing |
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What dz does African Horse Sickness look like?
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It is the Bluetongue of horses
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What is Epizootic Hemorrhagic Dz?
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Bluetongue of Cervids
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How are the Orbiviruses spread?
BTV, AHS, EHD |
culicoides/midges
(Bluetonge, African Horse Sickness, Epizootic Hemorrhagic Dz) |
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How does Infectious Bursa Dz virus cause Dz?
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Tropism for pre-B celss
aquired B-cell immunodeficincy suseptible to secondary infections |
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How can Infectious Bursa Dz be controlled?
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hardy environmental contaminant
vaccines suck |
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Infectious Pancreatic Necrosis is a disease of which species?
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Salmonid baby fishes
Highly contageous and lethal |