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15 Cards in this Set
- Front
- Back
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Vanco
Mechanism |
Binds D-ala-D-ala
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Vanco
Bacteriocidal or static? |
Cidal
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CA-MRSA
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Resistant to beta-lactams
Clindamycin |
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HA-MRSA
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High level beta-lactam resistance
Vanco |
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VISA
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Intermediate vanco resistance
Overproduction of PBP2a Thicker cell wall that can't be penetrated |
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VRSA
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van A resistance
Transposon from enterococcus faecium |
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vanH
vanA vanX |
Make lactate
Resistance Removes terminal alanine |
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Vanco
Absorption Distribution Metabolism Excretion |
IV
Poor CSF unless meninges inflames Little metabolism Glomerular excretion |
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Vanco
Therapeutic use |
HA-MRSA
C dif. |
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Red man syndrome
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Flushing
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Dapto
Mechanism |
Binds bacterial membrane in a Ca dependent manner. This causes a deopolarization of the membrane
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Dapto
Resistance |
Alteration in phospholipids of membrane
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Dapto
Absorption Distribution Metabolism Excretion |
IV
No CSF Little metabolism Renal excretion |
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Dapto
Clinical uses |
VISA and VRSA
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Dapto
Adverse effects |
Elevation in creatine phosphokinase
Muscle injury |
