Usmle Step 1 Q-Bank

Front 1

Pnuemocystic Jerovici

Back 1

-Is a yeast.
1) causes diffuse interstitial pneumonia.
2) common in patients with AIDs
3) CXR- diffuse bilateral interstitial infiltrates.
4) ID- methamine silver stain of lung tissue.

Tx: TMP-SMX, aerosolized Pentamidine(for pts with sulfa drug allergy), Dapsone (Prophylaxis when CD4 drops <200 cells/mL in HIV patients)

Front 2

Ciprofloxacin

Back 2

flouroquinolone

Uses: Urinary tract and GI tract infections by GRAM (-) organisms.

SE = GI upsets & tendonitis

Front 3

Fluconozole

Back 3

Antifungal agent

Uses: Fungal systemic infections (local infection of dimorphic fungi), also indicated in the treatment of Hypercortisolism found in ACTH-secreting tumors and Polycystic Ovarian Syndrome (inhibits hormone synthesis)

Front 4

Terbinafine

Back 4

Antifungal agent

Mechanism: Inhibits fungal enzyme Squalene Epoxidase

Uses: treatment of Dermatophytoses (onychomycosis)

Front 5

Trimethoprim Sulfamethoxazole

Back 5

1st choice prophylactic treatment of Pneumocystis jerovici Pneumonia

Front 6

Diseases

Back 6

SPINAL CORD FINDINGs

Front 7

Amyotropic Lateral Sclerosis (ALS)

Back 7

characterized by both upper and lower motor neuron signs.

Ant horns of grey matter: Damage leads to lower motor neuron type signs = atrophy, muscle weakness, fasciculations.

Corticospinal Tracts: Damage leads to Upper motor neuron type signs= hyperreflexia

Front 8

Polio

Back 8

Characterized by degeneration of Ant horn cells

Front 9

Tertiary syphilis

Back 9

Neuromuscular symptoms due to posterior column degeneration

Front 10

Syringomyelia

Back 10

degeneration of Ant white commissure (pain and temp sensations affected)

Front 11

Guillian Barre Syndrome

Back 11

Characterized by loss of lower motor neurons and sensory nerve function.

Dx is mostly limited to demyelination of peripheral nerves

Front 12

Pernicious Anemia (B12 deficiency)

Back 12

degeneration of posterior columns and corticospinal tracts