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47 Cards in this Set

  • Front
  • Back

Where is blood direct after passing the CNS capillary beds?

Directed our of the CNS through veins

Where does the cerebral venous system empty?

Through one major pair of vessels - Internal Jugular Veins



What do the cerebral and spinal veins lack and what is this significance?

They lack valves which means the flow through veins can be altered by pathologic processes

What are dural sinuses?

Venous structures formed at the edges of the dural septa that also receive CSF drainage

What the the p rimary sinuses?

Superior sagittal sinus and Transverse sinus




Located at egde of falx cerebri and tentorium cerebelli

Where do all of the sinuses meet?

Confluence of the sinuses

What is the straig sinus?

Formed at the jct of the falx cerebri and Tentorium cerebelli

Where does the straight sinus start?

Jct of inferior sagirral sinus on the inferior margin of the falx cerebri and great cerebral vein

Where does the straight sinus receive blood drom?

Deep Brain structures

What does the dura surround?

Sella turcica and pituitary and forms a ring of dural sinuses

Describe the cavernous sinuses?

Enclose the carotid arteries and parts of cranial nerves 3,4,5, and 6

What connects the cavernous sinuses?

Anterior and Posterior intercavernous

Why is the cavernous sinus subject to adjacent infections?

Due to its location near the nasal sinus




can produce deficits in the cranial nerves within the sinus, affect the pituitary gland or adjacent structures

Describe the transverse sinus

Drains in to the sigmoid sinus that is continuous with the internal jugular vein traveling through the jugular foramen

What is a stroke?

CVA




Sudden focal neurological syndrome resulting from cerebrovascular disease

What are the characteristics of a CVA

Sudden onset of neurological deficits with subsequent recovery of brain function occuring gradually and to a varying degree

What must happen for a CVA to be classified as a stroke?

The event must be accompanied by neurological deficits which last longer than 24hr

What processes canaffecct the cerebral vasculature?

Occlusion of the vessel lumen


Rupture of vessel


Altered permeadbility of vessel wall


Changes in the viscosity or quality of blood that affect blood flow

Non modifiable risk factors for stroke?

Age


Ethnicity


Gender


Family History


Genetics

Modifiable risk factors for stroke?

Arterial Hypertension


TIAs


Prior Stroke


Cardiac Dz


DM


Smoking


EtOH


Oral Contraceptive


Obesity

Describe an Occlusive stroke

Due to closure of a blood vessel


-Embolism, Thrombosis




Most common

Describe Hemorrhagic Stroke

Due to bleeding from a vessel


-Hypertension, aneurysm, AV malformation




May be extraparenchymal or intraparenchymal

Stoke Syndromes: Anterior Circulation

More Common




Anterior cerebral artery


Middle cerebral artery

Stroke Syndromes: Posterior Circulation

Posterior Cerebral artery


Branches to thalamus


Basilar artery


Cerebellar arteries

What does the Anterior Cerebral Artery supply?

Medial aspect of the frontal and parietal lobes


-Branches extend over the border of the hemisphere onto the lateral surface

Deficits due to Anterior Cerebral Artery?

Paracental lobule - movement and sensation of lower limb




Frontal Lobe - Executive functions (decision making and planning) Urinary control




Medial Limbic Area - Motivation attention, physical self mage




Corpus Callosum

Clinical Picture of Anterior Cerebral Artery Stroke?

Sensorimotor


Leg deficits more than arm




Paralysis of the opposite foot and lef - UMN


Sensory deficits over toes, foot, and leg




Transcortical motor aphasia if in dominant hemisphere

Describe the middle cerebral artery

Usuall the larger of the terminal branches




Moves laterally through the sylvian cistern, giving off branches to the basal ganglia and branches to the lateral and rostal aspectsof the temporal loes

What does the middle cerebral artery supply?

Primary sensory and motor areas forface and arm


Left side - speech area


Optic radiation


Parietal association cortex


Frontal eye field

Clinical presentation of MCA stroke

Paralysis of opposite face and arm


Sensory deficits over opposite face and arm


Wernikes area aphasia if on the left side


Right Parietal: inattention and contralateral neglect


Meyers loop - visual field defects


Frontal eye fields - transient paralysis of conjugate gaze to the contralateral side

What else does the MCA supply?

Basal Ganglia and internal capsule. Occlusion can interrupt axons ascending and descending without direct damage to cortex

Describe the posterior circulation

Vertebral, basilar, and posterior cerebral arteries




Supply the brainstem, cerebellum and posterior inferior aspcts of the cerebuum



Where does the posterior cerebral artery run?

On the temporal lobes and runs posteriorly to include the ventral and medial surfaces of the temporal and occipital lobes

What is supplied by the PCA

Primary visual cortex




Parts of the thalamus




Visual cortex- medial occipital


Temporal lobe, caudal parietal lobe and corpus callosum

Clinical Presentation of occlusion to the


Visual cortex- medial occipital


Temporal lobe, caudal parietal lobe and corpus callosum

Homonymous Hemianopia


Pure Alexia - inability to read

Clinical Presentation to occlusion to the thalamus

Sensory deficits with deep territory involvement. Thalamic pain syndrome

What supplies the brainstem?

Branches of the vertebral, basilar and PCA




Short Branches - anterior and medial


Long circumfrential branches - dorsolateral structures

What occurs with occlusion of short branches?

Tends to disrupt major tracts located in the anterior aspect of the brain stem




-Motor pathways


-Medial Lemniscus (DCML)

Result of short branch occlusion

Contralateral hemiparesis and also contralateral decreased vibration, dis. touch, proprioception

Occlusion of the long circumferential branches

Disrupt more dorsal located structures and tracts including...




Spinocerebellar pathways


Anterolateral system


Spinal trigeminal nucleus


Descending sympathetic fibers`

Result of long cercumferential branch occlusion?

Cerebellar associated ipsilateral ataxia




Horner Syndrome




Decreased pain and temp from face




Contralateral loss of pain and temp from body

Describe cranial nerve innvolvement inn relation to the brainstem

CN 3,4 - midbrain




CN 5, 6, 7 - Pons




CN 9, 10, 12 - Medulla

Majot risk factors for Lacunar strokes

Hypertension, diabetes, and atherosclerotic dz

What is MID

Multi Infarct Dementia




Can be brought on by an acculumation of small deficits due to lacunar stokes and confused with Alzheimers dz

Desccribe TIAs the aresult from small emboli from plaques

If in the internal carotid may involve retinal branches of the ophthalmic artery.




My result in transient blindness on affected side

Symptoms of TIA/Transient blindness

Sudden onset of a fog, haze, scum, curtain, shade, blur, cloud, or mist




Sudden, brief 1-5 min painless

What involvement is more common in TIA

Anterior cirulation and presentation is more stereotypical for recurrent carotid TIA