Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
|
Where does calcitonin work?
|
Osteoclast inhibits bone reabsorption
|
|
|
What receptor does PTH hook on?
|
Osteoblast
|
|
|
What does PTH releases?
|
IL-1 Osteoclast activating factor
|
|
|
What keeps a check on IL-1?
|
Testosteron and Estrogen
|
|
|
Why do women get osteoporosis?
|
Menopausal Women, breaking bone down since IL-1 is not checked
|
|
|
What enzyme is in the S.E.R. when you have increase P-450?
|
Gamma-glutamyl transferase
- key tests for alcoholics |
|
|
Why does renal dz causes vitamin D deficiency? Caused by Diabetes Mellitus
|
no alpha-1-hydroxylase
|
|
|
Vitamin D from the store, what happens to it before it becomes activate?
|
25-OH D activated in the liver
- 1,25 OH D in kidneys by alpha-hydroxylase |
|
|
Hypervitaminosis D? What happens?
|
Increase Calcium (hypercalcemia), more Calcium in urine causing Stones.
|
|
|
Type I Vitamin D is what?
|
Missing alpah-1-hydroxylase
|
|
|
What is wrong with Type II Vitamin D deficiency?
|
Bad receptors
|
|
|
What is vitamin E main fuction?
|
- Prevent lipid peroxidation of cell membranes
- protect membrane from breaking down by phospholipid A - neutralizes oxidis LDL (makes it less injurious), i.e. cardioprotective |
|
|
Who gets Vitamine E deficiency?
|
Cystic Fibrosis Patients
|
|
|
Does vitamin E deficiency cause hemolytic anemia?
|
Yes! Susceptible to membrane damage (radical)
|
|
|
Does vitamin E help myelin?
|
Yes! Problems neurologicly since they disrupt the membranes in the brain. Spinalcerebellar Dz
|
|
|
What vitamin enhances the activity of warfarin?
|
Vitamin E excess!
|
|
|
What changes k2(inactive) to k1?
|
epoxide reductase
k1 gamma carboxylates activates factors II, VII, IX, X hydroxylates proline and lisine activates them so they are fucntional |
|
|
Warfarin does what?
|
Blocks epoxide reductase, all vitamin K is K2 (inactive)
|
|
|
Vitamine K deficiency?
|
Prolong Antibiotics
Poor Diets New Borns |
