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26 Cards in this Set

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  • Back
Where are vasopressin and oxytocin synthesized
Magnocellular neuorns of parventtricular and supraoptic hypothalamic nuclei
Main function of vasopressing
Upreg aquaporins to cortical collecting duct to increase water reabsorption
Cause by excess vasopressing
SIADH

low volume, high concentrated urine
Ineffective vasopressin secretion
Diabetes insipidus

High volume, low concentrated urine
V1 vasopressin receptor mediates
vasoconstriction
V2 vasopressin receptor mediates
aquaporins
ACTH stimulation
Drug of choice for diabetes insipidus
Desmopressing acetate
Vasopressin drugs
vasopressin
lypressin
desmopressin
AVP inhibitors
Demclocycline (TCA)
AVP enhancing drugs
Chlorpropamide
Carbamazsepine
Clofibrate
PGE2
Dinoprostone
PGF2 alpha
Carbeprost
Use for prostoglandins
Midtrimester abortions
Evacuate the uterus
postpartum hemorrhage
SE of prostoglandins
nausea, vomiting, diarrhea
Ergonovine
Ergot alkaloids that causes powerful uterine contractions

to control post partum
CI for ergonovine
Hypertension

to avoid ergotism
drug for premature labor
Ritodrine
Terbutaline

Stops contractions
SE of ritodrine
increases renin secretion
edema
hyperglycemia
Use for oxytocin
Induce labor
Control post partum bleeding
assist with breast feeding
Drug of choice for diabetes insipidus
Desmopressin
treat SIADH
demeclocycline
Causes of nephrogenic diabetes insipidus
Lithium

Demeclocycline
Tx nocturnal enuresis
Desmopressin
Tx for bleeding disorders
von Willebrands factor
hemophilia A

desmopressin
GI bleeding
vasopressin
SE and CI of desmopressin
coronary vasoconstriction
not for pts with renal failure
caution with CHF or HTN