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96 Cards in this Set
- Front
- Back
Continuous flow murmur in infant=?
What else might they have? |
PDA
-mildly accentuated peripheral pulses |
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Endocardial cushion defect in newborn=?
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Down's syndrome (AV septal defect)
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TMT of amebic liver abscess?
Dx Test? Story |
Metronidazole
-trophozoites (protozoa) in stool exam, serology, liver imaging (look for mexico trip w/ bloody diarrhea from colon infxn now w/ liver pathology) |
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What is seen in Charcot's Joint?
What causes it? |
XR foot shows: loss cartilage, osteophyte development, loos boney fragments, may have effusion
-Neurogenic arthropathy (nerve damage): in diabetic nephropathy, syringomyelia, B12 def, tabes dorsalis, spinal cord injury -TMT w/ mechanical device/special shoe assist in weight bearing |
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Use of raloxifene?
Contraindication? |
SERM (selective estrogen receptor modulator=mixed agon/antag of ER, agon in bone, antagon in breast/vag)-decreased risk breast ca/vag ca, TMT of osteoporosis (1st line, but less effective than bisphosph and estrogen)
-DVT!!! -may cause hot flashes, leg cramps |
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When do you give demsopressin preoperatively?
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Pt w/ mild hemophilia A, factor deficiency->increased factor VIII and vWF release
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Apgar scoring?
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appearance/color: 0 blue, 1 pink except extrem, 2 pink
pulse: 0 <60/asystole, 1 60-100, 2, >100 Grimace/reflex/irritable: 0 no response, 1 grimace/feeble cry, 2 sneeze/cough Activity/tone: 0 none, 1 some flexion, 2 active moving Resp: 0 none, 1 weak/irregular, 2 strong |
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Order of newborn care in delivery room:
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1. suction mouth and nose
2. clamp/cut umbilical cord 3. dry and keep warm infant 4 rubb heals/stimulate to stim crying/breathing 5. assess APGAR at 1min 6. Eye Care w/ silver nitrate and erythromycin/tetracycline 7. Vitamin K IM 8. Hep B vaccine (later) and HBIG (if HBsAg+ mom) |
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TMT of mastitis?
What if abscess? Most likely organism? |
abx (dicloxacillin or cephalosporins), analgesics, continue breast feeding from it (decreases progression to abscess)
-I & D (if fluctuance noted) -S. aureus |
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What is beriberi?
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Thiamine deficiency->fulminant cardiac syndrome w/ cardiomegaly, tachy, cyanosis, SOB, vomiting in NEWBORN), in adult: dry only has peripheral neuropathy w/ sensory/motor impairment extrem, Wet has both cardiac (CHF + cardiomyop) w/ nerve findings
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Findings in riboflavin def?
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Either from 3rd world or have malabsorptive dz/anorexia nervosa: sore throat, cheilitis, stomatitis, glossitis, seborrheic dermatitis, hyperemic edematous OP
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What is scurvy?
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vitamin C (ascorbic acid def): impaired collagen synthesis and damaged connective tissue: ecchymoses, petechiae, bleeding gum, arthralgias, impaired wound hearing, coiled hair, Sjogren's syndrome!!
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What are odd vit A def findings?
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Bitot spots (dry silver gray plaques on bulbur conjunctiva), cloudy cornea (keratomalacia), dry skin and conjunctiva (xerosis conjunctiva), follicular hyperkeratosis on extensors/butt/shoulder
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Best long-term relief tmt for duodenal ulcer?
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abx (CAP) + PPI: since all duodenal ulcers are caused by H. pylori so no relief until that is taken care of (even if ETOH drinker)
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What is the murmur of IV drug user endocarditis?
What other findings? |
Tricuspid Regurg: holosystolic murmur increase w/ inspiration
-septic pulm emboli->cough, chest pain, hemop, round alveolar infiltrates on CXR -immune-complex glomerulonephritis->ptnuria -Janeway lesions (painless/flat), osler nodes (painful/raised), roth spots (eyes), splinter hemorrhage, conjunctival petechiae -From Staph aureus (more common in HIV pts) -Dx w/ blood cx, TTE, TEE -empiric TMT: vanc/gent: if MSSA: ox/clox/diclox, if MRSA: vanco |
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parodoxical split S2=?
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P2 b4 A2 during expiration= aortic stenosis, LBBB (LV outflow obstruction)
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TMT for PCP in HIV/ADS?
What if sulfa allergy? |
BACTRIM!
-add STEROIDS if PaO2 <70, A-a gradient >35 -sulfa allergy: give pentamidine instead of bactrim (will know PCP from low O2sat/hypoxia out of proportion to CXR findings of bilat interstitial infiltrate, hi LDH) |
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What is enthesitis?
Where do you get it? What does it equal? |
pain/inflammation at sites tendon/ligs attach to bone
-achilles tendon/HEEL, iliac crests, tibial tuber -Ankylosing Spondylitis |
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Triad of ectopic pregnancy?
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amenorrhea, abd pain, vag bleeding, esp in pt w/ hx PID
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Solitary ring enhancing lesion on brain CT w/ fluid collection in L maxillary sinus, pt hving neuro sx=?
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brain abscess from anaerobic bacteria and aerobes and Bacteroides from maxillary sinusitis
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6mo old child w/ poor feeding, fussy, bulging anterior fontanelle, wide suturs, growth chart w/ rapid enlarging head circumference=?
Dx Test? TMT? |
Hydrocephalus (may also have vomiting, decreased activity, scalp veins)
-CT scan w/ dilated ventricles or MRI (better in u/s, only U/S if <6mo since need wide open fontanelle) -shunt from ventricle to peritoneum/pleura for CSF drainage |
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Differentiate tension pneumo from shift of ET tube to R main bronchus?
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tension pneumo will also have hypotension, tachy from impaired RV filling (since compressing the mediastinum)
-Shift ET tube causes atelectasis L lung so will have decreased breath sound, cough, down O2sat, but no change in BP or HR |
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Swelling cheeck and puruelent saliva postop in pt w/ dementia=?
What could have prevented this? |
Parotitis (most likely staph aureus)
-fluid intake and oral hygiene |
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Brocas vs Wernickes aphasia?
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Brocas: expressive aphasia (difficulty forming words/speaking, frustrated by it can understand)->dominant frontal lobe
Wernickes: receptive aphasia->superior temporal gyrus |
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Steps for acute preterm labor 24-36wga?
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Deliver if: pree/eclampsia, maternal cardiac dz, cervix >4cm, hemorrhage/abruptio/DIC, fetal death, chorioamniotis
1. betamethasone (systemic corticosteroids) to prevent RDS (resp distress synd) 2. Tocolysis (mg sulfate, CCB, terbutaline) w/ goal of stopping delivery for at least 48hrs for steroids to work |
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What does SVT mean?
How do they look? What are paroxysmal SVT (PSVTs)? Workup? |
any tachy that is above the His-bundle (sinus tach, afib, aflut, multifoc atrial tach, AV nodal reentrant tach, AV reentrant tach, junctional tach)
-narrow QRS <120ms, rate 160 or >, burried P waves or inverted P waves appearing as spikes on QRS -AVNRT, AVRT, atrial tach, junctional tach Steps: evaluate to identify by vagal maneuvers (carotid sinus massage, vasalva, eyeball pressure) or IV adenosine)->will slow conduction via AV node unmaksing "hidden" P waves in a tachy or aflut AND will terminate AV node-dependent arrythmia (AVNRT) |
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TMT of PVCs in clinic?
What about premature atrial beats |
Observation. If sx or worens-> TMT w/ b blockers
observation (never require tmt always benign) |
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what is R heart failure in pt w/ COPD or pulm dz?
-what to look for? |
Cor pulmonale (clear lungs w/ prominent RV and pulm artery, flattened diaphragms in copd, JVP, RV heave, hepatomegaly, ascites, edema)
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Steps in caustic ingestion?
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1. ensure breaths sounds/patent airways
2. upper GI endoscopy w/in 24hrs to assess injury do NOT do NG lavage or try to neutralize it, steroids do NOT help |
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Child w/ steatorrhea, failure to thrive, neonatal jaundice, clubbing, wheezing=?
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CF (also anemia, heat intolerance, steatorrhea from pancreatic insufficiency, rectal prolapse)
-do sweat chloride test x2 followed by gen studies -give hi cal diet, pancreatic enzyme replacement, fat sol-vitamins -watchout for gallstones, cirrhosis, portal htn, pancreatic fibrosis |
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Most common cause of hypercalcemia in ambulatory pts vs hospitalized pts?
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primary hyperpth
malignancy |
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What are physical findings in rickets and xr findings?
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craniotabes (ping pong ball sensation on head bones)
rachitic rosary (enlarged costochondral junctions) thick wrist and ankles Harrison groove (horizontal depression lower border chest) large anterior fontanell XR w/ cupping and fraying of distal ends long bones, double contour along lateral outline radius -<2mos age: vit D and sunlight, after just po vit D |
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Describe heme findings ALL
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hi WBC, hi blast %, low plt, low hgb, blasts have PAS stain w/ TdT immunostaining
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Describe histo in burkitt lymphoma
what is it associated w/ TMT? |
Mature B Cells: "starry sky appearnace"
-EBV mono (pt w/ mass on mandible or abd viscera) -hi dose chemo very effective |
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27yo M w/ recurrent nosebleeds, ruby colored papules on lips blanch to pressure, and hi hct.
ML Dx? Cause? Findings? |
Hereditary Telangiectasia (osler-weber-rendu syndrome)
-aud dom -telangiectasias, recurrent epistaxis, discolored skin, AVMs (lung, liver, brain) that shunt blood from R to L heart (AVM in lung)->chronic hypoxemia->reactive polycythemia |
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Difference of Rotors Syndrome and Dubin-Johnson's?
Hint=? Dx Test? |
Dubin Johnsons does cause black liver (hepatocytes), Rotors does not
-Sephardic Jews! -icterus triggered by stress, infxn, OCP, pregnancy =Test: >50% dbili, test w/ urine coproporphyrin I hi |
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Most common cause of lymphadenitis (tender erythematous enlarged lymph node)?
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staph aureus, 2 strep pyo
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violaceous unilateral lymph node 3cm nontender=?
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MAI (affects kids <5yo)
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Cause of carpal tunnel in hypothyroidism?
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accumulation of matrix substances from myxedema (deposition of mucopolysaccharides)
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Describe back pain of metastatic dz compared to DJD?
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constant and worse at night wherease DJD is better w/ rest, worse on activity
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4mo old M infant w/ lethargy, poor feeding, pallow, webbed neck, shielded chest, cleft lip, systolic ejection murmur, Hgb 8, retic 0.4%, MCV 104
ML Dx? Criteria? |
Diamond-Blackfan Syndrome (congenital hypoplastic anemia)
-macrocytic anemia, low retic count, congenital anomalies (from defect of erythroid progenitor cells causing increased apoptosis) -give steroids |
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differentiate esophageal dysmotility of scleroderma from achalasia?
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Achalasia: absent/decreased peristaltic waves w/ INCREASED LES TONE
Sclero: sticking sensation throat/dysphagia, absent peristaltic waves lower 2/3 w/ DECREASED LES TONE |
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older person w/ dark purpurle ecchymotic skin areas over dorsum of both arms=?
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Senile Purpura: ecchymotic lesion from perivascular connective tissue atrophy in old age (discoloration/brownish purple from hemosiderin deposits), benign
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Infant w/ oliguria and midline palpable mass=?
-Dx test? |
posterior urethral valves
-do voiding cystourethrogram |
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Hypospadias =?
assicated w/? don't do what? |
ventral surface opening of urethra (down)
-cryptoorchidism, inguinal hernia -circumcise |
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Epispadias=?
Associated w/ what? |
urethral opening dorsal surface (up, pee in eye)
-bladder exstrophy (is bladder outside body) |
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neonate w/ hyrdocele
TMT? |
nothin
will resolve w/in 6mos |
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description of actinic keratoses.
Tell me about it? TMT? |
erythematous papules w/ central scale from hyperkeratosis, may start flat w/ sandpaper like texture but become elevated as "cutaneous horns" no more than 10mm
-seen in 40-60yo w/ excessive sun exposure face, ears, scalp, dorsa arms/hands -light microscopy w/ thickened epidermis, abnormal keratinization, thickened stratum corneum/hyperkeratosis, may have atypia->premalignant w/ risk of squamous cell ca (based on how big it gets) -must treat w/ removal or topical 5FU or imiquimod (also used for molluscum contagiosum & condyloma acuminatum/warts) |
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What to do before starting trastuzumab?
What is it used for? |
echo for cardiac function (EF >55%) since has risk of cardiotoxicity w/ chemo
-HER 2/NEU in breast ca, is ab to that ER receptor |
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When to anticoagulate vs. do more dx steps for PE?
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The Wells score:[13]
clinically suspected DVT — 3.0 points alternative diagnosis is less likely than PE — 3.0 points tachycardia (heart rate > 100) — 1.5 points immobilization (≥ 3d)/surgery in previous four weeks — 1.5 points history of DVT or PE — 1.5 points hemoptysis — 1.0 points malignancy (with treatment within 6 months) or palliative — 1.0 points If >4: PE likely: hep infusion, then spiral CT, if 4 or less: other way around |
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5day old infant w/ bloody diarrhea and vomiting, stool exam w/ rbcs and eosinophils=?
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Milk ptn intolerance: hypersensitivity to cow's milk ptn that usually occurs when given cow's milk but can occur if breast fed (look for hx of atopic dz in family)
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Chlamydia screening guidelines?
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annually in sexually active <=25 or women >25 w/ new or multiple sex partners
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TMT for asymptomatic chlamydia (nucleic acid amp negative for gonorrhea)?
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single dose azithromycin or doxy course.
(have to treat for gonorrhea if use gram stain to dx instead of nucleic acid amp since less sensitive) |
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How to dx vasovagal syncope in pt w/multiple recurrences (that 24yo white F who faints in stressful sits)?
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upright tilt table testing w/ or w/out pharmacologic provocation (isoproteronol)->do if recurrent syncopal episodes
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TMT of cluster headache?
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1. 100% O2 (best abortive tmt, will not work on migraines)
2. subq sumatriptan 3. ergotamine ppx w/ VERAPAMIL! |
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pregnant F w/ Ucx showing 150000 colonies e. coli but asx
What to do? |
Concern for pyelo (>100000 midstream clean catch) that can lead to sepsis, preterm (increase risk in preg since stasis urine)
-TMT w/ amoxicillin, ampicillin, nitrofurantoin, cephalexin |
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Pregnant pt w/ severe vomiting.
STEPS? |
1. ABCs w/ fluid resucitation
2. bHCG (to r/ow hydatidiform mole or chorioca/gest trophoblastic dz (triad of enlarged uterus, hyperemesis, elevated bHCG >100000)) 3. U/S |
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Criteria for hyperemesis gravidum?
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starts wk 4-10, loss of >5% pre-pregnancy weight, ketonuria, persistant vomiting (will see elevated amylase lipase from salivary gland from vomiting, and up LFTs mildly)
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What are typical findings in newborns?
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mammary gland enlargment and nonpurulent vaginal discharge (may be blood-tinged)
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When do you do a buccal smear?
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dx Turner's Syndrome
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What can cause pna and diarrhea in immunocompromised pop?
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CMV (pneumonitis + GI ulcers->diarrhea and abd pain, arthralgias, myalgias, esophagitis)
Can be seen mos after bone marrow transplant pts |
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10yo boy w/ multiple episodes LOC while playing, immediate regain of consciousness w/out confusion, has impaired hearing since birth, fam hx of cousin w/ sudden cardiac death.
ML Dx? TMT? |
Jervell-Lange-Nielson Syndrome=congenital long QT syndrome=Torsades de Pointes (look for pt w/ syncopal episode w/ NO post-ictal period, and hearing impairment and fam hx.)
-Propranolol immediately (if sx, propranolol + DDD pacemaker) |
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What drugs can you take/not take during stress test?
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48hrs b4 hold: bblockers, ccbs, nitrates
48hrs b4 vasodilator stress: dipyridamole 12hrs b4 vasodilator stress: caffeine Continue: ACEi/ARB, digoxin, statins, diuretics |
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Acute Migraine tmt?
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Antiemetics (prochlorperazine, metoclopramide, chlorpromazine)
Triptans (only useful early b4 severe sx, b4 vomiting, photophobia) PPx w/ propranolol |
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12wk old infant w/ umbilical hernia=think what?
Describe findings? TMT? |
Congenital hypothyroidism (cretinism results)
-normal at birth (from maternal hormones present), then develop apathy/no emotion, hypotonia, weakness, large tongue, sluggish, abd bloatin, UMBILICAL HERNIA, jaundice, resp distress, noisy resp, hypothermia, macrocytic anemia (from hypoxemia) -screening mandated in all states w/ serum TSH, T4 -Levothyroxine |
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long-term neurologic sequelae of bacterial meningitis?
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1. hearing loss
2. loss cognition 3. seizures 4. mental retardation 5. spasticity or paresis |
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1mo old infant to ED w/ projectile vom, fair hair and skin, eczematous rash, urine w/ mousy odor
ML Dx? Cause? Dx Test? TMT? |
Phenylketonuria (eczema rash/dermatitis, mental retard/seizure, growth retard, musty body odor, fair skin, normal at birth from maternal products)
-lack of phenylalinine dehydroxalase so phenylalanine builds up and tyrosine becomes essential -blood phenylalanine levels or Guthrie test:urine coloration for phenylalanine metabolic products -Diet lo in phenylalanine (no hi ptn, aspartam, nutrasweet) |
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Define an innocent murmur.
TMT? |
systolic ejection, less than or equal II/VI, varies w/ position, no other sounds, child asx
-observation |
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What causes zenker's diverticulum?
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Not GERD! It is due to upper esophageal sphincter dysfunction and esophageal dysmotility causing incoodrination leading to herniation of mucosa via a pulsion mech, in pts>50
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Initial management of suspected infective endocarditis?
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Draw blood cx then start empiric abx (vanco/gent)
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Triad of a glucagonoma?
Where does it occur? |
hyperglycemia (pt may describe need to drink a lot from hypergluc), necrotizing dermatitis!, weight loss
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What are the uncommon presentations of RA (2)?
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Felty: RA, splenomegaly, Neutropenia
Caplan: RA, pneumoconiosis, Lung nodules |
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Pt P-ANCA + w/ bloody diarrhea and low back pain w/ sacroiliac inflammation.
ML Dx? |
Ulcerative Colitis: will have e. nodosum, p-anca, pyoderma gangrenosum, arthritis (similar to AS),episcleritis, cholangitis as extracolonic findings
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What electrolyte changes cause hyperactive DTRs?
When does this typically happen? |
Hypocalcemia and hypomagnesimia: typically after surgery w/ lots of RBCs given (citrate can bind to ionized calcium decreasing its total) Remember hypoCa=Tetany
Remember: Na=weak & delirious K=weak and paralyzed Mg=Ca |
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When to think tropical sprue?
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chronic diarrhea, pt from endemic area, malabsorption (B12, folate=megaloblastic anemia), borborygmi, hyperactive bowel sounds
Dx w/ bx showing blunt villi and lots of eosinophils/lymphocytes/plasma cells et. |
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What is best to influence long term prognosis of STEM?
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restore coronary blood flow (PTCA or thromoblytic)
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Summarize differences of mineralization in rickets vs. osteomalacia vs osteogenesis imperfecta vs osteoporosis vs pagets
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Rickets: defect mineralization bone and cartilage
Osteom: defect mineralization bone only Osteo I: defective formation collagen (type 1=bone, tendon, ligament, skin, sclera) give bisphosphonates OsteoP: low bone mass and normal mineralization Pagets: disordered skeletal remodeling |
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What is Friedreich ataxia?
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Aut recessive, b4 22yo, spinocerebellar ataxia w/ neuro (gait ataxia, falling, dysarthria) w/ concentric hypertrophic cardiomyopathy, DM, scoliosis, pes cavus, "hammer toes" (death by cardio and resp)
-"Fiedrich is Fratastic (frataxin): he's your favorite frat brother always stumbling, staggering, falling, but big hearted and big toed |
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What is the main long term complication of vesicoureteral reflux?
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renal scarring->can cause ESRD in young children
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What is respiratory quotient on ventilator?
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CO2 produced: O2 consumed per time
=1 if mostly carbohydrate major nutrient (>1 if excess) =0.8 if protein =0.7 if fatty acid |
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TMT of GBS=?
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IVIG or Plasmapheresis
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Screening for diabetes in pregnancy?
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-If pregestational DM: switch to insulin (NPH and lispro), do EKG, 24hr urin for baseline renal collecting Cr clearance and ptn, HbA1C, eye exam
-if normal: at 24 and 28wga, give 50g 1hr oral glucose tolerance test (OGTT)->if >140->do 3hr 100g OGTT, if any level > than expected=Gest DM: tmt 1st line w/ diet and excercise->if fails to gets fasting <95 or 1hr postprandial <140: start insulin w/ NPH/aspart |
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McCune-Albright Syndrome?
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4Ps: precocious puberty, Polycystic ovaries, Pigmented cafe-au-lait spots, Polyostotic fibrous dysplasia of bone
think "the young girl w/ big boobs and cafe au lait spots" |
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TMT of UTI in pregnancy (drugs contraindicated?)
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Nitrof, amoxicillin, amox-clavulonate, cephalexin
Contrai: tetracyclines, fluoroquin, bactrim |
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Stages of labor?
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Stage 1 (onset labor->fully dilated): 20hr prima, 14hr multiparous (broken into latent and active phases)
-Latent: 0-4cm dilation (variable, 6hr prima, 4hr multi) -Active: 4-10cm dilation (1cm/h4 prima, 1.2cm/hr multi) Stage 2: fully dilate->baby delivered (30m-3hr, 5-30min) Stage 3: baby->placenta (0-30min both) |
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Signs of placental separation?
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In stage 3: gush of fresh blood, umbilical cord lengthens, uterine fundus rises, uterus becoming firm
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Define protracted cervical dilation?
Arrest of cervical dilation? Arrest of fetal descent? |
Protracted: less than 1cm or 1.2cm/hr in primi and multi
Arrest dilation: no dilation 2hrs arrest descent: no descent 1hr (add an hour to these if epidural anesthesia) |
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What is the proper presentation of fetus in delivery?
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LOA: Left occipitoanterior position
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What are adequate contractions in delivery?
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3-5contractions lasting 40-60sec per 10min
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Workup of asymptomatic primary hyperparathyroidism?
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Need surgery if: serum Ca>1mg than max limit OR <50yo OR bone min density <T-2.5 anywhere OR reduced renal function eGFR<60ml/min
-If need surgery: do sestamibi scan (if negative or equival->bilat neck exploration w/ intraop PTH level and gamma probe, if +scan w/ adenoma->resect) |
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Differentiate neurofibromatosis 1 and 2
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1: cafe au lait, macrocephaly, short stature, feeding problems, learning difficulty, later: fibromas, neurofibromas, Wilms tumor, leukemia, pheocrhomo
2: hilateral acoustic neuromas, cataracts, and neurofibromas |
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When thinking tumor in abdomen palpable in child, what to and how to differentiate?
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<1yo: neuroblastoma (crosses midline, has urine metabolites of catecholamines, HTN, fever hepatomegaly, ewight loss)
2-5yo: Wilm's (HTN, HEMATURIA, abd pain, vomit) |
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Where do medulloblastomas vs astrocytomas occur?
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medulloblastoma: cerebellar vermis
astroctyoma: cerebellar hemispheres |
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Conotruncal abnormalities (truncus arteriosus, tet of fallot)=what congenital thing?
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CATCH-22 syndromes: DiGeorge and velocardiofacial syndromes
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What should be added to breast milk in all premature babies?
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iron supplement
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What should you do if pregant F has chronic hepatitis 2/2 hep C virus?
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Vaccination against hep A and Hep B! (both are safe in pregnancy)
-breast-feeding is safe if hepC infected mother |