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11 Cards in this Set

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What is a vaccine?
It is a product which immunizes against diseases caused by infectious agents such as bacteria and viruses.
Give me 5 examples of each of the 5 types of vaccines discussed in class.
1) MODIFIED LIVE - Combo DA2PPL and DHPPL but becomes a modified live mixed vaccine when mixed with liquid Lepto vaccine.
2) KILLED- Rabies vaccines
3) POLYVALENT-Lepto
4) SUBUNIT-Felv
5) HETEROLOGOUS-Measles to vaccinate against canine distemper
Advantages and disadvantages of Modified Live Vaccine
Advantages:* Rapid onset of protection
* Longer lasting immunity
* Only need one dose, although we usually give a booster

Disadvantages: *Potential for virulence, especially in immunosupressed animals

*Potential for abortion or fetal abnormalities
*must be handled carefully to maintain vaccines viability
What is an adjuvant and what type of vaccines are these added to?
It is a substance that is added to a killed vaccine to slow the release of the antigen into the body which leads to stimulation of the immune system and a higher immune response to the vaccine. It is ALWAYS added to KILLED vaccines.
Advantages and disadvantages of killed vaccines?
ADVANTAGES: *No possibility for virulence
*less likely to be immunosuppressive
*less likely to cause abortion
*remains stable longer in solution

DISADVANTAGES: * Hypersensitivity reactions, possibly linked to adjuvants
*Not as immunogenic as modified live
*Requires adjuvant
What does DA2PPLCV stand for and what is the schedule for it?
Distemper
Adenovirus 2/or Hepatitis
Parainfluenza
Parvo
Leptospirosis - 4 serovars
Corona virus

SCHEDULE: 1st dose at 6-8 weeks
*Booster at 10-12 weeks
*Adults with unknown history initial shot should be followed by a booster in 2-4 Weeks
*Annual boosters thereafter
When is the rabies vaccine typically given the first time?
16 weeks is the common age
What is included in the kennel cough vaccine and what is its schedule?
It contains Bordetella bronchiseptica
Advenovirus2 or Hepatitis
Parainfluenza

SCHEDULE:
Puppies 1st dose 10-12 weeks
Booster 14-16 Weeks

Adults with unknown history initial injection followed by booster in 2-4 weeks

If given by injection, annual re-vaccination schedule

If given intra-nasally:
Puppies at 10 to 12 weeks with a 6 month re-vaccination schedule

Adults after initial vaccination, then every 6 months thereafter
What does FVRCCP stand for and what is the schedule for this vaccine?
Feline Viral Rhinotracheitis
Calici virus
Chlamydia
Panleukopenia

SCHEDULE: 1st dose at 6-8 weeks
2nd dose at 10-12 weeks
3rd, no earlier than 16 weeks

Adults with unknown history, initial injection followed by a booster in 2-4 weeks
What are some causes of vaccine failure? When does maternal interference end in puppies and kittens?
1) Maternal interference- antibodies received from mother interfere with vaccine and this should decrease sufficiently by 16 weeks
2) Stress- resulting cortisone release may inactivate vaccine
3) Age-very young or vary old
4) Nutritional deficiency
5) Immunusupression
6) Concurrent drug administration-usually steriods cause issues
7) Concurrent disease
8) Vaccine interference due to several vaccines being given at the same time
Where would you administer the following vaccines?
a. Rabvac 1
b. Duramune Max 5 4L
c. Bronchisheild III
d. Felovax PCT
e. Felovax LV-K
a. Rabvac 1: SQ in Right hind leg, distal to hip
b. Duramune 5 4L: SQ Right front distal to mid-scapula
c. Bronchisheild III- intranasally
d. Felovax PCT- SQ right front distal to midscapula
e. Felovax LV-k -SQ Left hind distal to hip