Usmle Step 1

Front 1

Acetaminophen antidote

Back 1

N-acetylcysteine

Front 2

Prostaglandin actions

Back 2

increase uterine tone
decrease vascular tone
decrease broncial tone

Front 3

Acetaminophen antidote

Back 3

N-acetylcysteine

Front 4

gamma interferon therapy

Back 4

chronic granulomatous disease

Front 5

Beta interferon therapy

Back 5

multiple sclerosis

Front 6

alpha interferon therapy

Back 6

Hepatitis B and C
Kaposi's sarcoma
leukemiaa
malignant melanoma

Front 7

function of myelin

Back 7

increase space constant (allows signal to travel a greater distance)

Front 8

origin of CNS/PNS supportive cells

Back 8

microglia--mesoderm
astrocytes, ependymal, oligodendrogila, schwann--ectoderm

Front 9

Meissner's corpuscles

Back 9

small encapulated
light discriminatory touch
hairless skin

Front 10

Radial nerve injury

Back 10

shaft of humerous
wrist drop

Front 11

median nerve injury

Back 11

supracondyle of humerous
loss of forearm pronation, wrist and finger flexion, leads to thenar atrophy

Front 12

ulnar nerve injury

Back 12

medial epicondyle
claw hand

Front 13

axillary nerve injury

Back 13

surgical neck of humerous or ant should dislocation
loss of deltoid action

Front 14

Atropine-like side effects

Back 14

Trycyclics

Front 15

cardiac toxicity

Back 15

doxorubicin (Adriamycin), daunorubicin

Front 16

coronary vasospasm

Back 16

cocaines

Front 17

cutaneous flushing

Back 17

Niacin, Calcium channel blockers, adenosine, vancomycin

Front 18

Torsades des pointes

Back 18

class III (sotolol), class IA (quinidine), antiarrhythmics, cisapride

Front 19

agranulocytosis

Back 19

clozapine, carbamazepine, colchicine

Front 20

aplastic anemia

Back 20

chloramphenicol, benzene, NSAIDs

Front 21

hemolysis in G6PD deficient patients

Back 21

sulfonamides, INH, aspirin, ibuprofen, primaquine, nitrofurantion

Front 22

thrombotic complications

Back 22

OCP

Front 23

drug reaction: cough

Back 23

ACE inhibitors (avoid with losartan)

Front 24

pulmonary fibrosis

Back 24

bleomycin, amidarone, busulfan

Front 25

acute cholestatic hepatitis

Back 25

macrolides

Front 26

massive to focal hepatic necrosis

Back 26

halothane, valproic acid, acetominophen, amanita phalloides

Front 27

drug reaction: hepatitis

Back 27

INH

Front 28

Pseudomembranous colitis

Back 28

clindamycin, ampicillin

Front 29

adrenocortical insufficiency

Back 29

glucocorticoid withdrawal (HPA) suppression

Front 30

gynecomastia

Back 30

Spironolactone, digitalis, cimetidine, chronic EtOH use, estrogens, Ketonazole

Front 31

hot flashes

Back 31

tamoxifen

Front 32

gingival hyperplasia

Back 32

phenytoin

Front 33

photosensitivity

Back 33

sulfonamides, amiodarone, tetracycline

Front 34

SLE-like syndrome

Back 34

hydralazine, INH, procainamide, phenytoin

Front 35

tendonitis, tendon rupture and cartialige damage (kids)

Back 35

fluoroquinolones

Front 36

fanconi's syndrome

Back 36

expired tetracycline

Front 37

intersitial nephritis

Back 37

methicillin

Front 38

hemorragic cystitis

Back 38

cyclophosphamide, ifosfamid

Front 39

cinchonism

Back 39

quinidine, quinine

Front 40

diabetes insipidus

Back 40

lithium, demeclocycline

Front 41

Seizures

Back 41

buproprion, imipenem/cilastatin

Front 42

disulfram-like reaction

Back 42

metronidazole, certain cephalosporins, procarbazine, sulfonylureas

Front 43

nephrotoxicity, ototoxicity

Back 43

aminoglycosides, loop diuretics, cisplatin

Front 44

P450 inducers

Back 44

Quinidine
barbituates
phenytoin
rifampin
griseofulvin
carbamazepine
st john's wart

Front 45

P450 inhibitors

Back 45

INH
sulfonamides
cimetidine
ketonazole
erythromycin
grapefruit juice

Front 46

beta blocker overdose antidote

Back 46

glucagon

Front 47

digitalis overdose treatment

Back 47

stop digitalis
normalized potassium
lidocain
anti-digitalis Fab fragments
Magnesium

Front 48

cyanide overdose antidote

Back 48

nitrite, hydroxocobalamin, thiosulfate

Front 49

methemoglobin antidote

Back 49

methylene blue

Front 50

mehtanol, ethylene glycol antidote

Back 50

ethanol

Front 51

benzodiazepine antidote

Back 51

flumazenil

Front 52

TCA overdose antidote

Back 52

NaHCO3

Front 53

streptokinase, tPA antidote

Back 53

aminocaproic acid

Front 54

mets to brain

Back 54

Lung, breast, skin, kidney, GI

Front 55

mets to liver

Back 55

colon, stomach, pancreas, breast, lung

Front 56

mets to bone

Back 56

prostate, thyroid, testes, breast, lung, kidney

Front 57

colorectal cancer tumor suppressor gene

Back 57

APC
chromosome 5q

Front 58

colon cancer tumor suppressor gene

Back 58

DCC
chromosome 18q