Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
38 Cards in this Set
- Front
- Back
|
Normocytic
|
Normal in Size for that Species
Cat cells are smaller than dog cells |
|
|
Normochromic
|
Normal in color (hemoglobin content)
|
|
|
Anisocytosis
|
General Term
Increased variation in size of RBC Evaluate size in RCA so cells are not flattened or squished |
|
|
Macrocytosis
|
Larger than normal RBC
|
|
|
Microcytosis
|
Smaller than normal RBC
|
|
|
Anisochromic
|
General Term
Increased variation in color Assoc with Regenerative Anemia |
|
|
Hypochromic
|
Large Central Pallor
Decreased Hemoglobin Assoc with Anemia such as IDA |
|
|
Hyperchromic
|
Cannot exist
Spherocytes appear Hyperchromic |
|
|
Polychromatic cells (dif-quick)
Reticulocytes (NMB stain) |
Young RBC
Diffusely basophilic - presence of RNA Normally 1% Increased # assoc w/ Regenerative Anemia |
|
|
Poikilocytosis
|
General Term
Increased variation in RBC shape |
|
|
Ovalocytes
Elliptocytes |
RBC
Oval, egg, elongated, cigar shaped Assoc w/ Hereditary Elliptocytosis (normal in camellids) Various Anemias |
|
|
Spherocytes
|
NOT Bi-concave
Spherical Assoc w/ Hemolytic anemia, AIHA, Hereditary spherocytosis, Post-transfusion with mismatched blood |
|
|
Target Cell
Leptocytes |
Peripheral Hgb ring, Pallor, then central Hgb
Membrane defect Assoc w/ Non-regenerative anemia, Chronic liver disease |
|
|
Schistocytes
|
Fragmented RBC
< 1/2 normal volume Serious condition Assoc w/ Severe burns, hemolytic anemia, Disseminated Intravascular Coagulopathy (DIC), Iron-deficiency Anemia (IDA) |
|
|
Spiculated
|
General Term
Scalloped, Spicular, spiny projections |
|
|
Echinocytes
|
Scalloped, round regular projections evenly distributed
Can revert back to normal |
|
|
Crenated
|
Usually tech error
|
|
|
Burr cells
|
Irregularly sized and unevenly spaced spicules
# increases as blood urea increases Assoc w/ Renal disease, Lymphosarcoma, Post exercise (esp horses) Rattlesnake bites |
|
|
Acanthocytes
|
Spiny projections irregularly distributed
Related to/may occur with Schistocytes Assoc w/ Hepatic lipidosis, Liver disease |
|
|
Dacryocyte
|
Tear drop or Pear shaped
|
|
|
Stomatocyte
|
Slit or Mouth shaped central pallor
Not biconcave, bowl shaped Assoc w/ Rare inherited disorder Normal in dolphins |
|
|
Keratocyte
Helmet Cell aka cookie or bite cell |
Small, triangular shape
One or two pointed ends |
|
|
RBC Inclusion Bodies
|
Not normal
Due to hematologic disorders |
|
|
Basophilic Stippling
|
Fine or Coarse dark blue granules
Precipitation of RNA during staining Assoc w/ Abnormal RBC formation in bone marrow, Anemia, Lead poisoning |
|
|
Howell Jolly Bodies
|
Round, densely staining purple granule
Remnants of Nucleus Assoc w/ Splenectomy, Abnormal RBC formation |
|
|
Heinz Bodies
|
Denatured, precipitated Hgb
Assoc w/ Acetaminophen poisoning, Onions, Zinc toxicity, Propylene Glycol, Crude Oil ingestion |
|
|
Distribution Patterns
|
Rouleaux: Assoc w/ Tech error, Multiple Myeloma, Normal in some species (horses)
Agglutination: RBCs are irregularly clumped Affects cell count |
|
|
Erythrocyte Indices
|
Show a specific relationship between Hematocrit, Hemoglobin, and RBC count
MCV=Mean Corpuscular Volume MCH=Mean Corpuscular Hemoglobin MCHC=Mean Corpuscular Hemoglobin Concentration Should correlate with appearance of RBC on Morphology Useful for IDing anemia and verifying RBC morphology |
|
|
Mean Corpuscular Volume (MCV)
|
Measures avg size/volume of RBC: Normocytic, Microcytic, Macrocytic
Unit is Cubic microns or femtoliters (fL) |
|
|
Mean Corpuscular Hemoglobin (MCH)
|
Measures avg weight of Hemoglobin to indicate size and color
Unit is picograms (pg) |
|
|
Mean Corpuscular Hemoglobin Concentration (MCHC)
|
Measures ratio of weight of Hgb to volume of RBC. Indicates color: Normochromic, Hypochromic, Well filled
Unit is g/dL |
|
|
Hematopoiesis
|
Production of Blood Cells
|
|
|
Pluripotent Stem Cell
|
In bone marrow. Cell has potential to become WBC, RBC or Plt
|
|
|
WBC
Immature --> Mature |
Blast->Myeloblast->Promyelocyte->Myelocyte->Metamyelocyte->Band->Mature
|
|
|
RBC
Immature-->Mature |
Rubriblast->Prorubricyte->Rubricyte->Metarubricyte->Polychromatophil->Mature
|
|
|
Right Shift
|
Neuts have more than 5 segments
Too Old |
|
|
Left Shift
|
Neuts are mostly bands
Too young |
|
|
How to Judge cell maturity
|
Cell Size (large->small)
Color of Nucleus Color of Cytoplasm |
