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77 Cards in this Set

  • Front
  • Back
2 most common causes of meningitis in neonates up to 1 month
S. agalactiae

E. coli
DOC for Otitis Media in children
Polyribitol phosphate capsule
H. influenza type b

*not present in other H. flu types that cause Otitis media
Characteristic more frequently associated with Klebsiella pneumo than with P. aeruginosa
Upper lobe cavitation
What do both N. gonorrhoeae and Chlamydia trachomatis induce?
Endocytosis by epithelial cells
Encapsulated, gram - rod that grows on Bordet-gengou media

10 day history of paroxysms of coughing
Bordetella pertussis
"General paralysis fo the insane"
-inappropriate sexual advances
-deficits in memory
-expressionless facies, tremor
Treponema pallidum = Tertiarty Syphillis
Frothy, yellow vaginal discharge

DOC: Metronidazole
Trichomonas vaginalis
Iodine-staining intraepithelial inclusion bodies on a smear from an odorless cervical discharge that contains sloughed epithelial cells and scant neutrophils
Chlamydia trachomatis
4 Obligate Aerobes
Nagging Pests Must Breathe

1. Nocardia
2. P. aeruginosa
3. M. TB
4. Bacillus
Most common cause of Anaerobic infection including abdominal abscesses and peritonitis
Bacteroides fragilis
Drugs ineffective againsts Anaerobes
DOC for Traveler's diarrhea that contains fecal leukocytes
DOC's for Malaria
Drug that causes yellow teeth in neonates and its mode of action

inhibits aminoacyl-tRNA binding (binds 30S subunit)
Antibacterial that inhibits Peptidyl transferase of 50S subunit

Aplastic anemia
7 year old girl develops behavioral changes and her performance in school begins to deteriorate.
Several months later she develops a seizure disorder, ataxia, and focal neurologic symptoms
She is eventually quadriparetic, spastic, and unresponsive
She dies within 1 year
Measles = Subacute Sclerosing Panencephalitis
Fever, myalgia, cough -> 4 days -> ARDS

Deer mouse droppings
Hantavirus (Bunyaviridae)
Type of Ab's that are cold agglutinins seen in Mycoplasma infections
DOC for pneumonia when patient is allergic to penicillin
Erythromycin (macrolide) = inhibits 50S translocase
Rickettsia species transmitted by the feces of the rat flea

Outward spreading rash
R. typhi = Endemic typhus
Rickettsia species prominent during times of war and social upheaval and spread by the feces of the body louse, Pediculus humanis
Epidemic typhus = R. prowazekii
Rickettsia species resistant to dehydration and can be acquired by inhaling dust contaminated by animals
Coxiella burnetii = Q fever
Alternate complement pathway (C5-C8) is important for clearing this genus
What immune response is protective against S. pneumo?
IgG Ab's to surface acidic polysaccharide
Loose stools, fever, headache in a boy who owns turtles
Waxy envelope
Sensitive to bacitracin
Sensitive to Optochin
S. pneumo

"Pnew option"
Bacterial cause of RUQ pain, vomiting, jaundice, and itching

Similar to Ascaris Lumbricoides = biliary tract obstruction
Clonorchis sinesis = suppurative cholangitis
How do people get Lyme Disease?
Ixodes ticks
Erythema chronicum migrans


Chronic Polyarthritis
Lyme Disease = Borrelia burgdorferi
Brill-Zinsser disease
Reactivation of R. prowazekii that was not treated with antibiotics
2 weeks after birth, a neonate develops sepsis, skin vesicles, and conjunctivitis. Over the next several days, the baby's condition deteriorates with development of seizures, CN palsies, and lethargy. The baby dies approximately 1 week after onset of symptoms
Herpes Simplex II
-causes the devastating neonatal encephalitis acquired during birth
Neutrophils in the CSF in a 1 week old baby with nuchal rigidity
E. coli

S. agalactia
Sickle cell anemia + Osteomyelitis

Motile and does not ferment lactose

Gram - rod
Virus whose disease or sequelae are more severe if infection occurs at a very young age
HBV -> Hepatocellular Carcinoma
Causative agent of Tinea Versicolor = hypopigmented skin lesions which typically occur hot, humid weather
Malassezia furfur
River Blindness transmitted by Black flies
Microbe causing Relapsing Fever which is transmitted by ticks or louse

Visualized with Aniline dyes (Giemsa or Wright's stain)
Borrelia recurrentis
Name 4 natural transformers = uptake and integration of naked DNA by a bacteria from the environment

1. H. influenza
2. Helicobacter pylori
3. Neisseria gonorrhoeae
4. Streptococci
A 23-year old woman comes into emergency room with a fever. She notes the recent development of nausea, diarrhea, and a rash. Her last menstrual period began 3 days ago. Physical exam reveals blood pressure 90/45 and HR of 120. A diffuse erythematous rash with areas of desquamation over the hands and feet is noted.
S. aureus TSST-1
What protects Gram +'s from the lytic action of detergents?
Thick Peptidoglycan layer
Forms abscesses
Gram + cocci
Mannitol salt fermentation
S. aureus
What mechanism mediates Strep pneumo's attachment to respiratory mucosa?
production of IgA protease
What stage are spores formed?
Stationary phase
DOC for Cryptococcal meningitis
Amphotericin B + Flucytosine
What is Isoniazid used for?
M. tuberculosis
Alpha-hemolytic streptococcus
Strep pneumo + viridans
How is Doxycycline different from other Tetracyclines?
It is excreted in the feces instead of urine

Patients with RENAL dysfunction should be given Doxycycline
Hemolytic anemia + Hepatosplenomegaly

transmitted by Ixodes ticks
Influenza-like illness that resolves in a few days
Less than week later: muscle pain, spasms, sensory disturbances
2 days later: flaccid paralysis
Chronic meningitis: Lymphocytes, plasma cells, macrophages, fibroblasts

Mycobacterium tuberculosis
General cause of Acute Lymphocytic Meningitis (no neutrophils present)
Pneumonia with green sputum
P. aeruginosa
Most common cause of Bronchiolitis and Pneumonia in infants < 1 year old
Causes Colorado tick fever, the only tick-borne VIRAL disease in the U.S.
Most common cause of Otitis Externa
P. aeruginosa
"Barking" cough
Parainfluenza virus = Croup
Food poisoning with an 18-24 hr incubation that is associated with home-canned vegetable and sausages
Clostridium perfringens and botulinum = spores
Causes glanders in humans with close contact with horses
Pseudomonas mallei
Rat-bite fever agent
Streptobacillus moniliformis
Demyelination of white matter only with abnormal giant oligodendrocytes with eosinophilic inclusions
JC virus in an AIDS patient = Progressive Multifocal Leukoencephalopathy
Soil organism
Cavitary pulmonary disease in IC'ed
Partially acid-fast (mycolic acid in cell wall)
Nocardia asteroides
How does Chlamydia trachomatis cause blindness?
Scarring of the cornea
Anti-treponemal antibody test whose titer rises early and stays elevated throughout the lifetime of the host or until treatment is completed
Nontreponemal test that detects antibodies that cross-react with mammalian cardiolipid called reaginic antibodies
-titers fall in late stage syphillis
Motile = flagella
Oxidase +
Gram - rods
Blood and pus in diarrhea
Lower abdominal pain
Campylobacter jejuni
Microaerophilic growth at 42' C
Campylobacter jejuni
Drugs that inhibits Dihydrofolate Reductase
Drug that inhibits Folate synthesis (Dihydropteroate synthase)
Drug that inhibits RNA polymerase
Drugs that inhibit the attachment of aminoacyl-tRNA to ribosome
Drugs that inhibit the formation of the initiation complex of 30S ribosomal subunit
Drugs that inhibit DNA gyrase
"smoky" colored urine
Mild generalized edema
RBC casts
PostSTREPTOCOCCAL glomerulonephritis
General pathogen that can replicate in enucleated cells?
most RNA viruses b/c they replicate in the cytoplasm