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26 Cards in this Set
- Front
- Back
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Where are vasopressin and oxytocin synthesized
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Magnocellular neuorns of parventtricular and supraoptic hypothalamic nuclei
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Main function of vasopressing
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Upreg aquaporins to cortical collecting duct to increase water reabsorption
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Cause by excess vasopressing
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SIADH
low volume, high concentrated urine |
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Ineffective vasopressin secretion
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Diabetes insipidus
High volume, low concentrated urine |
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V1 vasopressin receptor mediates
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vasoconstriction
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V2 vasopressin receptor mediates
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aquaporins
ACTH stimulation |
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Drug of choice for diabetes insipidus
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Desmopressing acetate
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Vasopressin drugs
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vasopressin
lypressin desmopressin |
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AVP inhibitors
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Demclocycline (TCA)
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AVP enhancing drugs
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Chlorpropamide
Carbamazsepine Clofibrate |
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PGE2
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Dinoprostone
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PGF2 alpha
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Carbeprost
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Use for prostoglandins
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Midtrimester abortions
Evacuate the uterus postpartum hemorrhage |
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SE of prostoglandins
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nausea, vomiting, diarrhea
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Ergonovine
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Ergot alkaloids that causes powerful uterine contractions
to control post partum |
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CI for ergonovine
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Hypertension
to avoid ergotism |
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drug for premature labor
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Ritodrine
Terbutaline Stops contractions |
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SE of ritodrine
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increases renin secretion
edema hyperglycemia |
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Use for oxytocin
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Induce labor
Control post partum bleeding assist with breast feeding |
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Drug of choice for diabetes insipidus
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Desmopressin
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treat SIADH
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demeclocycline
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Causes of nephrogenic diabetes insipidus
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Lithium
Demeclocycline |
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Tx nocturnal enuresis
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Desmopressin
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Tx for bleeding disorders
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von Willebrands factor
hemophilia A desmopressin |
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GI bleeding
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vasopressin
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SE and CI of desmopressin
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coronary vasoconstriction
not for pts with renal failure caution with CHF or HTN |
