Usmle Microbiology Qbook 3

Front 1

2 most common causes of meningitis in neonates up to 1 month

Back 1

S. agalactiae

E. coli

Front 2

DOC for Otitis Media in children

Back 2

Amoxicillin

Front 3

Polyribitol phosphate capsule

Back 3

H. influenza type b

*not present in other H. flu types that cause Otitis media

Front 4

Characteristic more frequently associated with Klebsiella pneumo than with P. aeruginosa

Back 4

Upper lobe cavitation

Front 5

What do both N. gonorrhoeae and Chlamydia trachomatis induce?

Back 5

Endocytosis by epithelial cells

Front 6

Encapsulated, gram - rod that grows on Bordet-gengou media

10 day history of paroxysms of coughing

Back 6

Bordetella pertussis

Front 7

"General paralysis fo the insane"
-inappropriate sexual advances
-deficits in memory
-expressionless facies, tremor

Back 7

Treponema pallidum = Tertiarty Syphillis

Front 8

Frothy, yellow vaginal discharge

DOC: Metronidazole

Back 8

Trichomonas vaginalis

Front 9

Iodine-staining intraepithelial inclusion bodies on a smear from an odorless cervical discharge that contains sloughed epithelial cells and scant neutrophils

Back 9

Chlamydia trachomatis

Front 10

4 Obligate Aerobes

Back 10

Nagging Pests Must Breathe

1. Nocardia
2. P. aeruginosa
3. M. TB
4. Bacillus

Front 11

Most common cause of Anaerobic infection including abdominal abscesses and peritonitis

Back 11

Bacteroides fragilis

Front 12

Drugs ineffective againsts Anaerobes

Back 12

Amin-O2-glycosides

Front 13

DOC for Traveler's diarrhea that contains fecal leukocytes

Back 13

Floxacins
-cipro
-norfloxacin

Front 14

DOC's for Malaria

Back 14

Quinine

Front 15

Drug that causes yellow teeth in neonates and its mode of action

Back 15

Tetracycline

inhibits aminoacyl-tRNA binding (binds 30S subunit)

Front 16

Antibacterial that inhibits Peptidyl transferase of 50S subunit

Aplastic anemia

Back 16

Chloramphenicol

Front 17

7 year old girl develops behavioral changes and her performance in school begins to deteriorate.
Several months later she develops a seizure disorder, ataxia, and focal neurologic symptoms
She is eventually quadriparetic, spastic, and unresponsive
She dies within 1 year

Back 17

Measles = Subacute Sclerosing Panencephalitis

Front 18

Fever, myalgia, cough -> 4 days -> ARDS

Deer mouse droppings

Back 18

Hantavirus (Bunyaviridae)

Front 19

Type of Ab's that are cold agglutinins seen in Mycoplasma infections

Back 19

IgM

Front 20

DOC for pneumonia when patient is allergic to penicillin

Back 20

Erythromycin (macrolide) = inhibits 50S translocase

Front 21

Rickettsia species transmitted by the feces of the rat flea

Outward spreading rash

Back 21

R. typhi = Endemic typhus

Front 22

Rickettsia species prominent during times of war and social upheaval and spread by the feces of the body louse, Pediculus humanis

Back 22

Epidemic typhus = R. prowazekii

Front 23

Rickettsia species resistant to dehydration and can be acquired by inhaling dust contaminated by animals

Back 23

Coxiella burnetii = Q fever

Front 24

Alternate complement pathway (C5-C8) is important for clearing this genus

Back 24

Neisseria

Front 25

What immune response is protective against S. pneumo?

Back 25

IgG Ab's to surface acidic polysaccharide

Front 26

Loose stools, fever, headache in a boy who owns turtles

Back 26

Salmonella

Front 27

Waxy envelope

Back 27

Mycobacteria

Front 28

Sensitive to bacitracin

Back 28

Pyogenes

Front 29

Sensitive to Optochin

Back 29

S. pneumo

"Pnew option"

Front 30

Bacterial cause of RUQ pain, vomiting, jaundice, and itching

Similar to Ascaris Lumbricoides = biliary tract obstruction

Back 30

Clonorchis sinesis = suppurative cholangitis

Front 31

How do people get Lyme Disease?

Back 31

Ixodes ticks

Front 32

Erythema chronicum migrans

Myopericarditis

Chronic Polyarthritis

Back 32

Lyme Disease = Borrelia burgdorferi

Front 33

Brill-Zinsser disease

Back 33

Reactivation of R. prowazekii that was not treated with antibiotics

Front 34

2 weeks after birth, a neonate develops sepsis, skin vesicles, and conjunctivitis. Over the next several days, the baby's condition deteriorates with development of seizures, CN palsies, and lethargy. The baby dies approximately 1 week after onset of symptoms

Back 34

Herpes Simplex II
-causes the devastating neonatal encephalitis acquired during birth

Front 35

Neutrophils in the CSF in a 1 week old baby with nuchal rigidity

Back 35

E. coli

S. agalactia

Front 36

Sickle cell anemia + Osteomyelitis

Motile and does not ferment lactose

Gram - rod

Back 36

Salmonella

Front 37

Virus whose disease or sequelae are more severe if infection occurs at a very young age

Back 37

HBV -> Hepatocellular Carcinoma

Front 38

Causative agent of Tinea Versicolor = hypopigmented skin lesions which typically occur hot, humid weather

Back 38

Malassezia furfur

Front 39

River Blindness transmitted by Black flies

Back 39

Onchocerca

Front 40

Microbe causing Relapsing Fever which is transmitted by ticks or louse

Visualized with Aniline dyes (Giemsa or Wright's stain)

Back 40

Borrelia recurrentis

Front 41

Name 4 natural transformers = uptake and integration of naked DNA by a bacteria from the environment

Back 41

H-HeNS

1. H. influenza
2. Helicobacter pylori
3. Neisseria gonorrhoeae
4. Streptococci

Front 42

A 23-year old woman comes into emergency room with a fever. She notes the recent development of nausea, diarrhea, and a rash. Her last menstrual period began 3 days ago. Physical exam reveals blood pressure 90/45 and HR of 120. A diffuse erythematous rash with areas of desquamation over the hands and feet is noted.

Back 42

S. aureus TSST-1

Front 43

What protects Gram +'s from the lytic action of detergents?

Back 43

Thick Peptidoglycan layer

Front 44

Forms abscesses
Gram + cocci
B-hemolysis
Mannitol salt fermentation

Back 44

S. aureus

Front 45

What mechanism mediates Strep pneumo's attachment to respiratory mucosa?

Back 45

production of IgA protease

Front 46

What stage are spores formed?

Back 46

Stationary phase

Front 47

DOC for Cryptococcal meningitis

Back 47

Amphotericin B + Flucytosine

Front 48

What is Isoniazid used for?

Back 48

M. tuberculosis

Front 49

Alpha-hemolytic streptococcus

Back 49

Strep pneumo + viridans

Front 50

How is Doxycycline different from other Tetracyclines?

Back 50

It is excreted in the feces instead of urine

Patients with RENAL dysfunction should be given Doxycycline

Front 51

Hemolytic anemia + Hepatosplenomegaly

transmitted by Ixodes ticks

Back 51

Babesia

Front 52

Influenza-like illness that resolves in a few days
Less than week later: muscle pain, spasms, sensory disturbances
2 days later: flaccid paralysis

Back 52

Poliomyelitis

Front 53

Chronic meningitis: Lymphocytes, plasma cells, macrophages, fibroblasts

agent?

Back 53

Mycobacterium tuberculosis

Front 54

General cause of Acute Lymphocytic Meningitis (no neutrophils present)

Back 54

Viruses

Front 55

Pneumonia with green sputum

Back 55

P. aeruginosa

Front 56

Most common cause of Bronchiolitis and Pneumonia in infants < 1 year old

Back 56

RSV

Front 57

Causes Colorado tick fever, the only tick-borne VIRAL disease in the U.S.

Back 57

Orbivirus

Front 58

Most common cause of Otitis Externa

Back 58

P. aeruginosa

Front 59

"Barking" cough

Back 59

Parainfluenza virus = Croup

Front 60

Food poisoning with an 18-24 hr incubation that is associated with home-canned vegetable and sausages

Back 60

Clostridium perfringens and botulinum = spores

Front 61

Causes glanders in humans with close contact with horses

Back 61

Pseudomonas mallei

Front 62

Rat-bite fever agent

Back 62

Streptobacillus moniliformis

Front 63

Demyelination of white matter only with abnormal giant oligodendrocytes with eosinophilic inclusions

Back 63

JC virus in an AIDS patient = Progressive Multifocal Leukoencephalopathy

Front 64

Soil organism
Cavitary pulmonary disease in IC'ed
Partially acid-fast (mycolic acid in cell wall)

Back 64

Nocardia asteroides

Front 65

How does Chlamydia trachomatis cause blindness?

Back 65

Scarring of the cornea

Front 66

Anti-treponemal antibody test whose titer rises early and stays elevated throughout the lifetime of the host or until treatment is completed

Back 66

FTA-ABS

Front 67

Nontreponemal test that detects antibodies that cross-react with mammalian cardiolipid called reaginic antibodies
-titers fall in late stage syphillis

Back 67

VDRL

Front 68

Curved
Motile = flagella
Oxidase +
Gram - rods
Blood and pus in diarrhea
Lower abdominal pain

Back 68

Campylobacter jejuni

Front 69

Microaerophilic growth at 42' C

Back 69

Campylobacter jejuni

Front 70

Drugs that inhibits Dihydrofolate Reductase

Back 70

Trimethoprim

Front 71

Drug that inhibits Folate synthesis (Dihydropteroate synthase)

Back 71

Sulfonamide

Front 72

Drug that inhibits RNA polymerase

Back 72

Rifampin

Front 73

Drugs that inhibit the attachment of aminoacyl-tRNA to ribosome

Back 73

Tetracycline
-doxycline

Front 74

Drugs that inhibit the formation of the initiation complex of 30S ribosomal subunit

Back 74

Aminoglycosides
-Gentamicin
-Tobramycin
-Streptomycin

Front 75

Drugs that inhibit DNA gyrase

Back 75

Quinolones
-Ciprofloxacin

Front 76

"smoky" colored urine
Hypertension
Mild generalized edema
RBC casts

Back 76

PostSTREPTOCOCCAL glomerulonephritis

Front 77

General pathogen that can replicate in enucleated cells?

Back 77

most RNA viruses b/c they replicate in the cytoplasm