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43 Cards in this Set

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Septic Shock
Infection / Hypotension / Tachycardia / Tachypnea
Decreased sats
Increased capillary permeability
Pulmonary a. cath shows?
CO variable; PAWP: High/normal
SVR: low (<900dynes/cm2)
Cardiogenic Shock
Hx of MI, CAD, HLD
Low CO
High PAWP (RAP)
High SVR (compensates for dec CO)
Hypovolemic shocck
Decreased circulating blood
Low CO
Low PAWP (unique)
High SVR
Extracardiac obstructive shock
tamponade, tension pneumo, massive PE
Low CO
Normal/high PAWP
High SVR
Vascular surgery risks
MI (esp if DM, HTN, prior MI)
Vascular Claudication - management?
Measure ankle/brachial index. If < 1.0, peripheral artery disease is present.
1. Exercise/Diet modification
2. Cilostazol - phosphodiesterase inhibitor
3. Vascular surgeon consult
4. Percutaneous transluminal angioplasty if surgery is not option.
Pericardial Tamponad
SUSPECT!
Beck's Triad: Hypotension, Faint heart Sounds, JVD
- May occur late, post MI
Blood reactions
Acute febrile hemolysis - due to ABO mismatch, presents w/erythema, nausea, pains
Delayed - 3-10days later, mild course w/fever and malaise
Hemochromatosis / etiology and risks
Auto recessive, HFE mutation which interacts w/transferrin and alters iron absorption;

Dx: Transferrin levels most sensitive test
Present in 40s/50s w/elevated transaminases and cirrhotic changes. Cardiomyopathy is 2nd most common, then Arthropathy and skin bronzing.
VSD
Harsh Systolic Thrill, Left Sternal Border; acyanotic; Often young (2month old); echo confirms dx. complications include pulmonary vascular obstruction, CHF; Smaller defects close spontaneously
ASD
Common acyanotic, left-to-right shunt, typically *asymptomatic*. Wide, fixed split S2; Pulmonary hypertension, arrhythmias, heart failure are associated
Coarctation of aorta
Upper body hypertension, lower body hypotension & weak pulses,
PDA
asymptomatic if small; wide pulse pressure, machinery like murmur, apical heave, thrill may all be present.
blood flows directly from aorta to pulmonary artery
Mitral Regurgitation
Holosystolic murmur radiating to axilla
Need TEE. If end-systolic ventricular dimension > 45-55mm, or if EF < 55% --> cardiac surgeon referral
Kawasaki's - pres / tx
CRASH and BURN
Conjunctiva
Rash
Adenopathy
Swelling
Hands and Feet (rash)
Burn = Fever (high and longer than 5 days)
Use high dose asprin and IVIG, get echocardiogram to r/o coronary aneurysms,etc

*Influenza vaccine needed w/in one month, if receiving IVIG (prevent Reye's syndrome)
Post-MI Meds, Activity
Asprin
Beta-Blockers
Avoid strenuous phys activity and sex 1-2 weeks.
Gradually resume aerobic exercise program after that.
Submaximal Gx test before d/c (optional)
Maximal Gx test 3-5 weeks post-MI
Hyperlipidymia Treatment
LDL
HDL
TGs
LDL: statins
HDL: #1 nicotinic acid, gemfibrozil, statin (ranked)
TGs: nicotinic acid / fibrates
(target TGs if over 200, w/fibrates)
diet lowers HDL and LDL; Exercise may increase HDL;
LDL
risk factors,
goals
Risk Factors:
smoking
HDL < 40
hx of MI < 55 in 1st degree
M > 45, F > 55
1 or less: 160; statin at 190
2 or more: 130; 160;
CHD equiv: 100; 130;
Potassium Sparing Diuretics
Spironolactone
Amiloride
Conn Syndrome
Secondary hypertension from hyperaldosteronism, adrenal tumor.
Dx w/imaging of abdomen
A-fib
sx?
tx?
Sx may be present: SOB, lightheadedness, nausea, syncope.

risk:mitral stenosis --> dilated LA
1. Control rapid ventricular response: CCB, BBs, Digoxin; can continue for two weeks w/anticoagulation, then pursue DC Cardioversion
2. If unstable: cardioversion (after TEE)
3. Always: Heparin(Warfarin)

cardioversion can be used in combo with dofetilide, ibutilide, flecainamide, amiodarone, propafenone;
Temporal Arteritis
HA/Vison Changes/Jaw claudication
Dx: clinical, ESR, Bx
Manage: START prednisone if high sus, don't wait!
HOCM
Systolic ejection murmur at RUSB, no resp variation, (+) going to standing & w/valsalva, (-) w/handgrip
Suspect in younger patient
- aortic outflow obstruction is dependent on both preload and afterload. As preload (-) w/valsalva or moving to erect, the murmur increases. When afterload (+) as w/sustained handgrip, the end systolic chamber size increases and outflow obstruction decreases along w/murmur intensity.
AS
Systolic Ejection Murmur; cardiac base or LUSB;
Valsalva decreases preload, which decreases murmur. Standing to sitting increases preload, increasing murmur.
Lightheadedness, decreased exercise tolerance, syncope, angina
Signs of left heart strain: downloping ST segments in I, AVL, V5-6; axis deviation to -60
Murmur increases w/increased preload
Valve area <0.7 is considered critical
MR
holosystolic murmur at apex radiating to axilla.
Increases w/increased afterload (handgrip)
TR
holosystolic murmur at LLSB, increases w/inspiration
Right sided flows are increased with more negative intrathoracic pressures (inspiration)
Hypertension Cutoffs / workup
Stage
1 - 140/90 --> thiazide
2 - 160/100 --> 2 drugs
remember, need TWO readings
Workup - if young (e.g. <40) and extremely high (e.g >150), look for secondary causes before initiating therapy
Infective Endo Prophylaxis Indications
Prosthetic heart valves or shunts
Hx of IE
unrepaired cyanotic congenital HD
transplanted heart
Lead Poisoning
Anemia, irritability, basophilic stippling, homes before 1950, or renovated homes in 60s or 70s;
- get lead level (>70 considered very toxic)
- Dimercapol / EDTA treatment /
- XR Abdomen for Pb in bowel - if present may require bowel decontamination
Aortitis etiology
Salmonella - any diseased portion
Syphillis - aortic bulb
Pericardial effusion - sx/ dx
SOB, Diminished heart sounds, electrical alternans (P and R wave variability), cardiomegaly on XR, and effusion visible on CT
Reentrant v. tach
Cardioversion (w/epi - better than lidocaine) if unstable
Rate control w/beta blockers if stable
V-fib
Unychronized cardioversion
Pericarditis
follows hx of infection; chest pain - mid-sternal and non-radiating, positional and pleuritic,
Diffuse ST elevation / PR depression w/ PR elevation in aVR
Post-MI Meds
Asprin
Beta-blockers
Statin
+/-CCB?
DIC
Low Platelet count
Elevations in PT / PTT

- thrombin values are not useful
- etiology: cancers, infections, anything
Sarcoidosis
multiple organ manifestations - easy bruising, hypertrophic heart w/speckled pattern, CHF w/restrictive pattern, proteinuria, BL carpal tunnel - etc.
Dissecting Aortic Aneurysm
Excruciating CP radiating to Back; CT scan.
Type A- Operate
Type B- Beta Blockers
CHF Drugs to Improve Mortality
Spironolactone, ACE-i, BetaBlockers,
Variant Angina
Substernal chest pressrure, spontaneous pain, hx of similar pain, ST changes (e.g. 1.5mm ST elevations in II,III, aVF);
TREAT w/ MONA +
* Calcium Channel Blockers *
Coronary Syndrome
NSTEMI, STEMI, Unstable angina
NSTEMI
EKG Changes other than ST elevation;
Asprin
Heparin
gp IIb/IIIa inhibitors (aciximab)
Beta Blockers
Infective Endo tx
Vanc if S.Aureus

Vanc, Gent, Rifamampicin for Prosthetic Valves