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11 Cards in this Set

  • Front
  • Back
Wegener's Granulomatosis
Small vessels
c-ANCA
necrotizing vasculitis
granulomas in lung, airways
glomerulonephritis
Tx: cyclophosphamide, steroids
Microscopic Polyangiitis
Small vessels
p-ANCA
necrotizing vasculitis
no granulomas
Pauci-immune
p-ANCA
kidney vasculitis --> crescentic GN
no ABs
Churg-Strauss
Small vessels
p-ANCA
granulomatous with eosinophilia
lung, heart, skin, kidneys, nerves
often w/ allergies
Sturge Weber
Small vessels
congenital
port wine stain, leptomeningeal angiomatosis (cerebral AVM)
HSP
Small vessels
palpable purpura on butt and legs of kids
arthralgia, GI pain/bleeding, after URI
IgA complexes, assc w IgA nephropathy
Buerger's
(thromboangiitis obliterans)
Medium vessels
raynauds, digital amputation in smokers (other parts too)
Kawasaki
Medium vessels
necrotizing vasculitis, thrombosis in kids/asians
coronary aneurysms, congested conjunctiva, strawberry tongue
Polyarteritis nodosa
Medium muscular arteries
necrotizing immune complexes
cutaneous lesions of different ages, all other organs except lungs
assc w HBV
Tx: steroids, cyclophosphamide
Takayasu
Large arteries
pulseless disease, from thickening of aortic arch, great vessels
young asian ladies
fever, arthritis, night sweats, myalgia, skin nodules, eye problems
high ESR
Temporal (giant cell) arteritis
Large arteries
elderly women
granulomatous inflammation
headache, jaw pain, loss of vision
high ESR
systemic involvement in half
Tx: steroids