Vascular Pathology

Front 1

Buerger's Disease Buerger's disease is also known as?

Back 1

smoker's disease, thromboangiitis obliterans

Front 2

Buerger's Disease What are the Sx (5)?

Back 2

intermittent claudication, superficial nodular phlebitis, cold sensitivity, severe pain in affected part, may lead to gangrene

Front 3

Buerger's Disease What is the Tx?

Back 3

Quit smokng

Front 4

Takayasu's arteritits Also known as ?

Back 4

pulseless disease

Front 5

Takayasu's arteritits What is it?

Back 5

thickening of aortic arch and/or proximal great vessels

Front 6

Takayasu's arteritits ESR elevated?

Back 6

yes

Front 7

Takayasu's arteritits Primarily affects whom?

Back 7

Young Asian Females

Front 8

Takayasu's arteritits Mnemomic

Back 8

FAN MY SKIN On Wednesday

Front 9

Takayasu's arteritits Sx (7)

Back 9

Fever, Arthritis, Night Sweats, Myalgia, Ocular Disturbances, Weak pulses in upper extremities

Front 10

Temporal Arteritis: Also known as?

Back 10

Giant Cell Arteritis

Front 11

Temporal Arteritis: Affects what vessels?

Back 11

medium and small arteries (usually carotid branches)

Front 12

Temporal Arteritis: ESR elevated?

Back 12

yes

Front 13

Temporal Arteritis: Primarily affects whom?

Back 13

Elderly Females

Front 14

Temporal Arteritis: Sx (3)

Back 14

Unilateral Headache

Front 15

Temporal Arteritis: Many patients are also affected with this syndrome

Back 15

Polymalgia Rheumatica

Front 16

Temporal Arteritis: Tx (?)

Back 16

Steroids

Front 17

Polyarteritis Nodosa: How would you describe the inflammation in this disease?

Back 17

necrotizing, caused by immune complex deposition

Front 18

Polyarteritis Nodosa: In which vessels?

Back 18

small to medium-sized muscular arteries, renal and visceral vessels

Front 19

Polyarteritis Nodosa: ESR elevated?

Back 19

yes

Front 20

Polyarteritis Nodosa: Sx (7) … and they are SO specific

Back 20

fever, weight loss, malaise, abdominal pain, headache, myalgia, hypertension

Front 21

Polyarteritis Nodosa: Other findings

Back 21

cotton-wool spots, microaneurysms, pericarditis, myocarditis, palpable purpura

Front 22

Polyarteritis Nodosa: What viral infection is found in 30% of PN patients?

Back 22

Hepatitis B

Front 23

Polyarteritis Nodosa: what antibody is associated with this disease?

Back 23

P-ANCA

Front 24

Polyarteritis Nodosa: What two ways can you remember that?

Back 24

P-ANCA --> PAN (PolyArteritis Nodosa), Just memorize it

Front 25

Polyarteritis Nodosa: What does P-ANCA refer to?

Back 25

Perinuclear pattern of Antineutrophil Cytoplasmic Antibodies

Front 26

Polyarteritis Nodosa: Primarily affects whom?

Back 26

Young males

Front 27

Polyarteritis Nodosa: Tx

Back 27

Corticosteroids, Azathioprine, Cyclophosphamide

Front 28

Wegener's Granulomatosis What are three major findings (hint: they are necrotizing)

Back 28

Focal Necrotizing Vasculitism, Necrotizing granulomas of the lung and upper airway, Necrotizing glomerulonephritis

Front 29

Wegener's Granulomatosis Sx (7)

Back 29

Perforated nasal septum, Chronic Sinusitis, Otitis Media, Mastoiditis, Cough, Dyspnea, Hemoptysis

Front 30

Wegener's Granulomatosis What antibody is associated with this disease

Back 30

C-ANCA

Front 31

Wegener's Granulomatosis What should you look for on CXR?

Back 31

large nodular densities

Front 32

Wegener's Granulomatosis Tx

Back 32

Corticosteroids, Azathioprine, Methotrexate

Front 33

Kawasaki Disease: Who gets it?

Back 33

infants, kids

Front 34

Kawasaki Disease: What is the disease course?

Back 34

acute, self-limiting

Front 35

Kawasaki Disease: What vessels are involved?

Back 35

small and medium sized

Front 36

Kawasaki Disease: What does CRASH stand for

Back 36

Conjunctivitis, Rash (truncal), Aneurysms of Coronary Arteries, Strawberry tongue, changes in lips/oral mucosa; Hands and Feet show induration and desquamation