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8 Cards in this Set

  • Front
  • Back
What is the direct effect of digoxin
Inbhibition of cardiac Na, K ATPase
What is the Indirect effect of Digoxin
inhibition of Neuronal Na, K ATPase
When would you use Digoxin
CHF
Supraventricular Tachycardias (except wolff-parkinson-white syndrome)
What are the early signs of side effects of digoxin
Anorexia, nausea, ECG changes
What are the later signs of side effects of Digoxin
Disorientation, Visual effects (halos)
What are the Toxic Side effects of Digoxin
Any cardiac arrhythmias = life threatening
How do you manage the toxicity of Digoxin
Use of Fab antibodies towards digoxin
supportive therapy (electrolyes and antiarrhythmics class 1b)
What are the Drug interactions of Digoxin
Diuretics - decrease K, Mg, and increase Ca
Quinidine and verapamil = displace digoxin = toxicity