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68 Cards in this Set

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60 yo F with single episode of woekaness and numbness lasting for 15 minutes.
1. Diagnosis?
2. Workup?
3. Risk of recurrence?
4. Treatment options?
1. TIA
2. Neuro exam, carotid exam/duplex, murmurs --> (if yes, echo)
3. up to 40%
4. medical: aspirin; surgical: carotid endarterectomy
1. What two groups is carotid endarterectomy indicated?
2. What study supports one of these indications?
1. symptomatic AND >70% stenosis, asympomatic bruit and >70% stenosis
2. NASCET trial showed best stroke prevention (as compared to aspirin and no treatment) - NNT of 6 to prevent stroke in two years in symptomatic patients with carotid stenosis 70-99%
1. 2-year risk of stroke with symptomatic carotid artery stenosis - no treatment, aspirin and carotid endarterectomy?
2. What about 5-year risk of stroke asympomatic CAS > 60% - CEA versus aspirin?
2. where do these results come from respectively
1. no treatment: 40%, aspirin: ~26%, CEA: ~9%
2. CEA: 5% verus aspirin: 11%
2. NASCET AND ACAS trial respectively
perioperative risk of stroke of carotid endarterectomy?what other risk of surgery is important to discuss with patient?
1-3%
nerve injuries (hypoglossal, vagus, branch of facial nerve)
what are two important elements of carotid endarterectomy surgery?
1. assessment of neurologic status: (talking to patient if awake, EEG - general anesthesia)
2. good BP control
think about perioperative risks
What is amaurosis fugax? Hollenhorst plaque?
transient blindness form an emboli traveling from ICA to opthalmic artery; Hollenhorst plaque- cholesterol embolus seen as bright shiny spot in retinal artery after episode
eyes
aphasia with TIA in carotid dz, which side carotid affected?
left carotid
Is carotid endarterectomy indicated with prior stroke?
depends, if duplex show stenosis, a and neuro fnxn is good, then yes
65 yo m hx of acute pain onset in leg with difficulty moving it; PE: absence of pulses in legs, cool and cyanotic, dereased sensation, weakness - Diagnosis? Management?
1. Diagnosis: acute arterial embolus
2. first, heparin ---> then to OR for revascularization via balloon catheter embolectomy
Time for revascularization after an arterial embolus directly impacts recovery. After how long is after ischemia starts is there a high likelihood of impaired limb or even amputation?
6 hours
6 p's of arterial occlusion?
pain (ischemic rest pain), pulselessness, pallor, poikolothermia (cold below site of occlusion), parasthesias, paralysis
procedure of choice for revascularization after acute arterial embolic event (e.g. femoral artery)? Typically done intraoperatively to assess revascularization?
balloon catheter (Fogarty) embolectomy; intraoperative arteriogram (intra-arterial thrombolyitc therapy used if residual thrombus)
what can occur after revascularization procedure in extremity? Why?
compartment syndrome (due to edema causes by reperfusion edema --> increased pressure --> irreversible muscle/nerve injury)
1. most common sources/causes of arterial emboli (3)?
2. most common sites?
1.a. fib, MI, atherosclerotic plaque
2. femoral>iliac>popliteal>carotid&aortic saddle
diagnosis and treatment for compartment syndrome?
1. needle with pressure-measuring device
2. fasciotomy
long term management post-embolectomy?
1. warfarin chronically
2. echo (aortography/CT) to look for embolic source
exercise-induced calf pain relieved with rest? diagnosis? etiology?
intermittent claudication; atherosclerotic occlusion
1. what are signs/symptoms that may be present in claudication syndrome (5-7)? 2. Coexisting conditions? (name 2)
1. bruits, reduced pulses, thrills, skin ulcerations, motor/sensory loss, shiny skin, dependent rubor
2. DM, CAD
most common site for occlusive dz in LE? what pulses reduced/absent?
superficial femoral artery; popliteal and pedal
two best noninvasive ways to assess peripheral vascular disease?
1. ABI (ankle/brachial) pressures with doppler
2. doppler tracings (to detect stenotic areas)
1. normal ABI
2. mild claudication?
1. >1.0
2. 0.6-0.8
4 signs of PVD/insufficiency? give 4 biggies
.1 reproducible exercise-induced ischemia/pain
2. toe and foot nonhealing ulcerations
3. gangrene
4. rest pain (forefoot)
normal doppler waveform form? what happens in less compliant vessel due to atherosclerosis?
triphasic; biphasic (moderate stenosis), monophasic (severe stenosis)
*loses reverse flow
give percentages of patients that: a)require vascularization, b)require subsequent amputation, or c)remain stable or improve
stable or improve (70%), vasc (20%), amp (10-15%)
;Nonoprative therapy for claudication syndrome (3-4)? 1st one most important
exercise, lifestyle modifications (smoking cessation, weight loss, dietary changes), lipid-lowering agents
Does workup for claudication syndrome include an arteriogram?
No, it has inherent risk - only done preoperatively
60 yo woman with claudication syndrome with absent femoral pulse? diagnosis? treatment options (3)?
aortoiliac occlusive disease; balloon dilation, stent placement, surgical revascularization
clinical measure that would suggest need for revascularization with nonhealing ulcer in diabetic?
ABI<0.3
Or systolic BP in ankle <80
procedure used for occlusion of SFA?
Fem-pop (saphenous vein graft)
high grade stenosis of iliac artery?
large diameter aorto-fem graft, OR stent/balloon dilation
high grade stenosis of iliac artery and occlusion of SFA? procedure?
aortoiliac reconstruction, fem-pop and distal revscularization
occlusion of SFA and popliteal arteries?
Fem-pop bypass (with distal connection to distal anterior/posterior tibial arteries)
multiple obstructionsin upper and distal leg, with run off vessels below ankle?
amputation indicated
post-reconstruction/revascularization imagine, plus long term management (2-3)?
most common condition causing death?
1. duplex exams of graft,
2. aspirin,
3. lipid control,
4. foot care education
CAD (peripheral is marker)
factors going into whether to reconstruct aortoiliac occlusive disease (3)? procedure?
1. presence of rest pain
2. level of discomfort
3. operative risk
Procedure: graft from aorta @ renal vein to aortoiliac branch / common iliacs
risks of aortobifemoral bypass due to clamping/unclamping aorta?
clamping: inc cardiac work (MI)
unclamping aorta: bleeding, hypotension
post-op complication of revascularization procedure in which painful, cyanotic big toe?
atheroembolization - blocking small pedal/digital arteries
Called Trash Foot
discharge instructions/meds post-aortobifemoral / aortoiliac graft revascularization?
1. call if signs of infection (risk of graft infection)
2. start aspirin
3. antibiotics
what is chance of cardiac event (e.g. MI, arrhythmia, heart failure) in major revascularization procedure?
10% (mortality of approx 2-3%)
indications for coronary angiography prior to major vascular surgery (3)?
mod-severe angina, HF with exertion, LVEF<20%
indications for thallium (D-T) scan prior to major vascular surgery?
MI hx, moderate angina, mild angina with sedentary lifestyle
problem with D-T thallium scan?
Low positive predictive value, resulting high rate of coronary angiography
physical exam of pulsatile mass in abdomen - next steps?
abdominal U/S or CT to determine level of aorta and size
what are two big risk factors for AAA?
1. male
2. + family hx of AAA (11x risk)
AAA associated with what other aneurysms?
iliofemoral and popliteal aneurysms
elective repair of AAAs > __ cm assuming what two conditions?
>5cm; will tolerate surgery and life expectancy > 2 years
in AAA repair, what is done?
prosthetic graft inserted is sewn to prozimal and distal ends of aneurysm;
note: aneurysm not resected
concern with AAA postoperatively? management?
third space losses; aggressive resuscitation for 1-2 days until mobilization of fluid, then possibly fluid restriction / diuretics
possible postoperative complication in men of AAA repair?
impotence from disturbance of hypogastric circ (from over aortic bifurcation)
68 yo male, pale, BP 102/60, passed out in AM, abdominal pain, weakness, tenderness in epigastrium and back pain. what do you feel for on clinical exam? diagnosis and management?
feel for pulsatile abdominal mass; ruptured AAA; management: straight to OR
what active resuscitation for AAA is performed in OR?
None - volume expansion can worsen contained rupture into free intraperitoneal resuscitation
major perioperative risk and %mortality in rupture AAA repair?
exsanguination (bleeding out); up to 80% mortality
small amt of bloody diarrhea 3 days post-op AAA repair - what ssuspected? What about upper GI bleed one year post-AAA repair?
1. ischemic colitis (usually involving rectosigmoid segment)
2. aortoenteric fistula
1. initial steps in management of ischemic bowel dz? name 4-5
2. surgical treatment?
1. bowel rest / NPO, antibiotics, IV fluids, maintenence of hematocrit, NGT (or other decompression)
2. surgical (resection of nonviable bowel)
3 year post-op AAA tepair,patient found to have graft infection by CT scan - what therapy indicated?
removal of graft, debridement of infeted tissue, revascularization by extra-anatomic bypass,and long term abc
three major complications of AAA repair (with graft), occuring days to years after?
1. ischemic colitis
2. graft infection
3. aortoentric fistula
49 yo woman with 6 mo hx of post-prandial pain, 20 lb weight loss, intermittent diarrhea, and multiple abdominal bruits - what suspected? cause? treatment?
1. chronic mesenteric ischemia
2. atherosclerotic occlusion to celiac and SMA
3. revascularization via prosthetic/saphenous vn from aorta to affected vessel
58 yo male comes to ED with sudden onset of chest pain and back pain - BP is 200/140. with HR of 120. diagnosis? '
aortic dissection
management of aortic dissection? exception?
control HTN with Beta-blockers; dissection of ascending aorta needs to be repaired surgucally
67 yo woman post-op day 2 with suspected DVT - what is most reliable clinical sign. Also, name couple others that aren't so specific
1. New onset, unilateral leg swelling
2. Homan's sign, calf pain
confirmation of diagnosis of DVT via what?
venous duplex ultrasound
49 yo F present with 6 month hx of postprandial abdominal pain with postprandial pain with a 20lb weight loss, and intermittent diarrhea. multiple abdominal bruits
1. suspected diagnosis?
2. evaluation and potential treatment?
1. chronic mesenteric ischemia
2. mesenteric arteriogram, and potential revascularization (bypass)
67 yo F post-op for colecotomy develops mild LE swelling. Duplex US of LE reveals a DVT with extension into proximal thigh.
1. Treatment?
2. Monitoring of patient's treatment for efficacy? what is therapeutic?
3. What else should be monitored?
4. Bridging to coumadin why?
1. IV heparin (standard of LMWH)
2. PTT 1.5-2x normal
3. platelet count for risk of thrombocytopenia
4. prothrombotic state initially with warfarin b/c of deficiency of protein C (hypercoagulable state), coumadin allows long term anticoagulation
Long term therapy post-DVT post-op?
Warfarin can be started before discharge with target INR of 2-3.
10% of patient with DVT develop what complication marked by chronic, marked edema with skin ulceration around ankle areas? best treatment?
postthrombotic state (chronic venous insufficiency)
Best treatment: compression stockings / support hose
DVT follows 20% of general surgeries and up to 70% of orthopedic LE procedures - what are prophylocatic measure that can be taken post-op (6 answers)? Which two have solid demonstrated efficacy?
1. leg elevation
2. compression stocking
3. venodynes / SCDs
4. early post-op ambulating
5. low dose heparin (LDH)
-SCDs and LDH
how (meaning how much and how often) do you administer pre and post-op heparin for DVT prophylaxis?
5000 units x 1 preoperatively, q8-12 post-op
50 year old post-op day 4 for SBO reports brief episode of acute SOB overnight? No hx of cardiopulmonary disease (asthma, COPD, MI, etc.)
1. Highest on differential?
2. What is broad workup for significant SOB in post-op patient (not necessarily in this patient) (3-4 things)?
3. what about in this case, what test for suspected diagnosis (2)?
1. PE
2. pulse ox, CXR, EKG, ABG
3. CTPA (CT-pulmonary angiogram), V-Q scan