Usmle Step 1: Diseases And Contraindicated Medications

Front 1

What medication do you avoid in Alzheimer's Disease or Myasthenia Gravis?

Back 1

Tricyclic Antidepressants.
(anti-Ach properties, especially tertiary TCA's)

Front 2

What medication do you avoid in Prinzmetal's angina or CAD?
(3)

Back 2

Sumatriptan (Side effect - coronary vasospasm)
Hydralazine (creates compensatory tachycardia after smooth muscle)
Minoxidil (same reason as Hydralazine)

Front 3

What medication do you avoid in Gout?
(think kidney)

Back 3

Hydrochlorothiazide and loop Diuretics

Front 4

What medication do you avoid in Asthmatics or patients with severe allergies?
(cardiac medication)

Back 4

Beta Blockers. Can prevent life-saving effects of beta-agonist or epinephrine, respectively

Front 5

What medication do you avoid in diabetics?
(cardiac medication)

Back 5

Beta Blockers if at all possible. Can mask the symptoms of hypoglycemia.

Front 6

What medication do you avoid in patients with gallstones?
(cholesterol lowering agent)

Back 6

Bile acid resins (e.g. cholestyramine, colestipol, colesevelem)
Can also inhibit uptake of certain medications, notably digoxin

Front 7

What medication do you avoid in renal failure?
(cardiac medication)(antibiotic)

Back 7

DIGOXIN!! Renally excreted
and
Floroquinolones. Renally excreted

Front 8

What medication do you avoid in patients with recent heart attack?
(antiarrhythmic)

Back 8

NO NOT GIVE Class IC.
antiarrhythmics
Pro-arrhythmic. Contraindicated post-MI

Front 9

What medication do you avoid in patients with propensity toward acute angle glaucoma?

Back 9

ATROPINE
(in acute attack, do not give epinephrine either. Can increase pressure)