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22 Cards in this Set

  • Front
  • Back

Vaccination

The act of giving a vaccine

Immunization

Rendering an animal protected against a certain disease

Core vaccines

Should be given to all animals of a species

Non core vaccines

Should only be given to animals at increased risk of exposure

Antibody titer

A blood test to measure the amount of antibodies to a specific antigen, used to determine if an animal has enough antibodies to be protected against the antigen

Vaccine failure

Animal still acquires the disease even thoughit was vaccinatedLikely not the vaccine but something went wrong with the boats response to the vaccine

Patient risk variables to consider before vaccination

Age


Health status


Geographic prevalence of disease


Risk on exposure


Pathogenicity of disease


Maternal antibody interference


Nutritional status


Chronic stress


Do the benefits outweigh the possible risks

Steps to vaccine administration

1. Examine pets to ensure they are healthy and able to receive vaccine


2. Clean the correct site of administration (do not use alcohol)


3. Administer vaccine as recommended by the manufacturer


4. Document the vaccination in the pets file

Routes of administraion

1. Injection


2. Intranasal


3. Orally

Types of vaccine administration

1. All animals (regardless of age, weight, breed or gender)


2. Systemic response (whole body):inject or eat


3. Localized response: given in eyes or nose


4. Animals must be healthy when vaccinated, otherwise the vaccine wont be affective or they become ill from the vaccine

Inactivated vaccine (killed)(non-infectious)

1. contains adjuvants


2. Advantages: unlikely to cause disease, safe, stable


3. Disadvantages: needs repeated doses, possible reactions, poor response

Adjuvants

substances that enhances the immune response by increasing the stability of the vaccine in the body

Attenuated (modified live)

1. Microorganism in the vaccine loses virulence but is still able to replicate within the patient


2. Advantages: longer immunity, better efficacy, quicker stimulation


3. disadvantages: can cause abortion, can produce mild form of the disease, can shed in the environment, proper handling/storage is critical

Live

Fully virulent


2. Advantages: fewer doses are needed, lasts longer, inexpensive


3. disadvantages: residual virulence that requires careful handling

Recombinant

1. a gene or antigen of a microorganism is removed and inserted into a non-pathogenic microorganism


2. Advantages: fewer side effects, highly effective immune response, varied routes of administration, safety, impossible to produce the disease it is designed to prevent


3. Disadvantages: most costly

Vaccine failure may be due to:

-Maternal antibodies


- Need more time to develop immunity


- Contracted a different strain than they were vaccinated for


- Physical damage to the vaccine


- Incorrect administration


-Non-adherence to vaccine schedule


- Breed variations


- Immunocompromised individual


- Concurrent infection/fever


-Nutritional status (malnourished)

What to do if a dog has had a previous reaction

-Split the vaccines up in the future


-Vaccinate less frequently


-Use a different brand


-Give a steroid or antihistamine beforehand

Types of reactions to vaccines

Normal - C/S - Lethargic, anorexia, localized swelling/pain at site for 1-2 days, mild fever


- Tx - Monitor, should resolve on own


Anaphylaxis - C/S - Vomiting, diarrhea, swelling of face, pruritus, repiratory distress, hives, pale mucous membranes, weak, shock, seizure, coma, death


-Tx - IV fluids, oxygen, antihistamine, steroids, epiniphrine


- Most common with killed vaccines



Vaccine handling guides

-protect vaccines from temp extremes (most store in the fridge)


-protect vaccines from UV light


-Use only diluents supplied by manufacturer for specific product


-Do not mix vaccines in the same syringe unless recommended by manufacturer


- Vaccines should be used as soon as possible after reconstitution


-Use the entire ecommended dose of vaccine


-Multiple dose vials have an increased risk of contamination


- Use proper animal restraint when administering


- Use route of administration recommended by manufacturer


-Clean the injection site of any dirt or debris


- Document vaccine administration in medical record

What should be documented in medical record for vaccinations

-Vaccine type


-name


-manufacturer


-serial/lot #


- expiration date


-date of administration


-route of administration


-administration site

Soft tissue sarcomas

difficult, deeply rooted tumors of cats.



Fibrosarcoma

-most common of the injection site sarcomas


-tumor that does not usually spread throughout the body


-it digs in deeply and widely in a localized area


-After surgical removal, it is notorious for recurring even more aggressively than before