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17 Cards in this Set

  • Front
  • Back

Ventilation

Responsible for refreshing Alveolar gas

Tidal Voume

V(t)


-since this is larger than dead space V(D), most fresh air enters alveoli with used air


-the portion that enters alveoli is termed Alveolar volume V(a)



=V(D) + V(a)

Respiratory frequency

-FR


-Number of breaths we take in one minute

Total ventilation

-V(E)


=V(t) x FR = FR x V(D) + FR V(a)



Ultimately V(E) = V(D) + V(a)

Dead space


(Bohr equation)

F(I) = inspired gas fraction


F(a) = Alveolar gas fraction



V(D)/V(T) = (F(E)-F(A)/F(I)-F(A)) oxygen


V(D)/V(T) = (F(A)-F(E)/F(A)) carbon dioxide

Basal Metabolic rate

-Minimal value for demand of oxygen uptake


=VO2



37 Celsius = 250mL/min


38 Celsius = 275 mL/min


36 Celsius = 225 mL/min

Max O2 rate (VO2)

-Increase by 10 fold during exercise

Respiratory exchange ratio

CO2 output/ O2 uptake



Crabs -1


Fats - .7


protein - .8



-In stead state R lung = RQ tissue

Dalton's law

-P total = P1 + P2 + P3

Calculating partial pressure of respiratory gas with fractional concentration

Px=Fx (P(B)-P(H2O))



-P(H2O) of body = 47


-Fraction of oxygen in air = .21


-Sea level barometric = 760 mmHg (decrease with elevation)

Alveolar PO2

P(A)O2=P(I)O2 - (P(A)CO2/R)

Alveolar PCO2

P(A)CO2 = 863 x VCO2/V(A)



-Alveolar ventilation (V(A))



-As ventilation increases, P(A)CO2 decreases and P(A)O2 increases

Normoventilation

-P(A)CO2 normal


(40mmHg)

Hyperventilation

P(A)CO2 reduced



-aspirin toxicity, high altitude hypoxia, progesterone, anxiety, metabolic acidosis

Hypoventilation

P(A)CO2 increased



-Barbiturate overdose, metabolic alkalosis

Hyperpea

-Increase ventilation without change in PCO2


-Exercise


-Expels CO2 produced


-maintains 40mmHg

Tachypnea

Breathing with increased respiratory frequency