Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
Patient older than 50
LARGE VESSEL (aorta/major artieries) granulomatous arteritis Assc. with polymyalgia rheumatica Typically the temporal artery transmural inflammation with lymphocytes and giant cells Disruption of the elastic lamina |
Giant Cell Arteritis
|
|
|
Patient younger than 50
LARGE VESSEL (aorta/major artieries) granulomatous arteritis transmural inflammation with lymphocytes and giant cells Disruption of the elastic lamina |
Takayasu Arteritis
|
|
|
Medium vessel necrotizing vasculitis WITHOUT glomerulonephritis or vasculitis in arterioles, capillaries, or venules
Segmental necrotizing inflammation with conspicuous poly and monocyte infiltrates. Fibrin present. Endpoint=sclerosis (>1 week) |
Polyarteritis Nodosa
|
|
|
Child with mucocutaneous lymph node syndrome and vasculitis (strawberry tongue and cervical lyphadenopathy)
Medium vessel necrotizing vasculitis WITHOUT glomerulonephritis or vasculitis in arterioles, capillaries, or venules Segmental necrotizing inflammation with conspicuous poly and monocyte infiltrates. Fibrin present. Endpoint=sclerosis (>1 week) |
Kawasaki disease
|
|
|
Young patient with purpura, nephritis, and abdominal pain.
Small vessel vasculitis (necrotizing polyangitis) that involves the capillaries- glomerulonephritis and lung, venules, and some arteries IF: granular deposits- IgA |
Immune complex vasculitis:
Type: 1. Henoch-Schonlein purpura (abdominal pain,nephritis,purpura), IgA deposits |
|
|
Young patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias
Small vessel vasculitis (necrotizing polyangitis) that involves the capillaries- glomerulonephritis and lung, venules, and some arteries IF: granular deposits-cryoglobulin immune deposits |
Immune complex vasculitis:
Cryoglobunlinemic vasculitis |
|
|
Patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias
Small vessel vasculitis (necrotizing polyangitis) that involves the capillaries- glomerulonephritis and lung, venules, and some arteries IF: linear glomerular staining |
Anti-GBM antibodies/
Goodpasture's syndrome |
|
|
Older patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias.
Patient also has asthma and eosinophilia Small vessel vasculitis (necrotizing polyangitis) that involves the capillaries- glomerulonephritis and lung, venules, and some arteries IF: little/no immunoglobulin staining cANCA positive (mostly) |
Pauci-immune (ANCA) disease
Type: Churg-Strauss Syndrome |
|
|
Older patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias
Typically glomerulonephritis and respiratory tract affected Patient also has granulomatous inflammation Small vessel vasculitis Patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias Small vessel vasculitis (necrotizing polyangitis) that involves the capillaries- glomerulonephritis and lung, venules, and some arteries IF: little/no immunoglobulin staining pANCA postive (mostly) |
Pauci-immune (ANCA) disease
Type: Wegner's granulomatosis (or ANCA granulomatousis) |
|
|
Older patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias
Typically glomerulonephritis and respiratory tract affected Small vessel vasculitis Patient with palpable purpura in the extremities, renal and other findings like artitis/arthraligias Small vessel vasculitis (necrotizing polyangitis) that involves the capillaries- glomerulonephritis and lung, venules, and some arteries NO granulomatous inflammation seen on Bx IF: little/no immunoglobulin staining pANCA postive (mostly) Most common cause of pulmonary-renal syndrome |
Pauci-immune, ANCA vasculitis
Type: Microscopic poliangiitis |
