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16 Cards in this Set
- Front
- Back
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Which atypical antipsychotic is most likely to cause extra-pyramidal SE's? Which is least likely?
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Reserpine is most likely b/c it's directly anti-dopamine (prevents loading in vesicles)
Clozapine is least likely b/c it's a D4 blocker (specific) HOWEVER can cause life-threatening agranulocytosis |
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What causes an S4??
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A stiff ventricular wall = Sudden rise in EDVP caused by atrial contraction against a ventricle that has reached the limit of compliance.
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What acid-base problem occurs w/ acute ASA intoxication?
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First, an acute respiratory alkalosis (d/t increased respiratory drive)
Second, an additional metabolic acidosis d/t accumulation of organic acids (ASA interferes w/ TCA) |
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What drugs can cause focal to massive hepatic necrosis??
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Liver HAVAc:
- Halothane - Amarita phalloides - Valproic acid - Acetominophen |
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What are the live attenuated viral vaccines?
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1) Smallpox
2) Yellow Fever 3) Chickenpox 4) Sabin (Polio) 5) MMR Small Yellow Chickens in the SuMMeR |
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What are the killed viral vaccines?
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RIP Always
1) Rabies 2) Influenza 3) Polio (Salk) 4) HAV |
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What are the killed Bacterial vaccines?
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1) Anthrax (Bacillus)
2) Cholera (Vibrio) 3) Pertussis (Bordatella = Whooping cough) 4) Plague (Yersinia pestis) |
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What are Phenelzine and Selegiline and how are they different?
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Both MAO Inhibitors used for atypical depression, anxiety, and hypochondriasis;
Phenelzine is non-selective; Selegiline is MAO-B Both can cause hypertensive crisis following consumption of foods high in tyramine (cheese, wine, sausage) |
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What is adalimumab?
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It's an anti-TNFα mab used in the treatment of Rheumatoid arthritis
(also used = infliximab, etanercept) |
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What kinds of drug interactions does Niacin have?
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- VASODILATION: can cause postural hypotension in those taking vasodilators for hypertension.
- INSULIN RESISTANCE: sometimes manifesting as acanthosis nigricans; need to increase diabetic medications - URIC ACID: can cause increase, so patient w/ Gout should be cautious |
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What is Plummer Vinson syndrome?
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Esophageal problem; triad:
- Dysphagia (d/t esophageal webs) - Glossitis - Fe-deficiency anemia |
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What dz is a/w fatigue, dysphagia, and koilonychia (spoon nails)?
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Iron deficiency anemia
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What is Diphenoxylate?
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An opiate used to tx diarrhea (slows motility)
- paired w/ atropine = LOMOTIL - atropine SE's (dry mouth, blurry vision, nausea) prevent abuse of the opiate (high doses give euphoria and dependence) |
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What causes progressive multifocal leukoencephalopathy?
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JC Virus (Papova family)
in immunocompromised → progressive loss of mental fx |
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What causes subacute sclerosing panencephalitis?
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Measles (paramyxovirus; helical, enveloped, RNA)
- certain type of measles that doesn't have the M-protein antigen |
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What is the most specific sign of Left Heart Failure?
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Orthopnea
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