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36 Cards in this Set
- Front
- Back
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INC Leukocytes w/ DEC Leukocyte Alk Phosphatase
Dx? |
CML
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Pregnant woman w/ APLA, how do you tx?
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LMWH
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25 you nocturia w/ DEC fluid intake. No signs of UTI.
Dx? |
Hyposthenuria in sickle cell pts
(occlusion of the vasa recta) |
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What electrolyte abnormalities are seen in Tumor Lysis Syndrome?
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INC Ph+
INC K+ INC Uric Acid DEC Ca++ bc of INC Ph+ binding PhUK INC, Ca++ DEC |
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What is odansentron
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Seratonin antagonist, used tot x CTX induced nausea.
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RBC w/ single blue inclusion seen by wright stain.
What does this person have? |
This is a Howell Jolly body, seen in DEC fxn/ absent spleen
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55 yo infused w/ packed RBC,
c/o tremors, fells chilly. Temp 100.3, HR100 Symptoms resolve 3 hrs later -What was the cause? -How do you prevent it? |
This is a febrile transfusion rxn.
-Ab in pts blood reacts w/ donor leukocytesdepletion -Prevent w/ leukocyte depletion ex. washing, frozen deglycerolyzed rbcs |
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WHy do some SLE pts have INC thromboembolic events?
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B/c of Lupus anticoagulant (APLA) in 10% of SLE pts. It is a IgM/G that binds to phospholipids in the assay measuring PTT. INC PTT indicated presence of APLA
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IMP SE of traztuzumab?
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CTx- Dilated cardiomyopathy
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Short 7 yo w/ hypopigmented skin freckles c/o ear pain.
Labs: DEC all cell lines Dx? |
Fanconi's Anemia
-BM Failure -DEC growth -Ear Compaints -AR |
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Which vaccine is a capsular polysaccharide?
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Str. pneumo
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Why does phenytoin cause INC MCV?
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DEC Folate.
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Which lab value is used to dx PCV?
-At what age is polycythemia normal? |
HCT >65%, can have PCV if <65%
1st 12 wks of life PC is normal. After that abnormal |
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What is indicates poor prognosis in CLL patients?
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Thrombocytopenia
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Fragile broken Leukocytes
Dx? |
These are smudge cells seen in CLL. Pts are usually assymptomatic at this point.
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What do you give a stage 4 cancer pt with pain?
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Acute - morphine
Chronic- Fentanyl Patch |
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Leukocyte alkaline phosphatase is DEC in ___________?
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CML
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Can you switch a HIT pt to LMWH?
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No, bc a further rxn can create IgG Ab to heparin
Note: HIT1 -2 days after, non-immune HIT II 4-10 days (II) Is Immune |
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How do you tx low grade malt lymphoma?
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Omeprazole,
Clarithromycin, Amoxicillin |
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No EPO in urine
Dx? |
PCV
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Anemia w/ hepatic vein thrombosis.
Dx? |
Paroxysmal Nocturnal Hemoglobinuria
-No CD55/59 on RBC-->RBC attacked by complement |
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Tx homocystenemia?
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B12
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Tdt (+)
PAS (+) Dx? |
ALL
>25% blasts in the marrow -Lymphocytes contain PAS in the cytoplasm -Tdt (+) in >95% of Pts |
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75 s/p surg for prostat cancer.
p/w: back pain, imbalence, DEC lower B/L lower extremity. Brisk lower tendon reflexes, weak rectal tone. NSIM? |
Dexamethasone
Spinal cord compression. Give Dexamethasone to reduce swelling of the thecal sac |
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14 yo boy w/ DEC breathing through nostrils. 1 episode of epistaxis. Visible mass in L nostril.
CT: erosion of bone MC Dx? |
Juvenile Angiofibroma (JNA)
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Smoker w/ ear pain and lump in neck. PE: U/L submandibular mass w/ 3cm diameter.
Most likely Dx? |
Squamous cell carcinoma, the majority of head and neck cancers are squamous cell
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What level is considered neutropenia?
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Neutrophils <500cells/mm3
(Absolute ct) |
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Pt has INC Ca++, stomach ulcers.
Which condition do u suspect? |
MEN I
This is a presenttion of Zolliger Ellison (Pituatary/Parathyroid may be involved) |
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How does hydroxea help sickle cell pts?
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INC fetal Hb levels.
DEC pain crisis |
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What is the tx for hairy cell leukemia?
What stain is used in HCL? |
TX is cladribine
Stain- tartrate resistant acid phosphatase TRAP |
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Pt w/ newly diagnosed:
-Hepatomegaly -Diabetes -Arthropathy What do u suspect? |
Hemochromatosis
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What is the cause of anemia in pts tx w/ EPO
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DEC Iron b/c of erythropoesis.
Pts on EPO should receive Iron supplementation |
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Tx of sickle cell pt with stroke?
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There is no tx for the stroke but the pt should have an exchange transfusion to DEC any further sickle cell damage
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(+) alpha-naphtylesterase indicates?
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AML
-Dramatic onset -Bleeding gums/nose -Weigh loss -Rare: 15% of leukemias |
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21 yo black w/ fever, jaundice, abdominal pain and dark urine.
Dx? |
Heinz bodies are pictured.
Pt suffers from G6PD Hb is stained by methylene blue |
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Lmphocytosis + Smudge cell
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CLL
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