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103 Cards in this Set

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Nabothian Cyst

benign, simple cyst found in cervical region of uterus

Symptoms of Nabothian Cyst

asymptomatic unless very large

Nabothian Cysts are more common in....

women who have been pregnant

Measurement of Nabothian Cyst

< 2cm

Sonographic Appearance of Nabothian Cyst

-simple
-discrete
-round
-anechoic

-simple


-discrete


-round


-anechoic

What is the most common finding on pelvic ultrasound?

Nabothian Cyst

Adenomyosis

inner lining of uterus (endometrium) breaks through muscle wall of the uterus (myometrium)




AKA endo migrates into myometrium

Adenomyosis is seen in what percent of hysterectomies?

70%




(2/3)

In Adenomyosis, the ectopic glands are typically seen how far below the endo-myometrium junction?




(mmt)

2-3mm

2 Causes of Adenomyosis

1. defect/absence of basement membrane at junction


2. endo migration by lymph of vascular channels

Risk Factor of Adenomyosis

uterine trauma




(more common in mature reproductive age patients)

Signs & Symptoms of Adenomyosis

- uterine tenderness (dull, achy pain)


- dysmenorrhea


- dysfunctional menstrual bleeding


- menorrhagia


- uterine enlargement

Dysfunctional Menstrual Bleeding

irregular

Menorrhagia

heavy bleeding for several days

Differential Diagnosis for Adenomyosis

-fibroids


-pelvic congestion syndrome


-endometriosis


-endometrial polyps


-endometrial carcinoma

Treatment for Adenomyosis




(if patient doesn't want Hysterectomy)

-GnRH inhibitors


-Birth control pills


-nSAIDS (steroids)


-Endometrial Ablation


-Uterine Artery Embolization

The only sure Treatment of Adenomyosis is..

Hysterectomy

Fibroids co-exist with Adenomyosis in what percent of cases?

>60%

Sonographic Appearance of Adenomyosis

-rounded enlargement of uterus WITHOUT focal mass
-abnormal heterogenous myometrium
-poor definition of endomyometrial junction


-Doppler: hypervascularity throughout uterus

-rounded enlargement of uterus WITHOUT focal mass


-abnormal heterogenous myometrium


-poor definition of endomyometrial junction




-Doppler: hypervascularity throughout uterus

*Key Sonographic Finding of Adenomyosis

Enlargement of uterus will be greater posterior to endometrium

Sonographically, how can we differentiate Adenomyosis from Fibroids ?

fibroids- will have focal, defined mass &


peripheral vascularity




adenomyosis- no focal mass & diffuse hypervascularity

Which imaging modality is most sensitive to Adenomyosis? What are the disadvantages?

MRI




-cost


-scheduling


-insurance (pre-cert)

Hystersalpingogram (HSG)

radiology procedure that inserts contrast to look at uterus, fallopian tubes & surrounding area

Disadvantages to HSG

- not very specific


- very uncomfortable for patients


- does not always provide diagnosis

Appearance of Focal Adenomyosis

-poorly delineated margins


-may appear as intracavitary polyp

Diffuse Adenomyosis




*most common form

- entire uterus involved




- often associated with endometrial hyperplasia & carcinoma

Fibroids

benign growth of uterus

Fibroids AKA...

leiomyomas


myomas


leiomas


fibromyoma

What is the most common tumor of the uterus & female pelvis?

Fibroid

What is a Fibroid composed of?

smooth muscle


connective tissue

Incidence of Fibroids

20-30% women over 30


more common in African Americans

Cause of Fibroids

idiopathic




(unknown)

What does Estrogen do to Fibroids?

increases!

Why do Fibroids tend to shrink after menopause?

lack of Estrogen

Do we typically see 1 Fibroid, or multiple?

multiple

What do Fibroids cause in the Uterus?

- enlargement


- surface lobularity (bumpy)

What feature do Fibroids have that allow them to be removed with little disruption to surrounding myometrium?

they are encapsulated

Signs / Symptoms of Fibroids

- palpable pelvic mass


- uterine enlargement


- pelvic pain


- dysfunctional uterine bleeding (DUB)

How do Fibroids in the Endometrium affect pregnancy?

- increased risk of miscarriage

How do Fibroids in the Cervix or Lower Uterine Segment affect pregnancy?

can interfere with delivery


-should be closely monitored

3 Types of Fibroids




& their locations in myometrium

1. Submucosal - innermost
2. Intramural - center
3. Subserosal - outer

1. Submucosal - innermost


2. Intramural - center


3. Subserosal - outer

2 Types of Subserosal Fibroids

1. pedunculated


2. exophytic

Submucosal Fibroid

- innermost
- will affect endometrium

- innermost


- will affect endometrium

Which Fibroid is most likely to cause symptoms? What are they?

Submucosal




- irregular / heavy menses

Intramural Fibroid

- center
- do not effect endo unless large
- usually will not have defined borders 
- usually multiple found = enlargement of uterus

- center


- do not effect endo unless large


- usually will not have defined borders


- usually multiple found = enlargement of uterus



What are Intramural Fibroids sometimes defined as?

"Heterogenous Echotexture"


"Fibroid Uterus"


"Diffuse Enlargement of Uterus"

What is the most common type of Fibroid?

Intramural

Subserosal Fibroids

- outer
- distorts outer contour of uterus (lumpy uterus - ecophytic fibroids)
- can become pedunculated

- outer


- distorts outer contour of uterus (lumpy uterus - exophytic fibroids)


- can become pedunculated

Pedunculated Fibroid

- grows outside of uterus with a stalk
- can twist and undergo torsion

- grows outside of uterus with a stalk


- can twist and undergo torsion

Parasitic Leiomyoma

exophytic fibroid in close contact with another adjacent pelvic structure and acts as a parasite on the structures blood supply




- can become detached fromuterus completely

Will vascularity be seen in Fibroids?


If so, where?

yes


- along periphery (ring of fire)

What happens if a Fibroid outgrows it's blood supply?

degenerates

Name the 4 types of Fibroid Degeneration

1. Hyaline - fibrous tissue replaces smooth muscle


2. Cystic - necrosis


3. Calcific - after menopause


4. Red Degeneration - acute, common during pregnancy

What do Fibroids look like on Ultrasound as degeneration, calcification, or growth occurs?

- heterogenous


- hypoechoic to myometrium

Differential Diagnosis for Fibroids

- adnexal mass


- endometrial polyp

How to tell Fibroid from Adnexal Mass

fibroids will have shadowing throughout

How to tell Fibroid from Endometrial Polyp

fibroid


-vascularity around periphery


-shadowing



polyp


-1 single vessel

What will ultimately differentiate Fibroids from Polyps?

Sonohysterography

Where will Fibroids be when visualized Sonographically?

In the MYOMETRIUM

What might Fibroids look like Sonographically?

- variable


- may be focal, hypoechoic mass with hypoechoic rim

Complications of Fibroids

- hydronephrosis


- infertility


- miscarriages


- submucosal / cervical fibroids can obstruct delivery

Treatments of Fibroid

most common - no treatment




If causing symptoms..


- hysterectomy


- myomectomy (fibroid)


- Lupron: shrinks fibroids


- Uterine Artery Embolization

Endometrial Polyp

localized overgrowth of endo tissue




- may be pedunculated, broad-based, thin stalk

Signs and Symptoms of Endometrial Polyps

- usually asymptomatic


- infertility


- PMB


- AUB

Sonographic Appearance of Endometrial Polyps

- focal thickening of endo


- discrete mass


**possible feeder vessel


**polyps DO NOT shadow

Where are Endometrial Polyps located?

In ENDOMETRIUM

Endometrial Hyperplasia

proliferation of endometrial glandular tissue

What percent of Endo Hyperplasia will progress to Endo Carcinoma?

25%

What is the most common cause of AUB?

Endometrial Hyperplasia

Causes of Endometrial Hyperplasia

- unopposed estrogen


- persistent anovulatory cycles


- PCOD


- obesity


- estrogen-producing tumors of ovary

Diagnosis of Endometrial Hyperplasia

- ultrasound @ beginning of hormone cycle


- D&C with thorough path exam

Sonographic Appearance of Endometrial Hyperplasia

- smooth


- homogenous


- echogenic


- maybe cystic changes

Sonographic Measurements of Endometrial Hyperplasia

pre-meno - >14mm


postmeno estrogen - >5mm


postmeno estrogen phase - up to 8mm


postmeno prog phase - decreases

Asherman's Syndrome

adhesions of the endometrium that develop as a result of trauma (c-section, D&C, elective abortion, miscarriage)

What can Asherman's Syndrome result in?

- infertility


- recurrent pregnancy loss




(due to scar tissue)

Which Uterine pathology requires SIS to diagnose?

Asherman's Syndrome

Treatment for Asherman's Syndrome

remove adhesions under hysterscope

Uterine Sarcoma

aggressive, malignant tumor


- poor prognosis if not detected early

What is Uterine Sarcoma difficult to differentiate from?

Degenerating Fibroid

What are some Sonographic clues that would point towards Sarcomas instead of Fibroids?

sarcomas


- local invasion


- distant mets


- increase in size peri / postmeno

What is the most common gynecological malignancy?

Endometrial Carcinoma

Risk Factors for Endometrial Carcinoma

- obesity (2-3x more likely)


- nulliparous (2-3x more likely)


- late menopause


- Hx of polyps


- family Hx


- unopposed estrogen


- Hx of Tamoxifen

If a patient has a History of Tamoxifen AND prior uterine abnormalities, what is their chance of developing Endometrial Carcinoma?

18 fold increase

What 2 things will DECREASE the risk of Endometrial Carcinoma?

1. birth control pills


- 10 year safety net


2. smoking


- decreased obesity


- go thru menopause 1-2 yrs earlier

Statistics of Endometrial Carcinoma

- usually diagnosed 6-7th decade (age 50-60)


- higher prevalence in white women


- higher mortality in black women

Signs / Symptoms of Endometrial Carcinoma

Uterine bleeding !!!!

Treatments for Endometrial Carcinoma

- total hysterectomy


- bilateral salpingo-oophorectomy


- peritoneal fluid aspiration & washing


- lymphadenectomy

Sonographic Appearance of Endometrial Carcinoma

- heterogenous


- irregular / poorly defined margins


- cystic changes


- hydrometra / hematometra


- enlarge uterus


- lobular contour




- subendometrial halo: very distinct = probably localized. borders not distinct = metastatic spread

Which Ultrasound exam is most helpful in diagnosing Endometrial Carcinoma? What is the clear evidence?

Transvaginal




- showing myometrial invasion = clear evidence of endo carcinoma

What are the 2 Uterine Potpourri

1. Arteriovenous Malformations (AVMs)


2. IUD's

Arteriovenous Malformations

communication between vein / artery




(can be congenital OR iatrogenic)

Signs / Symptoms of Arteriovenous Malformation

Dysfunctional uterine bleeding

Why is it important to differentiate Arteriovenous Malformation from other causes of DUB?

Treatment for AVMs is different, less invasive, and more effective

What do IUD's look like on Ultrasound?

brightly echogenic with beam attenuation

Why do we use Transvaginal for IUD's?

- rule out migration into myometrium


- correct location (fundus / corpus)

What may happen if IUD is not placed correctly?

may exist with an intra-uterine pregnancy

IUD's may increase risk of....

- ectopic pregnancy


- PID

First step when experiencing AUB

rule out pregnancy

What do we consider AUB in women over 40 until proven otherwise?

Cancer

How we take Endometrial Measurements

- sagittal


- 'basalis to basalis' / 'functional' to 'functional'


- if fluid is present, measure halves seperate

Saline-Infused Sonography


AKA


Sonohysterography

insert fluid to view




-MUST know uterine position PRIOR to exam


-best to perform ASAP after bleeding

Risks / Contraindications for SIS

- infection


- irregular menses


(if irregular, will prompt menses with 10 day hormone regimen)

Purpose of SIS

1. distinguish who needs hormone therapy vs. invasive procedure to treat AUB




2. differentiate polyps & fibroids