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13 Cards in this Set
- Front
- Back
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What is the purpose of vaccination?
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to produce immunity to an infectious agent
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What are the two ways to gain immunity to an infectious disease?
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passive immunization
active immunization |
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What are examples of passive immunization?
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administration of antibodies already produced
transfer via colostrum |
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What are the drawbacks of passive immunization?
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short duration
may get anaphylaxis doesn't stimulate the animal's own immune responses |
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What are the drawbacks of active immunization?
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not immediately affective
may require boosters |
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What two types of studies are most typically used for vaccine efficacy study?
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challenge study
field trial |
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How does a challenge study work?
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purposely expose the animals (control and vaccinated) to the infectious agent, see which ones develop disease
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How does a field trial work?
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vaccinate, allow natural exposure and monitor for disease
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Which type of vaccine efficacy study more easily demonstrates the outcome of interest?
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challenge study
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Which type of vaccine efficacy study is more reflective of "real life" exposures?
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field trial
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What measures can be used to assess vaccine efficacy?
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incidence in each group
risk ratio absolute risk difference attributable fraction number needed to treat |
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What department approves vaccines in the US?
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USDA Center for Veterinary Biologics
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Where should ADEs for vaccines be reported?
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manufacturer
USDA CVB |
